Unclassifiable CNS tumors in DNA methylation-based classification: clinical challenges and prognostic impact
Drexler R, Brembach F, Sauvigny J, Ricklefs F, Eckhardt A, Bode H, Gempt J, Lamszus K, Westphal M, Schüller U, Mohme M
ACTA NEUROPATHOL COM. 2024;12(1):9.

A prognostic neural epigenetic signature in high-grade glioma
Drexler R, Khatri R, Sauvigny T, Mohme M, Maire C, Ryba A, Zghaibeh Y, Dührsen L, Salviano-Silva A, Lamszus K, Westphal M, Gempt J, Wefers A, Neumann J, Bode H, Hausmann F, Huber T, Bonn S, Jütten K, Delev D, Weber K, Harter P, Onken J, Vajkoczy P, Capper D, Wiestler B, Weller M, Snijder B, Buck A, Weiss T, Göller P, Sahm F, Menstel J, Zimmer D, Keough M, Ni L, Monje M, Silverbush D, Hovestadt V, Suvà M, Krishna S, Hervey-Jumper S, Schüller U, Heiland D, Hänzelmann S, Ricklefs F
NAT MED. 2024;30(6):1622-1635.

Temporal change of DNA methylation subclasses between matched newly diagnosed and recurrent glioblastoma
Drexler R, Khatri R, Schüller U, Eckhardt A, Ryba A, Sauvigny T, Dührsen L, Mohme M, Ricklefs T, Bode H, Hausmann F, Huber T, Bonn S, Voß H, Neumann J, Silverbush D, Hovestadt V, Suvà M, Lamszus K, Gempt J, Westphal M, Heiland D, Hänzelmann S, Ricklefs F
ACTA NEUROPATHOL. 2024;147(1):21.

Premotor cortical beta synchronization and the network neuromodulation of externally paced finger tapping in Parkinson's disease
Gulberti A, Schneider T, Galindo-Leon E, Heise M, Pino A, Westphal M, Hamel W, Buhmann C, Zittel S, Gerloff C, Pötter-Nerger M, Engel A, Moll C
NEUROBIOL DIS. 2024;197:.

SARS-CoV-2-associated T-cell infiltration in the central nervous system
Mohme M, Schultheiß C, Piffko A, Fitzek A, Paschold L, Thiele B, Püschel K, Glatzel M, Westphal M, Lamszus K, Matschke J, Binder M
CLIN TRANSL IMMUNOL. 2024;13(2):e1487.

Circulating Tumor Cells and Thromboembolic Events in Patients with Glioblastoma
Rolling C, Mohme M, Bokemeyer C, Westphal M, Riethdorf S, Lamszus K, Pantel K, Klingler F, Langer F
HAMOSTASEOLOGIE. 2024 [Epub ahead of print].

Microsurgical Clipping of Unruptured Anterior Circulation Aneurysms-A Global Multicenter Investigation of Perioperative Outcomes
Sauvigny J, Drexler R, Pantel T, Ricklefs F, Catapano J, Wanebo J, Lawton M, Sanchin A, Hecht N, Vajkoczy P, Raygor K, Tonetti D, Abla A, El Naamani K, Tjoumakaris S, Jabbour P, Jankowitz B, Salem M, Burkhardt J, Wagner A, Wostrack M, Gempt J, Meyer B, Gaub M, Mascitelli J, Dodier P, Bavinzski G, Roessler K, Stroh N, Gmeiner M, Gruber A, Figueiredo E, Coelho A, Bervitskiy A, Anisimov E, Rzaev J, Krenzlin H, Keric N, Ringel F, Park D, Kim M, Marcati E, Cenzato M, Krause L, Westphal M, Dührsen L, Sauvigny T
NEUROSURGERY. 2024 [Epub ahead of print];94(6):1218-26.

External validation of the Chicago Chiari Outcome Scale in adults with Chiari malformation type I
Antkowiak L, Stogowski P, Klepinowski T, Balinski T, Mado H, Sumislawski P, Niedbala M, Rucinska M, Nowaczyk Z, Rogalska M, Kocur D, Kasperczuk A, Sordyl R, Kloc W, Kaspera W, Kammler G, Sagan L, Rudnik A, Tabakow P, Westphal M, Mandera M
NEUROSURG FOCUS. 2023;54(3):E3.

Local delivery of hrBMP4 as an anticancer therapy in patients with recurrent glioblastoma: a first-in-human phase 1 dose escalation trial
Bos E, Binda E, Verploegh I, Wembacher E, Hoefnagel D, Balvers R, Korporaal A, Conidi A, Warnert E, Trivieri N, Visioli A, Zaccarini P, Caiola L, van Wijck R, van der Spek P, Huylebroeck D, Leenstra S, Lamfers M, Ram Z, Westphal M, Noske D, Legnani F, DiMeco F, Vescovi A, Dirven C
MOL CANCER. 2023;22(1):129.

Multiple craniotomies in a single surgery - the resection of scattered brain metastases
Bschorer M, Ricklefs F, Sauvigny T, Westphal M, Dührsen L
NEUROSURG REV. 2023;46(1):70.

Acute low-pressure hydrocephalus in aneurysmal subarachnoid hemorrhage
Czorlich P, Schweingruber N, Göttsche J, Mader M, Westphal M
NEUROSURG FOCUS. 2023;54(4):E5.

Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerability
Drexler R, Khatri R, Sauvigny T, Mohme M, Maire C, Ryba A, Zghaibeh Y, Dührsen L, Salviano-Silva A, Lamszus K, Westphal M, Gempt J, Wefers A, Neumann J, Bode H, Hausmann F, Huber T, Bonn S, Jütten K, Delev D, Weber K, Harter P, Onken J, Vajkoczy P, Capper D, Wiestler B, Weller M, Snijder B, Buck A, Weiss T, Keough M, Ni L, Monje M, Silverbush D, Hovestadt V, Suvà M, Krishna S, Hervey-Jumper S, Schüller U, Heiland D, Hänzelmann S, Ricklefs F
bioRxiv. 2023.

