- Senior physician
- Medical Specialist in Internal Medicine and Hematology and Oncology
- Palliative Medicine
Areas of expertise
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Hematology
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Oncology
Memberships
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DKG, AIO, ESMO
Publications
Synthesis and new DNA targeting activity of 6- and 7-tert-butylfascaplysins
Dyshlovoy S, Mansour W, Ramm N, Hauschild J, Zhidkov M, Kriegs M, Zielinski A, Hoffer K, Busenbender T, Glumakova K, Spirin P, Prassolov V, Tilki D, Graefen M, Bokemeyer C, von Amsberg G
SCI REP-UK. 2024;14(1):11788.
Applications of Nanopore sequencing in precision cancer medicine
Dyshlovoy S, Paigin S, Afflerbach A, Lobermeyer A, Werner S, Schüller U, Bokemeyer C, Schuh A, Bergmann L, von Amsberg G, Joosse S
INT J CANCER. 2024;155(12):2129-2140.
Master corepressor inactivation through multivalent SLiM-induced polymerization mediated by the oncogene suppressor RAI2
Goradia N, Werner S, Mullapudi E, Greimeier S, Bergmann L, Lang A, Mertens H, Węglarz A, Sander S, Chojnowski G, Wikman H, Ohlenschläger O, von Amsberg G, Pantel K, Wilmanns M
NAT COMMUN. 2024;15(1):5241.
Das fortgeschrittene Nierenzellkarzinom – Aktuelle Systemtherapie im Überblick
Kaune M, Bokemeyer C, von Amsberg G
DEUT MED WOCHENSCHR. 2024;149(4):180-190.
Androgendeprivationstherapie und kardiovaskuläre Morbidität beim Prostatakarzinom: ein narratives Review
Klemm J, von Deimling M, Fisch M, Kramer G, Tilki D, Steuber T, von Amsberg G, Hengstenberg C, Shariat S
UROLOGE. 2024;63(3):262-268.
Lectins CGL and MTL, representatives of mytilectin family, exhibit different antiproliferative activity in Burkitt's lymphoma cells
Kuzmich A, Filshtein A, Likhatskaya G, Gorpenchenko T, Chikalovets I, Mizgina T, Hua K, von Amsberg G, Dyshlovoy S, Chernikov O
IUBMB LIFE. 2024;76(12):1279-1294.
A Combined Cyto- and Histopathological Diagnostic Approach Reduces Time to Diagnosis and Time to Therapy in First Manifestation of Metastatic Spinal Disease: A Cohort Study
Leonhardt L, Heuer A, Stangenberg M, Schroeder M, Schmidt G, Welker L, von Amsberg G, Strahl A, Krüger L, Dreimann M, Bokemeyer C, Viezens L, Asemissen A
CANCERS. 2024;16(9):.
Limited prognostic role of routine serum markers (AP, CEA, LDH and NSE) in oligorecurrent prostate cancer patients undergoing PSMA-radioguided surgery
Mehring G, Steinbach C, Pose R, Knipper S, Koehler D, Werner S, Riethdorf S, von Amsberg G, Ambrosini F, Maurer T
WORLD J UROL. 2024;42(1):256.
Stonikacidin A, an Antimicrobial 4-Bromopyrrole Alkaloid Containing L-Idonic Acid Core from the Northwestern Pacific Marine Sponge Lissodendoryx papillosa
Tabakmakher K, Makarieva T, Sabutski Y, Kokoulin M, Menshov A, Popov R, Guzii A, Shubina L, Chingizova E, Chingizov A, Yurchenko E, Fedorov S, Grebnev B, von Amsberg G, Dyshlovoy S, Ivanchina N, Dmitrenok P
MAR DRUGS. 2024;22(9):.
PSMA PET-directed surgical metastasis-directed therapy in metachronous prostate cancer
Ambrosini F, Koehler D, Ghadban T, Jacobsen F, Knipper S, von Amsberg G, Steuber T, Maurer T
CENT EUR J UROL. 2023;76(3):182-185.
Rhizochalinin Exhibits Anticancer Activity and Synergizes with EGFR Inhibitors in Glioblastoma In Vitro Models
Dyshlovoy S, Hauschild J, Venz S, Krisp C, Kolbe K, Zapf S, Heinemann S, Fita K, Shubina L, Makarieva T, Guzii A, Rohlfing T, Kaune M, Busenbender T, Mair T, Moritz M, Poverennaya E, Schlüter H, Serdyuk V, Stonik V, Dierlamm J, Bokemeyer C, Mohme M, Westphal M, Lamszus K, von Amsberg G, Maire C
MOL PHARMACEUT. 2023;20(10):4994-5005.
New Marine Fungal Deoxy-14,15-Dehydroisoaustamide Resensitizes Prostate Cancer Cells to Enzalutamide
Dyshlovoy S, Zhuravleva O, Hauschild J, Busenbender T, Pelageev D, Yurchenko A, Khudyakova Y, Antonov A, Graefen M, Bokemeyer C, von Amsberg G
MAR DRUGS. 2023;21(1):.
Preclinical patient-derived modeling of castration-resistant prostate cancer facilitates individualized assessment of homologous recombination repair deficient disease
Elsesy M, Oh-Hohenhorst S, Oing C, Eckhardt A, Burdak-Rothkamm S, Alawi M, Müller C, Schüller U, Maurer T, von Amsberg G, Petersen C, Rothkamm K, Mansour W
MOL ONCOL. 2023;17(6):1129-1147.