Association of the classification of intraoperative adverse events (ClassIntra) with complications and neurological outcome after neurosurgical procedures: a prospective cohort study
Drexler R, Ricklefs F, Pantel T, Göttsche J, Nitzschke R, Zöllner C, Westphal M, Dührsen L
ACTA NEUROCHIR. 2023;165(8):2015-2027.

Defining benchmark outcomes for transsphenoidal surgery of pituitary adenomas: a multicenter analysis
Drexler R, Rotermund R, Smith T, Kilgallon J, Honegger J, Nasi-Kordhishti I, Gardner P, Gersey Z, Abdallah H, Jane J, Marino A, Knappe U, Uksul N, Rzaev J, Galushko E, Gormolysova E, Bervitskiy A, Schroeder H, Eördögh M, Losa M, Mortini P, Gerlach R, Azab M, Budohoski K, Rennert R, Karsy M, Couldwell W, Antunes A, Westphal M, Ricklefs F, Flitsch J
EUR J ENDOCRINOL. 2023;189(3):379-386.

Epigenetic profiling reveals a strong association between lack of 5-ALA fluorescence and EGFR amplification in IDH-wildtype glioblastoma
Drexler R, Sauvigny T, Schüller U, Eckhardt A, Maire C, Khatri R, Hausmann F, Hänzelmann S, Huber T, Bonn S, Bode H, Lamszus K, Westphal M, Dührsen L, Ricklefs F
NEURO-ONCOL PRACT. 2023;10(5):462-471.

DNA methylation subclasses predict the benefit from gross total tumor resection in IDH-wildtype glioblastoma patients
Drexler R, Schüller U, Eckhardt A, Filipski K, Hartung T, Harter P, Divé I, Forster M, Czabanka M, Jelgersma C, Onken J, Vajkoczy P, Capper D, Siewert C, Sauvigny T, Lamszus K, Westphal M, Dührsen L, Ricklefs F
NEURO-ONCOLOGY. 2023;25(2):315-325.

Rhizochalinin Exhibits Anticancer Activity and Synergizes with EGFR Inhibitors in Glioblastoma In Vitro Models
Dyshlovoy S, Hauschild J, Venz S, Krisp C, Kolbe K, Zapf S, Heinemann S, Fita K, Shubina L, Makarieva T, Guzii A, Rohlfing T, Kaune M, Busenbender T, Mair T, Moritz M, Poverennaya E, Schlüter H, Serdyuk V, Stonik V, Dierlamm J, Bokemeyer C, Mohme M, Westphal M, Lamszus K, von Amsberg G, Maire C
MOL PHARMACEUT. 2023;20(10):4994-5005.

Terson Syndrome in Patients with Aneurysmal Subarachnoid Hemorrhage - A 10-Year Single-Center Experience
Göttsche J, Knospe V, Sauvigny T, Schweingruber N, Grensemann J, Spitzer M, Westphal M, Skevas C, Czorlich P
NEUROCRIT CARE. 2023;39(1):155-161.

Subthalamic and nigral neurons are differentially modulated during parkinsonian gait
Gulberti A, Wagner J, Horn M, Reuss J, Heise M, Koeppen J, Pinnschmidt H, Westphal M, Engel A, Gerloff C, Sharott A, Hamel W, Moll C, Pötter-Nerger M
BRAIN. 2023;146(7):2766-2779.

Cerebrospinal fluid penetration of fosfomycin in patients with ventriculitis: an observational study
König C, Martens-Lobenhoffer J, Czorlich P, Westphal M, Bode-Böger S, Kluge S, Grensemann J
ANN CLIN MICROB ANTI. 2023;22(1):29.

Extracorporeal membrane oxygenation in traumatic brain injury - A retrospective, multicenter cohort study
Mader M, Lefering R, Westphal M, Maegele M, Czorlich P
INJURY. 2023;54(5):1271-1277.

A 64-year progression of an intradiploic epidermoid of the frontal skull: illustrative case
Ott S, Lübke A, Mohme M, Westphal M
Journal of neurosurgery. Case lessons. 2023;6(25):.

Cavernous Malformations and Hemangioblastomas of the Spinal Cord Show Distinct Differences in Clinical Course - A Retrospective Single-Center Analysis of 112 Patients
Pantel T, Mende K, Mohme T, Mohme M, Viezens L, Matschke J, Westphal M, Eicker S
GLOB SPINE J. 2023 [Epub ahead of print];21925682231214363.

Impact of pre-hospital handling and initial time to cranial computed tomography on outcome in aneurysmal subarachnoid hemorrhage patients with out-of-hospital sudden cardiac arrest-a retrospective bi-centric study
Pantel T, Neulen A, Mader M, Kurz E, Piffko A, Fassl V, Westphal M, Gempt J, Ringel F, Czorlich P
FRONT CARDIOVASC MED. 2023;10:1209939.

Long-term neurocognitive function and quality of life after multimodal therapy in adult glioma patients: a prospective long-term follow-up
Pertz M, Schlömer S, Seidel C, Hentschel B, Löffler M, Schackert G, Krex D, Juratli T, Tonn J, Schnell O, Vatter H, Simon M, Westphal M, Martens T, Sabel M, Bendszus M, Dörner N, Wick A, Fliessbach K, Hoppe C, Klingner M, Felsberg J, Reifenberger G, Gramatzki D, Weller M, Schlegel U
J NEURO-ONCOL. 2023;164(2):353-366.

Corticosteroid-Dependent Leukocytosis Masks the Predictive Potential of White Blood Cells for Delayed Cerebral Ischemia and Ventriculoperitoneal Shunt Dependency in Aneurysmatic Subarachnoid Hemorrhage
Piffko A, Ricklefs F, Schweingruber N, Sauvigny T, Mader M, Mohme M, Dührsen L, Westphal M, Regelsberger J, Schmidt N, Czorlich P
J CLIN MED. 2023;12(3):.

Impact of the SARS-CoV-2 pandemic on the survival of patients with high-grade glioma and best practice recommendations
Vogel M, Wagner A, Gempt J, Krenzlin H, Zeyen T, Drexler R, Voss M, Nettekoven C, Abboud T, Mielke D, Rohde V, Timmer M, Goldbrunner R, Steinbach J, Dührsen L, Westphal M, Herrlinger U, Ringel F, Meyer B, Combs S
SCI REP-UK. 2023;13(1):2766.

P-139 Distinct neural mechanisms of deep brain stimulation and medication on improving predictive timing functions in patients with advanced Parkinson’s disease
Wang P, Gulberti A, Schneider T, Hamel W, Buhmann C, Köppen J, Gerloff C, Westphal M, Moll C, Engel A
CLIN NEUROPHYSIOL. 2023;148:e70-e71.

Skull Base Meningiomas
Westphal M, Saladino A, Tatagiba M
2023. Biological and Clinical Landscape of Meningiomas. Zadeh G, Goldbrunner R, Krischek B, Nassiri F (eds.). 1. ed. Cham: Springer Nature Switzerland AG, 47-68.

The Comprehensive Complication Index (CCI) as a Measure of Postoperative Morbidity and Neurological Outcome after Elective Intracranial Surgery
Drexler R, Ricklefs F, Pantel T, Göttsche J, Westphal M, Dührsen L
J NEUROL SURG PART A. 2022 [Epub ahead of print].

Aneurysm Location Affects Clinical Course and Mortality in Patients With Subarachnoid Hemorrhage
Göttsche J, Piffko A, Pantel T, Westphal M, Dührsen L, Czorlich P, Sauvigny T
FRONT NEUROL. 2022;13:.

Experiences with a 3D4K digital exoscope system (ORBEYE) in a wide range of neurosurgical procedures
Göttsche J, Piffko A, Pantel T, Westphal M, Flitsch J, Ricklefs F, Regelsberger J, Dührsen L
J NEUROL SURG PART A. 2022;83(6):596-601.

Hyperoxia is Dose-Dependently Associated with an Increase of Unfavorable Outcomes in Ventilated Patients with Aneurysmal Subarachnoid Hemorrhage: A Retrospective Cohort Study
Grensemann J, Mader M, Westphal M, Kluge S, Czorlich P
NEUROCRIT CARE. 2022;37(2):523-530.

The Impact of Surgery-Related Muscle Injury on Prevalence and Characteristics of Acute Postcraniotomy Headache - A Prospective Consecutive Case Series
Huckhagel T, Westphal M, Klinger R
J NEUROL SURG PART A. 2022;83(3):242-251.

Diffusion tensor imaging changes in patients with glioma-associated seizures
Mader M, Deuter D, Sauvigny T, Borchert P, Faizy T, Bester M, Westphal M, Rosengarth K, Schmidt N, Sedlacik J, Dührsen L
J NEURO-ONCOL. 2022;160(2):311-320.

Traumatic brain injury with concomitant injury to the spleen - characteristics and mortality of a high-risk trauma cohort from the TraumaRegister DGU®
Mader M, Lefering R, Westphal M, Maegele M, Czorlich P
EUR J TRAUMA EMERG S. 2022;48(6):4451–4459.

Single-Center Experience Using a 3D4K Digital Operating Scope System for Aneurysm Surgery
Pantel T, Drexler R, Göttsche J, Piffko A, Westphal M, Regelsberger J, Dührsen L
OPER NEUROSURG. 2022;22(6):433-439.

Clinical determinants impacting overall survival of patients with operable brain metastases from non-small cell lung cancer
Piffko A, Asey B, Dührsen L, Ristow I, Salamon J, Wikman H, Maire C, Lamszus K, Westphal M, Sauvigny T, Mohme M
FRONT ONCOL. 2022;12:.

DNA Methylation subclass Receptor Tyrosine Kinase II (RTK II) is predictive for seizure development in glioblastoma patients
Ricklefs F, Drexler R, Wollmann K, Eckhardt A, Heiland D, Sauvigny T, Maire C, Lamszus K, Westphal M, Schüller U, Dührsen L
NEURO-ONCOLOGY. 2022;24(11):1886-1897.

Genetic and epigenetic profiling identifies two distinct classes of spinal meningiomas
Ricklefs F, Fita K, Mohme M, Mawrin C, Rahmanzade R, Sahm F, Dührsen L, Göbel C, Lamszus K, Westphal M, Schüller U, Eicker S
ACTA NEUROPATHOL. 2022;144(5):1057-1059.

Diagnostic potential of extracellular vesicles in meningioma patients
Ricklefs F, Maire C, Wollmann K, Dührsen L, Fita K, Sahm F, Herold-Mende C, von Deimling A, Kolbe K, Holz M, Bergmann L, Fuh M, Schlüter H, Alawi M, Reimer R, Sven P, Glatzel M, Westphal M, Lamszus K
NEURO-ONCOLOGY. 2022;24(12):2078-2090.

A recurrent machine learning model predicts intracranial hypertension in neurointensive care patients
Schweingruber N, Mader M, Wiehe A, Röder F, Göttsche J, Kluge S, Westphal M, Czorlich P, Gerloff C
BRAIN. 2022;145(8):2910-2919.

Combined Subthalamic and Nigral Stimulation Modulates Temporal Gait Coordination and Cortical Gait-Network Activity in Parkinson's Disease: STN+SN DBS Modulates Parkinsonian Gait-Networks
Wagner J, Schaper M, Hamel W, Westphal M, Gerloff C, Engel A, Moll C, Gulberti A, Pötter-Nerger M
FRONT HUM NEUROSCI. 2022;16:.

Circulating tumor cells and extracellular vesicles as liquid biopsy markers in neuro-oncology: prospects and limitations
Westphal M, Pantel K, Ricklefs F, Maire C, Riethdorf S, Mohme M, Wikman H, Lamszus K
NEURO-ONCOL ADV. 2022;4(Suppl 2):ii45-ii52.