New Bioactive β-Resorcylic Acid Derivatives from the Alga-Derived Fungus Penicillium antarcticum KMM 4685
Leshchenko E, Antonov A, Borkunov G, Hauschild J, Zhuravleva O, Khudyakova Y, Menshov A, Popov R, Kim N, Graefen M, Bokemeyer C, von Amsberg G, Yurchenko A, Dyshlovoy S
MAR DRUGS. 2023;21(3):.
Anticancer Activity of the Marine Triterpene Glycoside Cucumarioside A2-2 in Human Prostate Cancer Cells
Menchinskaya E, Dyshlovoy S, Venz S, Jacobsen C, Hauschild J, Rohlfing T, Silchenko A, Avilov S, Balabanov S, Bokemeyer C, Aminin D, von Amsberg G, Honecker F
MAR DRUGS. 2023;22(1):.
Experimental in vitro, ex vivo and in vivo models in prostate cancer research
Sailer V, von Amsberg G, Duensing S, Kirfel J, Lieb V, Metzger E, Offermann A, Pantel K, Schuele R, Taubert H, Wach S, Perner S, Werner S, Aigner A
NAT REV UROL. 2023;20(3):158-178.
A New Mild Method for Synthesis of Marine Alkaloid Fascaplysin and Its Therapeutically Promising Derivatives
Tryapkin O, Kantemirov A, Dyshlovoy S, Prassolov V, Spirin P, von Amsberg G, Sidorova M, Zhidkov M
MAR DRUGS. 2023;21(8):.
Salvage Chemotherapy with Cisplatin, Ifosfamide, and Paclitaxel in Aggressive Variant of Metastatic Castration-Resistant Prostate Cancer
Amsberg G, Zilles M, Mansour W, Gild P, Alsdorf W, Kaune M, Böckelmann L, Hauschild J, Krisp C, Rohlfing T, Saygi C, Alawi M, Zielinski A, Langebrake C, Su X, Perner S, Tilki D, Schluter H, Graefen M, Dyshlovoy S, Bokemeyer C
INT J MOL SCI. 2022;23(23):.
Cytoreductive radical prostatectomy after chemohormonal therapy in patients with primary metastatic prostate cancer
Babst C, Amiel T, Maurer T, Knipper S, Lunger L, Tauber R, Retz M, Herkommer K, Eiber M, von Amsberg G, Graefen M, Gschwend J, Steuber T, Heck M
ASIAN J UROL. 2022;9(1):69-74.
Expression Patterns and Corepressor Function of Retinoic Acid-induced 2 in Prostate Cancer
Besler K, Węglarz A, Keller L, von Amsberg G, Bednarz-Knoll N, Offermann A, Stoupiec S, Eltze E, Semjonow A, Boettcher L, Schneegans S, Perner S, Hauch S, Todenhöfer T, Peine S, Pantel K, Wikman H, Werner S
CLIN CHEM. 2022;68(7):973-983.
Cytotoxic N-Methylpretrichodermamide B Reveals Anticancer Activity and Inhibits P-Glycoprotein in Drug-Resistant Prostate Cancer Cells
Dyshlovoy S, Busenbender T, Hauschild J, Girich E, Kriegs M, Hoffer K, Graefen M, Yurchenko A, Bokemeyer C, Amsberg G
MAR DRUGS. 2022;20(10):.
1-O-Alkylglycerol Ethers from the Marine Sponge Guitarra abbotti and Their Cytotoxic Activity
Dyshlovoy S, Fedorov S, Svetashev V, Makarieva T, Kalinovsky A, Moiseenko O, Krasokhin V, Shubina L, Guzii A, von Amsberg G, Stonik V
MAR DRUGS. 2022;20(7):.
New Guanidine Alkaloids Batzelladines O and P from the Marine Sponge Monanchora pulchra Induce Apoptosis and Autophagy in Prostate Cancer Cells
Dyshlovoy S, Shubina L, Makarieva T, Guzii A, Hauschild J, Strewinsky N, Berdyshev D, Kudryashova E, Menshov A, Popov R, Dmitrenok P, Graefen M, Bokemeyer C, Amsberg G
MAR DRUGS. 2022;20(12):.
New diterpenes from the marine sponge Spongionella sp. overcome drug resistance in prostate cancer by inhibition of P-glycoprotein
Dyshlovoy S, Shubina L, Makarieva T, Hauschild J, Strewinsky N, Guzii A, Menshov A, Popov R, Grebnev B, Busenbender T, Oh-Hohenhorst S, Maurer T, Tilki D, Graefen M, Bokemeyer C, Stonik V, von Amsberg G
SCI REP-UK. 2022;12(1):.
Meroantarctines A-C, Meroterpenoids with Rearranged Skeletons from the Alga-Derived Fungus Penicillium antarcticum KMM 4685 with Potent p-Glycoprotein Inhibitory Activity
Leshchenko E, Antonov A, Dyshlovoy S, Berdyshev D, Hauschild J, Zhuravleva O, Menshov A, Kirichuk N, Popov R, Gerasimenko A, Udovenko A, Graefen M, Bokemeyer C, von Amsberg G, Yurchenko A
J NAT PROD. 2022;85(12):2746-2752.
Aggressive variants of prostate cancer: underlying mechanisms of neuroendocrine transdifferentiation
Merkens L, Sailer V, Lessel D, Janzen E, Greimeier S, Kirfel J, Perner S, Pantel K, Werner S, von Amsberg G
J EXP CLIN CANC RES. 2022;41(1):.
Immunotherapy in Advanced Prostate Cancer-Light at the End of the Tunnel?
von Amsberg G, Alsdorf W, Karagiannis P, Coym A, Kaune M, Werner S, Graefen M, Bokemeyer C, Merkens L, Dyshlovoy S
INT J MOL SCI. 2022;23(5):.
Neue Follow-up-Daten zu Studien in der Uroonkologie
von Amsberg G, Bokemeyer C
Im Fokus Onkologie. 2022;25(4):40-41.
Study of Structure-Activity Relationships of the Marine Alkaloid Fascaplysin and Its Derivatives as Potent Anticancer Agents
Zhidkov M, Kaune M, Kantemirov A, Smirnova P, Spirin P, Sidorova M, Stadnik S, Shyrokova E, Kaluzhny D, Tryapkin O, Busenbender T, Hauschild J, Rohlfing T, Prassolov V, Bokemeyer C, Graefen M, von Amsberg G, Dyshlovoy S
MAR DRUGS. 2022;20(3):.
New Antibacterial Chloro-Containing Polyketides from the Alga-Derived Fungus Asteromyces cruciatus KMM 4696
Zhuravleva O, Oleinikova G, Antonov A, Kirichuk N, Pelageev D, Rasin A, Menshov A, Popov R, Kim N, Chingizova E, Chingizov A, Volchkova O, von Amsberg G, Dyshlovoy S, Yurchenko E, Guzhova I, Yurchenko A
J FUNGI. 2022;8(5):.
AXL Inhibition Represents a Novel Therapeutic Approach in BCR-ABL Negative Myeloproliferative Neoplasms
Beitzen-Heineke A, Berenbrok N, Waizenegger J, Päsler S, Gensch V, Udonta F, Vargas-Delgado M, Engelmann J, Hoffmann F, Schafhausen P, von Amsberg G, Riecken K, Beumer N, Imbusch C, Lorens J, Fischer T, Pantel K, Bokemeyer C, Ben Batalla I, Loges S
HEMASPHERE. 2021;5(9):.
Activity of New Synthetic (2-Chloroethylthio)-1,4-naphthoquinones in Prostate Cancer Cells
Dyshlovoy S, Pelageev D, Jakob L, Borisova K, Hauschild J, Busenbender T, Kaune M, Khmelevskaya E, Graefen M, Bokemeyer C, Anufriev V, von Amsberg G
PHARMACEUTICALS-BASE. 2021;14(10):949.
Multimodal therapy in oligometastatic prostate cancer: A glimpse into the future?
Knipper S, von Amsberg G, Stolzenbach F, Steuber T, Heck M, Eiber M, Berliner C, Maurer T
ASIAN J UROL. 2021;8(2):248-250.
Polyketides metabolites from the marine sediment-derived fungus Thermomyces lanuginosus Tsikl. KMM 4681
Sobolevskaya M, Berdyshev D, Zhuravleva O, Denisenko V, Dyshlovoy S, von Amsberg G, Khudyakova Y, Kirichuk N, Afiyatullov S
PHYTOCHEM LETT. 2021;41:114-118.
Cytotoxic Marine Alkaloid 3,10-Dibromofascaplysin Induces Apoptosis and Synergizes with Cytarabine Resulting in Leukemia Cell Death
Spirin P, Shyrokova E, Lebedev T, Vagapova E, Smirnova P, Kantemirov A, Dyshlovoy S, Amsberg G, Zhidkov M, Prassolov V
MAR DRUGS. 2021;19(9):.
A real-world comparison of docetaxel versus abiraterone acetate for metastatic hormone-sensitive prostate cancer
Tsaur I, Heidegger I, Bektic J, Kafka M, van den Bergh R, Hunting J, Thomas A, Brandt M, Höfner T, Debedde E, Thibault C, Ermacora P, Zattoni F, Foti S, Kretschmer A, Ploussard G, Rodler S, von Amsberg G, Tilki D, Surcel C, Rosenzweig B, Gadot M, Gandaglia G, Dotzauer R
CANCER MED-US. 2021;10(18):6354-6364.
Systemtherapie bei metastasierten Keimzelltumoren des Hodens
von Amsberg G, Bokemeyer C
2021. Medikamente in der Urologie. Merseberger A, Kramer M (eds.). 1. ed. Springer, 475-494.
Diagnose und Therapie seltener Hodentumoren am Beispiel des malignen Mesothelioms der Tunica vaginalis testis und Sertoli-Zell-Tumoren
von Amsberg G, Sehovic M, Hartmann M, Bokemeyer C
UROLOGE. 2021;60(7):872-879.
Kardiovaskuläre Komplikationen unter Androgenentzugstherapie: Vorteil für Gonadotropin-Releasing-Hormon-Antagonisten? Ein Update
von Amsberg G, Thiele H, Merseburger A
UROLOGE. 2021;60(11):1450-1457.
New Deoxyisoaustamide Derivatives from the Coral-Derived Fungus Penicillium dimorphosporum KMM 4689
Zhuravleva O, Antonov A, Trang V, Pivkin M, Khudyakova Y, Denisenko V, Popov R, Kim N, Yurchenko E, Gerasimenko A, Udovenko A, Amsberg G, Dyshlovoy S, Afiyatullov S
MAR DRUGS. 2021;19(1):.
Evaluation of PD-L1 expression on circulating tumor cells (CTCs) in patients with advanced urothelial carcinoma (UC)
Bergmann S, Coym A, Ott L, Soave A, Rink M, Janning M, Stoupiec M, Coith C, Peine S, von Amsberg G, Pantel K, Riethdorf S
ONCOIMMUNOLOGY. 2020;9(1):.