Enhancing Safety in Epilepsy Surgery (EASINESS): Study Protocol for a Retrospective, Multicenter, Open Registry
Drexler R, Ben-Haim S, Bien C, Borger V, Cardinale F, Carpentier A, Cendes F, Chandra S, Clusmann H, Colon A, de Curtis M, Delev D, Didato G, Dührsen L, Farah J, Guenot M, Ghatan S, Haegelen C, Hamer H, Hauptmann J, Jeffree R, Kalbhenn T, Kegele J, Krayenbühl N, Lang J, Mathon B, Naros G, Onken J, Panov F, Raftopoulos C, Ricklefs F, Rijkers K, Rizzi M, Rössler K, Schijns O, Schneider U, Spyrantis A, Strzelczyk A, Stodieck S, Tripathi M, Vadera S, Alonso-Vanegas M, Vaz J, Wellmer J, Wehner T, Westphal M, Sauvigny T
FRONT NEUROL. 2021;12:.

Cranial bone flap resorption-pathological features and their implications for clinical treatment
Göttsche J, Mende K, Schram A, Westphal M, Amling M, Regelsberger J, Sauvigny T, Hahn M
NEUROSURG REV. 2021;44(4):2253-2260.

Safety and Clinical Effects of Switching From Intravenous to Oral Nimodipine Administration in Aneurysmal Subarachnoid Hemorrhage
Göttsche J, Schweingruber N, Groth J, Gerloff C, Westphal M, Czorlich P
FRONT NEUROL. 2021;12:.

Telomerase reverse transcriptase promoter mutation- and O6-methylguanine DNA methyltransferase promoter methylation-mediated sensitivity to temozolomide in isocitrate dehydrogenase-wild-type glioblastoma: is there a link?
Gramatzki D, Felsberg J, Hentschel B, Wolter M, Schackert G, Westphal M, Regli L, Thon N, Tatagiba M, Wick W, Schlegel U, Krex D, Matschke J, Roth P, Suresh M, Kamp M, Rushing E, Pietsch T, von Deimling A, Sabel M, Loeffler M, Weller M, Reifenberger G
EUR J CANCER. 2021;147:84-94.

Carbon fiber-reinforced PEEK versus titanium implants - an in vitro comparison of susceptibility artifacts in CT and MR imaging
Krätzig T, Mende K, Mohme M, Kniep H, Dreimann M, Stangenberg M, Westphal M, Gauer T, Eicker S
NEUROSURG REV. 2021;44(4):2163-2170.

Bacterial adhesion characteristics on implant materials for intervertebral cages: titanium or PEEK for spinal infections?
Krätzig T, Mende K, Mohme M, von Kroge S, Stangenberg M, Dreimann M, Westphal M, Weisselberg S, Eicker S
EUR SPINE J. 2021;30(6):1774-1782.

CD74 and CD44 Expression on CTCs in Cancer Patients with Brain Metastasis
Loreth D, Schuette M, Zinke J, Mohme M, Piffko A, Schneegans S, Stadler J, Janning M, Loges S, Joosse S, Lamszus K, Westphal M, Müller V, Glatzel M, Matschke J, Gebhardt C, Schneider S, Belczacka I, Volkmer B, Greinert R, Yaspo M, Harter P, Pantel K, Wikman H
INT J MOL SCI. 2021;22(13):.

Integrated Molecular-Morphologic Meningioma Classification: A Multicenter Retrospective Analysis, Retrospectively and Prospectively Validated
Maas S, Stichel D, Hielscher T, Sievers P, Berghoff A, Schrimpf D, Sill M, Euskirchen P, Blume C, Patel A, Dogan H, Reuss D, Dohmen H, Stein M, Reinhardt A, Suwala A, Wefers A, Baumgarten P, Ricklefs F, Rushing E, Bewerunge-Hudler M, Ketter R, Schittenhelm J, Jaunmuktane Z, Leu S, Greenway F, Bridges L, Jones T, Grady C, Serrano J, Golfinos J, Sen C, Mawrin C, Jungk C, Hänggi D, Westphal M, Lamszus K, Etminan N, Jungwirth G, Herold-Mende C, Unterberg A, Harter P, Wirsching H, Neidert M, Ratliff M, Platten M, Snuderl M, Aldape K, Brandner S, Hench J, Frank S, Pfister S, Jones D, Reifenberger G, Acker T, Wick W, Weller M, Preusser M, von Deimling A, Sahm F
J CLIN ONCOL. 2021;39(34):3839-3852.

Intrathecal and systemic alterations of L-arginine metabolism in patients after intracerebral hemorrhage
Mader M, Böger R, Appel D, Schwedhelm E, Haddad M, Mohme M, Lamszus K, Westphal M, Czorlich P, Hannemann J
J CEREBR BLOOD F MET. 2021;41(8):1964-1977.

The faster the better? Time to first CT scan after admission in moderate-to-severe traumatic brain injury and its association with mortality
Mader M, Rotermund R, Lefering R, Westphal M, Maegele M, Czorlich P
NEUROSURG REV. 2021;44(5):2697–2706.

Genome-wide methylation profiling of glioblastoma cell-derived extracellular vesicle DNA allows tumor classification
Maire C, Fuh M, Kaulich K, Fita K, Stevic I, Heiland D, Welsh J, Jones J, Görgens A, Ricklefs T, Dührsen L, Sauvigny T, Joosse S, Reifenberger G, Pantel K, Glatzel M, Miklosi A, Felce J, Caselli M, Pereno V, Reimer R, Schlüter H, Westphal M, Schüller U, Lamszus K, Ricklefs F
NEURO-ONCOLOGY. 2021;23(7):1087-1099.

Intraoperative blood loss in oncological spine surgery
Mohme M, Mende K, Pantel T, Viezens L, Westphal M, Eicker S, Dreimann M, Krätzig T, Stangenberg M
NEUROSURG FOCUS. 2021;50(5):E14.