Efficacy and Mechanism of Action of Marine Alkaloid 3,10-Dibromofascaplysin in Drug-Resistant Prostate Cancer Cells
Dyshlovoy S, Kaune M, Hauschild J, Kriegs M, Hoffer K, Busenbender T, Smirnova P, Zhidkov M, Poverennaya E, Oh-Hohenhorst S, Spirin P, Prassolov V, Tilki D, Bokemeyer C, Graefen M, von Amsberg G
MAR DRUGS. 2020;18(12):.
Marine alkaloid monanchoxymycalin C: a new specific activator of JNK1/2 kinase with anticancer properties
Dyshlovoy S, Kaune M, Kriegs M, Hauschild J, Busenbender T, Shubina L, Makarieva T, Hoffer K, Bokemeyer C, Graefen M, Stonik V, von Amsberg G
SCI REP-UK. 2020;10(1):13178.
Urupocidin C: a new marine guanidine alkaloid which selectively kills prostate cancer cells via mitochondria targeting
Dyshlovoy S, Kudryashova E, Kaune M, Makarieva T, Shubina L, Busenbender T, Denisenko V, Popov R, Hauschild J, Fedorov S, Bokemeyer C, Graefen M, Stonik V, von Amsberg G
SCI REP-UK. 2020;10(1):9764.
Inspired by Sea Urchins: Warburg Effect Mediated Selectivity of Novel Synthetic Non-Glycoside 1,4-Naphthoquinone-6S-Glucose Conjugates in Prostate Cancer
Dyshlovoy S, Pelageev D, Hauschild J, Sabutskii Y, Khmelevskaya E, Krisp C, Kaune M, Venz S, Borisova K, Busenbender T, Denisenko V, Schlüter H, Bokemeyer C, Graefen M, Polonik S, Anufriev V, Amsberg G
MAR DRUGS. 2020;18(5):.
Polyphenolic Compounds from Lespedeza Bicolor Root Bark Inhibit Progression of Human Prostate Cancer Cells via Induction of Apoptosis and Cell Cycle Arrest
Dyshlovoy S, Tarbeeva D, Fedoreyev S, Busenbender T, Kaune M, Veselova M, Kalinovskiy A, Hauschild J, Grigorchuk V, Kim N, Bokemeyer C, Graefen M, Gorovoy P, von Amsberg G
BIOMOLECULES. 2020;10(3):.
Leptogorgins A-C, Humulane Sesquiterpenoids from the Vietnamese Gorgonian Leptogorgia sp
Kapustina I, Makarieva T, Guzii A, Kalinovsky A, Popov R, Dyshlovoy S, Grebnev B, Amsberg G, Stonik V
MAR DRUGS. 2020;18(6):.
Sea Anemone Heteractis crispa Actinoporin Demonstrates In Vitro Anticancer Activities and Prevents HT-29 Colorectal Cancer Cell Migration
Kvetkina A, Malyarenko O, Pavlenko A, Dyshlovoy S, von Amsberg G, Ermakova S, Leychenko E
MOLECULES. 2020;25(24):.
CARD-Studie – Bedeutung für die Therapie des fortgeschrittenen Prostatakarzinoms
Merseburger A, Bannowsky A, Becker K, Bokemeyer C, Eichenauer R, Lehmann J, Mickisch G, Steuber T, von Amsberg G, von Kügelgen T, Wülfing C
AKTUEL UROL. 2020;2020:.
Gracilosulfates A-G, Monosulfated Polyoxygenated Steroids from the Marine Sponge Haliclona gracilis
Shubina L, Makarieva T, Denisenko V, Popov R, Dyshlovoy S, Grebnev B, Dmitrenok P, von Amsberg G, Stonik V
MAR DRUGS. 2020;18(9):.
Extreme biomineralization: the case of the hypermineralized ear bone of gray whale (Eschrichtius robustus)
Wysokowski M, Petrenko I, Galli R, Schimpf C, Rafaja D, Hubalkova J, Aneziris C, Dyshlovoy S, von Amsberg G, Meissner H, Yakovlev Y, Tabachnick K, Stelling A, Ehrlich H
APPL PHYS A-MATER. 2020;126(9):.
Citriperazines A-D produced by a marine algae-derived fungus Penicillium sp. KMM 4672
Yurchenko A, Berdyshev D, Smetanina O, Ivanets E, Zhuravleva O, Rasin A, Khudyakova Y, Popov R, Dyshlovoy S, von Amsberg G, Afiyatullov S
NAT PROD RES. 2020;34(8):1118-1123.
Piltunines A-F from the Marine-Derived Fungus Penicillium piltunense KMM 4668
Afiyatullov S, Zhuravleva O, Antonov A, Leshchenko E, Pivkin M, Khudyakova Y, Denisenko V, Pislyagin E, Kim N, Berdyshev D, Amsberg G, Dyshlovoy S
MAR DRUGS. 2019;17(11):.
Naphto-Γ-pyrones from the marine-derived fungus Aspergillus foetidus
Antonov A, Leshchenko E, Zhuravleva O, Dyshlovoy S, von Amsberg G, Popov R, Denisenko V, Kirichuk N, Afiyatullov S
NAT PROD RES. 2019;1-4.
Successful Targeting of the Warburg Effect in Prostate Cancer by Glucose-Conjugated 1,4-Naphthoquinones
Dyshlovoy S, Pelageev D, Hauschild J, Borisova K, Kaune M, Krisp C, Venz S, Sabutskii Y, Khmelevskaya E, Busenbender T, Denisenko V, Pokhilo N, Atopkina L, Graefen M, Schlüter H, Stonik V, Bokemeyer C, Anufriev V, von Amsberg G
CANCERS. 2019;11(11):.
Detection of Androgen Receptor Variant 7 (ARV7) mRNA Levels in EpCAM-Enriched CTC Fractions for Monitoring Response to Androgen Targeting Therapies in Prostate Cancer
Hille C, Gorges T, Riethdorf S, Mazel M, Steuber T, Amsberg G, König F, Peine S, Alix-Panabières C, Pantel K
CELLS-BASEL. 2019;8(9):.
Response to olaparib in a PALB2 germline mutated prostate cancer and genetic events associated with resistance
Horak P, Weischenfeldt J, von Amsberg G, Beyer B, Schütte A, Uhrig S, Gieldon L, Klink B, Feuerbach L, Hübschmann D, Kreutzfeldt S, Heining C, Maier S, Hutter B, Penzel R, Schlesner M, Eils R, Sauter G, Stenzinger A, Brors B, Schröck E, Glimm H, Fröhling S, Schlomm T
CSH MOL CASE STUD. 2019;5(2):.
Biologically Active Echinulin-Related Indolediketopiperazines from the Marine Sediment-Derived Fungus Aspergillus niveoglaucus
Smetanina O, Yurchenko A, Girich Ivanets E, Trinh P, Antonov A, Dyshlovoy S, von Amsberg G, Kim N, Chingizova E, Pislyagin E, Menchinskaya E, Yurchenko E, Van T, Afiyatullov S
MOLECULES. 2019;25(1):.
New Trisulfated Steroids from the Vietnamese Marine Sponge Halichondria vansoesti and Their PSA Expression and Glucose Uptake Inhibitory Activities
Tabakmakher K, Makarieva T, Denisenko V, Popov R, Dmitrenok P, Dyshlovoy S, Grebnev B, Bokemeyer C, von Amsberg G, Cuong N
MAR DRUGS. 2019;17(8):.
Auroglaucin-related neuroprotective compounds from Vietnamese marine sediment-derived fungus Aspergillus niveoglaucus
Yurchenko A, Smetanina O, Ivanets E, Phan T, Ngo N, Zhuravleva O, Rasin A, Dyshlovoy S, Menchinskaya E, Pislyagin E, von Amsberg G, Afiyatullov S, Yurchenko E
NAT PROD RES. 2019 [Epub ahead of print];1-6.
Biologically Active Metabolites from the Marine Sediment-Derived Fungus Aspergillus flocculosus
Yurchenko A, Trinh P, Girich Ivanets E, Smetanina O, Rasin A, Popov R, Dyshlovoy S, von Amsberg G, Menchinskaya E, Thanh Van T, Afiyatullov S
MAR DRUGS. 2019;17(10):.
Total Syntheses and Preliminary Biological Evaluation of Brominated Fascaplysin and Reticulatine Alkaloids and Their Analogues
Zhidkov M, Smirnova P, Tryapkin O, Kantemirov A, Khudyakova Y, Malyarenko O, Ermakova S, Grigorchuk V, Kaune M, Amsberg G, Dyshlovoy S
MAR DRUGS. 2019;17(9):.
Prenylated indole alkaloids from co-culture of marine-derived fungi Aspergillus sulphureus and Isaria felina
Afiyatullov S, Zhuravleva O, Antonov A, Berdyshev D, Pivkin M, Denisenko V, Popov R, Gerasimenko A, von Amsberg G, Dyshlovoy S, Leshchenko E, Yurchenko A
J ANTIBIOT. 2018;71(10):846-853.
Synthesis and anticancer activity of the derivatives of marine compound rhizochalin in castration resistant prostate cancer
Dyshlovoy S, Otte K, Tabakmakher K, Hauschild J, Makarieva T, Shubina L, Fedorov S, Bokemeyer C, Stonik V, von Amsberg G
ONCOTARGET. 2018;9(24):16962-16973.
In Situ Detection and Quantification of AR-V7, AR-FL, PSA, and KRAS Point Mutations in Circulating Tumor Cells
El-Heliebi A, Hille C, Laxman N, Svedlund J, Haudum C, Ercan E, Kroneis T, Chen S, Smolle M, Rossmann C, Krzywkowski T, Ahlford A, Darai E, von Amsberg G, Alsdorf W, König F, Löhr M, de Kruijff I, Riethdorf S, Gorges T, Pantel K, Bauernhofer T, Nilsson M, Sedlmayr P
CLIN CHEM. 2018;64(3):536-546.
Cost-effectiveness analyses and cost analyses in castration-resistant prostate cancer: A systematic review
Grochtdreis T, König H, Dobruschkin A, von Amsberg G, Dams J
PLOS ONE. 2018;13(12):e0208063.
Asperindoles A⁻D and a -Terphenyl Derivative from the Ascidian-Derived Fungus sp. KMM 4676
Ivanets E, Yurchenko A, Smetanina O, Rasin A, Zhuravleva O, Pivkin M, Popov R, von Amsberg G, Afiyatullov S, Dyshlovoy S
MAR DRUGS. 2018;16(7):232.
Treatment of Metastatic Spindle Epithelial Tumor with Thymus-Like Differentiation (SETTLE) - Long-Term Disease Control by Multimodal Therapy
Quidde J, Alsdorf W, von Amsberg G, Wilczak W, Bokemeyer C
ONCOL RES TREAT. 2018;41(1-2):58-60.