Association of COVID-19 with Intracranial Hemorrhage during Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome: A 10-Year Retrospective Observational Study
Pantel T, Roedl K, Jarczak D, Yu Y, Frings D, Sensen B, Pinnschmidt H, Bernhardt A, Cheng B, Lettow I, Westphal M, Czorlich P, Kluge S, Fischer M
J CLIN MED. 2021;11(1):.

EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood
Weller M, van den Bent M, Preusser M, Le Rhun E, Tonn J, Minniti G, Bendszus M, Balana C, Chinot O, Dirven L, French P, Hegi M, Jakola A, Platten M, Roth P, Rudà R, Short S, Smits M, Taphoorn M, von Deimling A, Westphal M, Soffietti R, Reifenberger G, Wick W
NAT REV CLIN ONCOL. 2021;18(3):170-186.

Refining the treatment of spinal cord lesions: experience from 500 cases
Westphal M, Mende K, Eicker S
NEUROSURG FOCUS. 2021;50(5):.

Parkinson's disease uncovers an underlying sensitivity of subthalamic nucleus neurons to beta-frequency cortical input in vivo
Baaske M, Kormann E, Holt A, Gulberti A, McNamara C, Pötter-Nerger M, Westphal M, Engel A, Hamel W, Brown P, Moll C, Sharott A
NEUROBIOL DIS. 2020;146(146):105119.

Discovery of Targetable Genetic Alterations in NSCLC Patients with Different Metastatic Patterns Using a MassARRAY-Based Circulating Tumor DNA Assay
Belloum Y, Janning M, Mohme M, Simon R, Kropidlowski J, Sartori A, Irwin D, Westphal M, Lamszus K, Loges S, Riethdorf S, Pantel K, Wikman H
CELLS-BASEL. 2020;9(11):.

FOCAD loss impacts microtubule assembly, G2/M progression and patient survival in astrocytic gliomas
Brand F, Förster A, Christians A, Bucher M, Thomé C, Raab M, Westphal M, Pietsch T, von Deimling A, Reifenberger G, Claus P, Hentschel B, Weller M, Weber R
ACTA NEUROPATHOL. 2020;139(1):175-192.

Sex Disparities in the Self-Evaluation of Subthalamic Deep Brain Stimulation Effects on Mood and Personality in Parkinson's Disease Patients
Dietrich A, Koeppen J, Buhmann C, Pötter-Nerger M, Pinnschmidt H, Oehlwein C, Oehlwein M, Mittmann K, Gerloff C, Engel A, Westphal M, Schaper M, Hamel W, Moll C, Gulberti A
FRONT NEUROL. 2020;11:776.

Decompressive craniectomy in malignant MCA infarction in times of mechanical thrombectomy
Göttsche J, Flottmann F, Jank L, Thomalla G, Rimmele D, Czorlich P, Westphal M, Regelsberger J
ACTA NEUROCHIR. 2020;162(12):3147-3152.

A Comparison between Pediatric and Adult Patients after Cranioplasty: Aseptic Bone Resorption Causes Earlier Revision in Children
Göttsche J, Fritzsche F, Kammler G, Sauvigny T, Westphal M, Regelsberger J
J NEUROL SURG PART A. 2020;81(3):227-232.

The burden of headache following aneurysmal subarachnoid hemorrhage: a prospective single-center cross-sectional analysis
Huckhagel T, Klinger R, Schmidt N, Regelsberger J, Westphal M, Czorlich P
ACTA NEUROCHIR. 2020;162(4):893-903.

Initial pupil status is a strong predictor for in-hospital mortality after aneurysmal subarachnoid hemorrhage
Mader M, Piffko A, Dengler N, Ricklefs F, Dührsen L, Schmidt N, Regelsberger J, Westphal M, Wolf S, Czorlich P
SCI REP-UK. 2020;10(1):4764.

Glioma escape signature and clonal development under immune pressure
Maire C, Mohme M, Bockmayr M, Fita K, Riecken K, Börnigen D, Alawi M, Failla A, Kolbe K, Zapf S, Holz M, Neumann K, Dührsen L, Lange T, Fehse B, Westphal M, Lamszus K
J CLIN INVEST. 2020;130(10):5257-5271.

Local intracerebral immunomodulation using interleukin-expressing mesenchymal stem cells in glioblastoma
Mohme M, Maire C, Geumann U, Schliffke S, Dührsen L, Fita K, Akyüz N, Binder M, Westphal M, Guenther C, Lamszus K, Hermann F, Schmidt N
CLIN CANCER RES. 2020;26(11):2626-2639.

Molecular profiling of an osseous metastasis in glioblastoma during checkpoint inhibition: potential mechanisms of immune escape
Mohme M, Maire C, Schliffke S, Joosse S, Alawi M, Matschke J, Schüller U, Dierlamm J, Martens T, Pantel K, Riethdorf S, Lamszus K, Westphal M
ACTA NEUROPATHOL COM. 2020;8(1):.

Genome-wide DNA methylation profiles distinguish silent from non-silent ACTH adenomas
Ricklefs F, Fita K, Rotermund R, Piffko A, Schmid S, Capper D, Buslei R, Buchfelder M, Burkhardt T, Matschke J, Lamszus K, Westphal M, Schüller U, Flitsch J
ACTA NEUROPATHOL. 2020;140(1):95-97.

FASN Is a Biomarker Enriched in Malignant Glioma-Derived Extracellular Vesicles
Ricklefs F, Maire C, Matschke J, Dührsen L, Sauvigny T, Holz M, Kolbe K, Peine S, Herold-Mende C, Carter B, Chiocca E, Lawler S, Westphal M, Lamszus K
INT J MOL SCI. 2020;21(6):.

Exome sequencing in 38 patients with intracranial aneurysms and subarachnoid hemorrhage
Sauvigny T, Alawi M, Krause L, Renner S, Spohn M, Busch A, Kolbe V, Altmüller J, Löscher B, Franke A, Brockmann C, Lieb W, Westphal M, Schmidt N, Regelsberger J, Rosenberger G
J NEUROL. 2020;267(9):2533-2545.