Zosteropenillines: Polyketides from the Marine-Derived Fungus Penicillium thomii
Afiyatullov S, Leshchenko E, Berdyshev D, Sobolevskaya M, Antonov A, Denisenko V, Popov R, Pivkin M, Udovenko A, Pislyagin E, von Amsberg G, Dyshlovoy S, Kerr R
MAR DRUGS. 2017;15(2):46.
Axl Blockade by BGB324 Inhibits BCR-ABL Tyrosine Kinase Inhibitor-Sensitive and -Resistant Chronic Myeloid Leukemia
Ben Batalla I, Erdmann R, Jørgensen H, Mitchell R, Ernst T, von Amsberg G, Schafhausen P, Velthaus J, Rankin S, Clark R, Koschmieder S, Schultze A, Mitra S, Vandenberghe P, Brümmendorf T, Carmeliet P, Hochhaus A, Pantel K, Bokemeyer C, Helgason G, Holyoake T, Loges S
CLIN CANCER RES. 2017;23(9):2289-2300.
The marine triterpene glycoside frondoside A induces p53-independent apoptosis and inhibits autophagy in urothelial carcinoma cells
Dyshlovoy S, Madanchi R, Hauschild J, Otte K, Alsdorf W, Schumacher U, Kalinin V, Silchenko A, Avilov S, Honecker F, Stonik V, Bokemeyer C, von Amsberg G
BMC CANCER. 2017;17(1):93.
Proteomic-based investigations on the mode of action of the marine anticancer compound rhizochalinin
Dyshlovoy S, Otte K, Venz S, Hauschild J, Junker H, Makarieva T, Balabanov S, Alsdorf W, Madanchi R, Honecker F, Bokemeyer C, Stonik V, von Amsberg G
PROTEOMICS. 2017;17(11):.
Frondoside A induces AIF-associated caspase-independent apoptosis in Burkitt lymphoma cells
Dyshlovoy S, Rast S, Hauschild J, Otte K, Alsdorf W, Madanchi R, Kalinin V, Silchenko A, Avilov S, Dierlamm J, Honecker F, Stonik V, Bokemeyer C, von Amsberg G
LEUKEMIA LYMPHOMA. 2017;58(12):2905-2915.
The Inhibitory Activity of Luzonicosides from the Starfish Echinaster luzonicus against Human Melanoma Cells
Malyarenko O, Dyshlovoy S, Kicha A, Ivanchina N, Malyarenko T, Carsten B, Gunhild v, Stonik V, Ermakova S
MAR DRUGS. 2017;15(7):.
Platinum-refractory germ cell tumors: an update on current treatment options and developments
Oing C, Alsdorf W, von Amsberg G, Oechsle K, Bokemeyer C
WORLD J UROL. 2017;35(8):1167-1175.
Monoubiquitination of histone H2B – a potential new target in treatment resistant germ cell tumors.
Oing C, Dyshlovoy S, Burandt E, Amsberg G, Honecker F, Bokemeyer C, Rothkamm K, Mansour W
ONCOL RES TREAT. 2017;40:95-96.
Systemische Behandlung des Harnblasenkarzinoms: Klassische Chemotherapie und neue Optionen
Oing C, von Amsberg G, Bokemeyer C
Im Fokus Onkologie. 2017;20(9):50-56.
Monanchoxymycalin C with anticancer properties, new analogue of crambescidin 800 from the marine sponge Monanchora pulchra
Shubina L, Makarieva T, von Amsberg G, Denisenko V, Popov R, Dyshlovoy S
NAT PROD RES. 2017;1-8.
Unique prostate cancer-toxic polyketides from marine sediment-derived fungus Isaria felina
Smetanina O, Yurchenko A, Ivanets E, Kalinovsky A, Khudyakova Y, Dyshlovoy S, von Amsberg G, Yurchenko E, Afiyatullov S
J ANTIBIOT. 2017;70(7):856-858.
A nonrandomized, prospective, clinical study on the impact of circulating tumor cells on outcomes of urothelial carcinoma of the bladder patients treated with radical cystectomy with or without adjuvant chemotherapy
Soave A, Riethdorf S, Dahlem R, von Amsberg G, Minner S, Weisbach L, Engel O, Fisch M, Pantel K, Rink M
INT J CANCER. 2017;140(2):381-389.
Neue Aspekte in der Therapie des metastasierten Prostatakarzinoms
von Amsberg G, Bokemeyer C
DEUT MED WOCHENSCHR. 2017;142(15):1106-1110.
Metabolites of the Marine Fungus Aspergillus candidus KMM 4676 Associated with a Kuril Colonial Ascidian
Yurchenko A, Ivanets E, Smetanina O, Pivkin M, Dyshlovoi S, von Amsberg G, Afiyatullov S
CHEM NAT COMPD+. 2017;53(4):747-749.
The marine triterpene glycoside frondoside A exhibits activity in vitro and in vivo in prostate cancer
Dyshlovoy S, Menchinskaya E, Venz S, Rast S, Amann K, Hauschild J, Otte K, Kalinin V, Silchenko A, Avilov S, Alsdorf W, Madanchi R, Bokemeyer C, Schumacher U, Walther R, Aminin D, Fedorov S, Shubina L, Stonik V, Balabanov S, Honecker F, von Amsberg G
INT J CANCER. 2016;138(10):2450-65.
Marine compound rhizochalinin shows high in vitro and in vivo efficacy in castration resistant prostate cancer
Dyshlovoy S, Otte K, Alsdorf W, Hauschild J, Lange T, Venz S, Bauer C, Bähring R, Amann K, Mandanchi R, Schumacher U, Schröder-Schwarz J, Makarieva T, Guzii A, Tabakmakher K, Fedorov S, Shubina L, Kasheverov I, Ehmke H, Steuber T, Stonik V, Bokemeyer C, Honecker F, von Amsberg G
ONCOTARGET. 2016;7(43):69703 - 69717.
Guanidine Alkaloids from the Marine Sponge Monanchora pulchra Show Cytotoxic Properties and Prevent EGF-Induced Neoplastic Transformation in Vitro
Dyshlovoy S, Tabakmakher K, Hauschild J, Shchekaleva R, Otte K, Guzii A, Makarieva T, Kudryashova E, Fedorov S, Shubina L, Bokemeyer C, Honecker F, Stonik V, von Amsberg G
MAR DRUGS. 2016;14(7):E133.
Anti-migratory activity of marine alkaloid monanchocidin A - proteomics-based discovery and confirmation
Dyshlovoy S, Venz S, Hauschild J, Tabakmakher K, Otte K, Madanchi R, Walther R, Guzii A, Makarieva T, Shubina L, Fedorov S, Stonik V, Bokemeyer C, Balabanov S, Honecker F, von Amsberg G
PROTEOMICS. 2016;16(10):1590-603.
Cabazitaxel overcomes cisplatin resistance in germ cell tumour cells
Gerwing M, Jacobsen C, Dyshlovoy S, Hauschild J, Rohlfing T, Oing C, Venz S, Oldenburg J, Oechsle K, Bokemeyer C, von Amsberg G, Honecker F
J CANCER RES CLIN. 2016;142(9):1979-94.
Melonoside A: An ω-Glycosylated Fatty Acid Amide from the Far Eastern Marine Sponge Melonanchora kobjakovae
Guzii A, Makarieva T, Denisenko V, Dmitrenok P, Kuzmich A, Dyshlovoy S, von Amsberg G, Krasokhin V, Stonik V
ORG LETT. 2016;18(14):3478-81.
Second Line Chemotherapy for Advanced and Metastatic Urothelial Carcinoma: Vinflunine and Beyond-A Comprehensive Review of the Current Literature
Oing C, Rink M, Oechsle K, Seidel C, von Amsberg G, Bokemeyer C
J UROLOGY. 2016;195(2):254-63.
Pharmacotherapeutic treatment of germ cell tumors - standard of care and recent developments
Oing C, Seidel C, von Amsberg G, Oechsle K, Bokemeyer C
EXPERT OPIN PHARMACO. 2016;17(4):545-60.
Absolute Configuration and Body Part Distribution of the Alkaloid 6-epi-Monanchorin from the Marine Polychaete Chaetopterus variopedatus
Shubina L, Makarieva T, Denisenko V, Dmitrenok P, Dyshlovoy S, von Amsberg G, Glazunov V, Silchenko A, Stonik V
NAT PROD COMMUN. 2016;11(9):1253-1257.
Pallidopenillines: Polyketides from the Alga-Derived Fungus Penicillium thomii Maire KMM 4675
Sobolevskaya M, Leshchenko E, Hoai T, Denisenko V, Dyshlovoy S, Kirichuk N, Khudyakova Y, Kim N, Berdyshev D, Pislyagin E, Kuzmich A, Gerasimenko A, Popov R, von Amsberg G, Antonov A, Afiyatullov S
J NAT PROD. 2016;79(12):3031-3038.
Activity of nintedanib in germ cell tumors
Steinemann G, Jacobsen C, Gerwing M, Hauschild J, Amsberg G, Höpfner M, Nitzsche B, Honecker F
ANTI-CANCER DRUG. 2016;27(2):89-98.
Fortschritte in der Therapie urogenitaler Tumoren
von Amsberg G, Bokemeyer C
Im Fokus Onkologie. 2016;19(7-8):64.
Pretrichodermamides D-F from a Marine Algicolous Fungus Penicillium sp. KMM 4672
Yurchenko A, Smetanina O, Ivanets E, Kalinovsky A, Khudyakova Y, Kirichuk N, Popov R, Bokemeyer C, von Amsberg G, Chingizova E, Afiyatullov S, Dyshlovoy S
MAR DRUGS. 2016;14(7):E122.
Marine alkaloid Monanchocidin a overcomes drug resistance by induction of autophagy and lysosomal membrane permeabilization
Dyshlovoy S, Hauschild J, Amann K, Tabakmakher K, Venz S, Walther R, Guzii A, Makarieva T, Shubina L, Fedorov S, Stonik V, Bokemeyer C, Balabanov S, Honecker F, Amsberg G
ONCOTARGET. 2015;6(19):17328-41.
Systemic treatment of vulvar cancer
Mahner S, Prieske K, Grimm D, Trillsch F, Prieske S, von Amsberg G, Petersen C, Müller V, Jänicke F, Woelber L
EXPERT REV ANTICANC. 2015;15(6):629-37.
Beyond Bevacizumab: An Outlook to New Anti-Angiogenics for the Treatment of Ovarian Cancer
Mahner S, Woelber L, Müller V, Witzel I, Prieske K, Grimm D, von Amsberg G, Trillsch F
FRONT ONCOL. 2015;5:211.
Management of advanced bladder cancer in the era of targeted therapies
Soave A, Engel O, von Amsberg G, Becker A, Dahlem R, Shariat S, Fisch M, Rink M
MINERVA UROL NEFROL. 2015;67(2):103-15.