Features of tumor texture influence surgery and outcome in intracranial meningioma
Sauvigny T, Ricklefs F, Hoffmann L, Schwarz R, Westphal M, Schmidt N
NEURO-ONCOL ADV. 2020;2(1):vdaa113.

Bevacizumab versus alkylating chemotherapy in recurrent glioblastoma
Seystahl K, Hentschel B, Loew S, Gramatzki D, Felsberg J, Herrlinger U, Westphal M, Schackert G, Thon N, Tatagiba M, Pietsch T, Reifenberger G, Löffler M, Wick W, Weller M
J CANCER RES CLIN. 2020;146(3):659-670.

CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas
Sievers P, Hielscher T, Schrimpf D, Stichel D, Reuss D, Berghoff A, Neidert M, Wirsching H, Mawrin C, Ketter R, Paulus W, Reifenberger G, Lamszus K, Westphal M, Etminan N, Ratliff M, Herold-Mende C, Pfister S, Jones D, Weller M, Harter P, Wick W, Preusser M, von Deimling A, Sahm F
ACTA NEUROPATHOL. 2020;140(3):409-413.

Pallidal lead placement in dystonia: leads of non-responders are contained within an anatomical range defined by responders
Zittel S, Hidding U, Trumpfheller M, Baltzer V, Gulberti A, Schaper M, Biermann M, Buhmann C, Engel A, Gerloff C, Westphal M, Stadler J, Köppen J, Pötter-Nerger M, Moll C, Hamel W
J NEUROL. 2020;267(6):1663-1671.

DNA methylation, transcriptome and genetic copy number signatures of diffuse cerebral WHO grade II/III gliomas resolve cancer heterogeneity and development
Binder H, Willscher E, Loeffler-Wirth H, Hopp L, Jones D, Pfister S, Kreuz M, Gramatzki D, Fortenbacher E, Hentschel B, Tatagiba M, Herrlinger U, Vatter H, Matschke J, Westphal M, Krex D, Schackert G, Tonn J, Schlegel U, Steiger H, Wick W, Weber R, Weller M, Loeffler M
ACTA NEUROPATHOL COM. 2019;7(1):59.

Immunologic Profiling of Mutational and Transcriptional Subgroups in Pediatric and Adult High-Grade Gliomas
Bockmayr M, Klauschen F, Maire C, Rutkowski S, Westphal M, Lamszus K, Schüller U, Mohme M
CANCER IMMUNOL RES. 2019;7(9):1401-1411.

Postoperative Nausea and Vomiting Following Craniotomy: Risk Factors and Complications in Context of Perioperative High-dose Dexamethasone Application
Burkhardt T, Czorlich P, Mende K, Treitz A, Kiefmann R, Westphal M, Schmidt N
J NEUROL SURG PART A. 2019;80(5):381-386.

Temporal evolution of beta bursts in the parkinsonian cortical and basal ganglia network
Cagnan H, Mallet N, Moll C, Gulberti A, Holt A, Westphal M, Gerloff C, Engel A, Hamel W, Magill P, Brown P, Sharott A
P NATL ACAD SCI USA. 2019;116(32):16095-16104.

Operative versus non-operative treatment of traumatic brain injuries in patients 80 years of age or older
Czorlich P, Mader M, Emami P, Westphal M, Lefering R, Hoffmann M
NEUROSURG REV. 2019;43(5):.

Preclinical analysis of human mesenchymal stem cells: tumor tropism and therapeutic efficiency of local HSV-TK suicide gene therapy in glioblastoma
Dührsen L, Hartfuß S, Hirsch D, Geiger S, Maire C, Sedlacik J, Guenther C, Westphal M, Lamszus K, Hermann F, Schmidt N
ONCOTARGET. 2019;10(58):6049-6061.

Seizures as presenting symptom in patients with glioblastoma
Dührsen L, Sauvigny T, Ricklefs F, Mende K, Schaper M, Matschke J, Goebell E, Westphal M, Martens T
EPILEPSIA. 2019;60(1):149-154.

Observed versus expected mortality in pediatric patients intubated in the field with Glasgow Coma Scale scores <9
Emami P, Czorlich P, Fritzsche F, Westphal M, Rueger J, Lefering R, Hoffmann M
EUR J TRAUMA EMERG S. 2019;45(5):769-776.

The differential role of subthalamic and nigral neurons in gait control in Parkinson's disease patients
Gulberti A, Horn A, Wagner J, Schaper M, Köppen J, Buhmann C, Sharott A, Westphal M, Engel A, Gerloff C, Hamel W, Moll C, Pötter-Nerger M
MOVEMENT DISORD. 2019;2019(34):503.

Modulation of specific components of sleep disturbances by simultaneous subthalamic and nigral stimulation in Parkinson's disease
Hidding U, Gulberti A, Pflug C, Choe C, Horn A, Prilop L, Braaß H, Fründt O, Buhmann C, Weiss D, Westphal M, Engel A, Gerloff C, Köppen J, Hamel W, Moll C, Pötter-Nerger M
PARKINSONISM RELAT D. 2019;62:141-147.

Phase-dependent suppression of beta oscillations in Parkinson's disease patients
Holt A, Kormann E, Gulberti A, Pötter-Nerger M, McNamara C, Cagnan H, Baaske M, Little S, Köppen J, Buhmann C, Westphal M, Gerloff C, Engel A, Brown P, Hamel W, Moll C, Sharott A
J NEUROSCI. 2019;39(6):1119-1134.

Identification of KIF11 As a Novel Target in Meningioma
Jungwirth G, Yu T, Moustafa M, Rapp C, Warta R, Jungk C, Sahm F, Dettling S, Zweckberger K, Lamszus K, Senft C, Loehr M, Keßler A, Ketter R, Westphal M, Debus J, von Deimling A, Simon M, Unterberg A, Abdollahi A, Herold-Mende C
CANCERS. 2019;11(4):.

The role of frameless stereotactic biopsy in contemporary neuro-oncology: molecular specifications and diagnostic yield in biopsied glioma patients
Mader M, Rotermund R, Martens T, Westphal M, Matschke J, Abboud T
J NEURO-ONCOL. 2019;141(1):183-194.

Synchronised spiking activity underlies phase amplitude coupling in the subthalamic nucleus of Parkinson's disease patients
Meidahl A, Moll C, van Wijk B, Gulberti A, Tinkhauser G, Westphal M, Engel A, Hamel W, Brown P, Sharott A
NEUROBIOL DIS. 2019;127:101-113.

Immune Characterization in Aneurysmal Subarachnoid Hemorrhage Reveals Distinct Monocytic Activation and Chemokine Patterns
Mohme M, Sauvigny T, Mader M, Schweingruber N, Maire C, Rünger A, Ricklefs F, Regelsberger J, Schmidt N, Westphal M, Lamszus K, Tolosa E, Czorlich P
TRANSL STROKE RES. 2019.

Cytotoxic T Cells and their Activation Status are Independent Prognostic Markers in Meningiomas
Rapp C, Dettling S, Liu F, Ull A, Warta R, Jungk C, Roesch S, Mock A, Sahm F, Schmidt M, Jungwirth G, Zweckberger K, Lamszus K, Gousias K, Kessler A, Grabe N, Loehr M, Ketter R, Urbschat S, Senft C, Westphal M, Abdollahi A, Debus J, von Deimling A, Unterberg A, Simon M, Herold-Mende C
CLIN CANCER RES. 2019;25(17):5260-5270.

Relapse of a group 4 medulloblastoma after 18 years as proven by histology and DNA methylation profiling
Ricklefs F, Fritzsche F, Winkler B, Meissner B, Dührsen L, Westphal M, Rutkowski S, Martens T, Schüller U
CHILD NERV SYST. 2019;35(6):1029-1033.

Imaging flow cytometry facilitates multiparametric characterization of extracellular vesicles in malignant brain tumours
Ricklefs F, Maire C, Reimer R, Dührsen L, Kolbe K, Holz M, Schneider E, Rissiek A, Babayan A, Hille C, Pantel K, Krasemann S, Glatzel M, Heiland D, Flitsch J, Martens T, Schmidt N, Peine S, Breakefield X, Lawler S, Chiocca E, Fehse B, Giebel B, Görgens A, Westphal M, Lamszus K
J EXTRACELL VESICLES. 2019;8(1):1588555.

Clonality of circulating tumor cells in breast cancer brain metastasis patients
Riebensahm C, Joosse S, Mohme M, Hanssen A, Matschke J, Goy Y, Witzel I, Lamszus K, Kropidlowski J, Petersen C, Kolb-Kokocinski A, Sauer S, Borgmann K, Glatzel M, Müller V, Westphal M, Riethdorf S, Pantel K, Wikman H
BREAST CANCER RES. 2019;21(1):101.

Rate and risk factors for a hyperactivity delirium in patients with aneurysmal subarachnoid haemorrhage
Sauvigny T, Mohme M, Grensemann J, Dührsen L, Regelsberger J, Kluge S, Schmidt N, Westphal M, Czorlich P
NEUROSURG REV. 2019;42(2):481-488.

Early clinical course after aneurysmal subarachnoid hemorrhage: comparison of patients treated with Woven EndoBridge, microsurgical clipping, or endovascular coiling
Sauvigny T, Nawka M, Schweingruber N, Mader M, Regelsberger J, Schmidt N, Westphal M, Czorlich P
ACTA NEUROCHIR. 2019;161(9):1763-1773.

EGFR and HER3 expression in circulating tumor cells and tumor tissue from non-small cell lung cancer patients
Scharpenseel H, Hanssen A, Loges S, Mohme M, Bernreuther C, Peine S, Lamszus K, Goy Y, Petersen C, Westphal M, Glatzel M, Riethdorf S, Pantel K, Wikman H
SCI REP-UK. 2019;9(1):7406.

DNA methylation-based classification of central nervous system tumours
Capper D, Jones D, Sill M, Hovestadt V, Schrimpf D, Sturm D, Koelsche C, Sahm F, Chavez L, Reuss D, Kratz A, Wefers A, Huang K, Pajtler K, Schweizer L, Stichel D, Olar A, Engel N, Lindenberg K, Harter P, Braczynski A, Plate K, Dohmen H, Garvalov B, Coras R, Hölsken A, Hewer E, Bewerunge-Hudler M, Schick M, Fischer R, Beschorner R, Schittenhelm J, Staszewski O, Wani K, Varlet P, Pages M, Temming P, Lohmann D, Selt F, Witt H, Milde T, Witt O, Aronica E, Giangaspero F, Rushing E, Scheurlen W, Geisenberger C, Rodriguez F, Becker A, Preusser M, Haberler C, Bjerkvig R, Cryan J, Farrell M, Deckert M, Hench J, Frank S, Serrano J, Kannan K, Tsirigos A, Brück W, Hofer S, Brehmer S, Seiz-Rosenhagen M, Hänggi D, Hans V, Rozsnoki S, Hansford J, Kohlhof P, Kristensen B, Lechner M, Lopes B, Mawrin C, Ketter R, Kulozik A, Khatib Z, Heppner F, Koch A, Jouvet A, Keohane C, Mühleisen H, Mueller W, Pohl U, Prinz M, Benner A, Zapatka M, Gottardo N, Driever P, Kramm C, Müller H, Rutkowski S, von Hoff K, Frühwald M, Gnekow A, Fleischhack G, Tippelt S, Calaminus G, Monoranu C, Perry A, Jones C, Jacques T, Radlwimmer B, Gessi M, Pietsch T, Schramm J, Schackert G, Westphal M, Reifenberger G, Wesseling P, Weller M, Collins V, Blümcke I, Bendszus M, Debus J, Huang A, Jabado N, Northcott P, Paulus W, Gajjar A, Robinson G, Taylor M, Jaunmuktane Z, Ryzhova M, Platten M, Unterberg A, Wick W, Karajannis M, Mittelbronn M, Acker T, Hartmann C, Aldape K, Schüller U, Buslei R, Lichter P, Kool M, Herold-Mende C, Ellison D, Hasselblatt M, Snuderl M, Brandner S, Korshunov A, von Deimling A, Pfister S
NATURE. 2018;555(7697):469-474.