Viele innovative Substanzen: Kastrationsresistentes fortgeschrittenes Prostatakarzinom
von Amsberg G, Steuber T, Bokemeyer C
Deutsches Ärzteblatt. 2015;112(20):8-10.
Bosutinib
Amsberg G, Brümmendorf T
2014. Molekular zielgerichtete Therapie der chronischen myeloischen Leukämie (CML). Brümmendorf T, Koschmieder S (eds.). 1. ed. Bremen-London-Boston: Uni-Med, 71-75.
Aktuelle Therapiekonzepte bei kastrationsresistenten Prostatakarzinom
Amsberg G, Strölin P, Bokemeyer C, Steuber T
DEUT MED WOCHENSCHR. 2014;139(41):2086-90.
Aaptamines from the marine sponge Aaptos sp. display anticancer activities in human cancer cell lines and modulate AP-1-, NF-κB-, and p53-dependent transcriptional activity in mouse JB6 Cl41 cells
Dyshlovoy S, Fedorov S, Shubina L, Kuzmich A, Bokemeyer C, Amsberg G, Honecker F
BIOMED RES INT . 2014;2014:469309.
Clinical management of epithelial ovarian cancer during pregnancy
Grimm D, Woelber L, Trillsch F, Keller-v. Amsberg G, Mahner S
EUR J CANCER. 2014;50(5):963-971.
Bosutinib: a novel second-generation tyrosine kinase inhibitor
Isfort S, Amsberg G, Schafhausen P, Koschmieder S, Brümmendorf T
Recent Results Cancer Res. 2014;201:81-97.
Quinone-carbohydrate nonglucoside conjugates as a new type of cytotoxic agents: synthesis and determination of in vitro activity
Pelageev D, Dyshlovoy S, Pokhilo N, Denisenko V, Borisova K, Amsberg G, Bokemeyer C, Fedorov S, Honecker F, Anufriev V
EUR J MED CHEM. 2014;77:139-44.
Moderne Systemtherapie des fortgeschrittenen Prostatakarzinoms
Steuber T, Stroeilin P, Amsberg G
Onkologie heute. 2014;(04):22-25.
Bosutinib in the management of chronic myelogenous leukemia
Amsberg G, Schafhausen P
BIOL-TARGETS THER. 2013;7:115-22.
Combination of a proteomics approach and reengineering of meso scale network models for prediction of mode-of-action for tyrosine kinase inhibitors
Balabanov S, Wilhelm T, Venz S, Amsberg G, Scharf C, Pospisil H, Balabanov M, Barett C, Bokemeyer C, Walther R, Brümmendorf T, Schuppert A
PLOS ONE. 2013;8(1):e53668.
Targeting aurora kinases with danusertib (PHA-739358) inhibits growth of liver metastases from gastroenteropancreatic neuroendocrine tumors in an orthotopic xenograft model.
Fraedrich K, Schrader J, Ittrich H, von Amsberg G, Gontarewicz A, Matzat V, Kromminga A, Pace A, Moll J, Bläker M, Lohse A, Hörsch D, Brümmendorf T, Benten D
CLIN CANCER RES. 2012;18(17):4621-4632.
Novel aspects of therapy with the dual Src and Abl kinase inhibitor bosutinib in chronic myeloid leukemia.
von Amsberg G, Brümmendorf T
EXPERT REV ANTICANC. 2012;12(9):1121-1127.
Abcg2 overexpression represents a novel mechanism for acquired resistance to the multi-kinase inhibitor Danusertib in BCR-ABL-positive cells in vitro.
Balabanov S, Gontarewicz A, von Amsberg G, Raddrizzani L, Balabanov M, Bosotti R, Moll J, Jost E, Barett C, Rohe I, Bokemeyer C, Holyoake T, Brümmendorf T
PLOS ONE. 2011;6(4):19164.
Multi tyrosine kinase inhibitor dasatinib as novel cause of severe pre-capillary pulmonary hypertension?
Hennigs J, von Amsberg G, Baumann H, Honecker F, Kluge S, Bokemeyer C, Brümmendorf T, Klose H
BMC PULM MED. 2011;11:30.
Bosutinib.
von Amsberg G, Schafhausen P, Brümmendorf T
Recent Results Cancer Res. 2010;184:119-127.
Simultaneous targeting of Aurora kinases and Bcr-Abl kinase by the small molecule inhibitor PHA-739358 is effective against imatinib-resistant BCR-ABL mutations including T315I.
Gontarewicz A, Balabanov S, von Amsberg G, Colombo R, Graziano A, Pesenti E, Benten D, Bokemeyer C, Fiedler W, Moll J, Brümmendorf T
BLOOD. 2008;111(8):4355-4364.
PHA-680626 exhibits anti-proliferative and pro-apoptotic activity on Imatinib-resistant chronic myeloid leukemia cell lines and primary CD34+ cells by inhibition of both Bcr-Abl tyrosine kinase and Aurora kinases.
Gontarewicz A, Balabanov S, von Amsberg G, Panse J, Schafhausen P, Bokemeyer C, Fiedler W, Moll J, Brümmendorf T
LEUKEMIA RES. 2008;32(12):1857-1865.
Esophageal squamous cell carcinoma presenting with extensive skin lesions: a case report
Iwanski G, Block A, von Amsberg G, Münch J, Claus S, Fiedler W, Bokemeyer C
J MED CASE REP. 2008;2:115.
Letzte Aktualisierung aus dem FIS: 24.12.2024 - 03:57 Uhr