Intraocular pressure during neurosurgical procedures in context of head position and loss of cerebrospinal fluid
Czorlich P, Krätzig T, Kluge N, Skevas C, Knospe V, Spitzer M, Dreimann M, Mende K, Westphal M, Eicker S
J NEUROSURG. 2018;131(1):271-280.

Impact of focal cortical dysplasia Type IIIa on seizure outcome following anterior mesial temporal lobe resection for the treatment of epilepsy
Dührsen L, Sauvigny T, House P, Stodieck S, Holst B, Matschke J, Schön G, Westphal M, Martens T
J NEUROSURG. 2018;128(6):1668-1673.

Towards unambiguous reporting of complications related to deep brain stimulation surgery: A retrospective single-center analysis and systematic review of the literature
Engel K, Huckhagel T, Gulberti A, Pötter-Nerger M, Vettorazzi E, Hidding U, Choe C, Zittel S, Braaß H, Ludewig P, Schaper M, Krajewski K, Oehlwein C, Mittmann K, Engel A, Gerloff C, Westphal M, Moll C, Buhmann C, Köppen J, Hamel W
PLOS ONE. 2018;13(8):e0198529.

Frequency of Circulating Tumor Cells (CTC) in Patients with Brain Metastases: Implications as a Risk Assessment Marker in Oligo-Metastatic Disease
Hanssen A, Riebensahm C, Mohme M, Joosse S, Velthaus J, Berger L, Bernreuther C, Glatzel M, Loges S, Lamszus K, Westphal M, Riethdorf S, Pantel K, Wikman H
CANCERS. 2018;10(12):E527.

The secreted glycolytic enzyme GPI/AMF stimulates glioblastoma cell migration and invasion in an autocrine fashion but can have anti-proliferative effects
Kathagen-Buhmann A, Maire C, Weller J, Schulte A, Matschke J, Holz M, Ligon K, Glatzel M, Westphal M, Lamszus K
NEURO-ONCOLOGY. 2018;20(12):1594-1605.

Extensive spinal adhesive arachnoiditis after extradural spinal infection - spinal dura mater is no barrier to inflammation
Krätzig T, Dreimann M, Mende K, Königs I, Westphal M, Eicker S
WORLD NEUROSURG. 2018;116:E1194-E1203.

Intrathecal penetration of meropenem and vancomycin administered by continuous infusion in patients suffering from ventriculitis-a retrospective analysis
Mader M, Czorlich P, König C, Fuhrmann V, Kluge S, Westphal M, Grensemann J
ACTA NEUROCHIR. 2018;160(11):2099-2105.

Rate and impact of multidrug-resistant organisms in patients with aneurysmal subarachnoid hemorrhage
Mader M, Grensemann J, Kluge S, Westphal M, Czorlich P
ACTA NEUROCHIR. 2018;160(10):2049-2054.

Tectal gliomas: Assessment of malignant progression, clinical management, and quality of life in a supposedly benign neoplasm
Mohme M, Fritzsche F, Mende K, Matschke J, Löbel U, Kammler G, Westphal M, Emami P, Martens T
NEUROSURG FOCUS. 2018;44(6):E15.

Immunophenotyping of Newly Diagnosed and Recurrent Glioblastoma Defines Distinct Immune Exhaustion Profiles in Peripheral and Tumor-infiltrating Lymphocytes
Mohme M, Schliffke S, Maire C, Rünger A, Glau L, Mende K, Matschke J, Gehbauer C, Akyüz N, Zapf S, Holz M, Schaper M, Martens T, Schmidt N, Peine S, Westphal M, Binder M, Tolosa E, Lamszus K
CLIN CANCER RES. 2018;24(17):4187-4200.

The natural HLA ligandome of glioblastoma stem-like cells: antigen discovery for T cell-based immunotherapy
Neidert M, Kowalewski D, Silginer M, Kapolou K, Backert L, Freudenmann L, Peper J, Marcu A, Wang S, Walz J, Wolpert F, Rammensee H, Henschler R, Lamszus K, Westphal M, Roth P, Regli L, Stevanović S, Weller M, Eisele G
ACTA NEUROPATHOL. 2018;135(6):923-938.

Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles
Ricklefs F, Alayo Q, Krenzlin H, Mahmoud A, Speranza M, Nakashima H, Hayes J, Lee K, Balaj L, Passaro C, Krasemann S, Carter B, Chen C, Steed T, Treiber J, Rodig S, Yang K, Nakano I, Lee H, Weissleder R, Breakefield X, Godlweski J, Westphal M, Lamszus K, Freeman G, Bronisz A, Lawler S, Chiocca E
SCI ADV. 2018;4(3):eaar2766.

Intracranial pressure in patients undergoing decompressive craniectomy: new perspective on thresholds
Sauvigny T, Göttsche J, Czorlich P, Vettorazzi E, Westphal M, Regelsberger J
J NEUROSURG. 2018;128(3):819-827.

Spatio-temporal dynamics of cortical drive to human subthalamic nucleus neurons in Parkinson's disease
Sharott A, Gulberti A, Hamel W, Köppen J, Münchau A, Buhmann C, Pötter-Nerger M, Westphal M, Gerloff C, Moll C, Engel A
NEUROBIOL DIS. 2018;112:49-62.

How does it feel to be operated on the brain? Perceived intraoperative stress of movement disorder patients undergoing awake deep brain stimulation surgery
Sieger J, Gulberti A, Köppen J, Pinnschmidt H, Nitzschke R, Schaper M, Braaß H, Buhmann C, Choe C, Hidding U, Zittel S, Engel A, Mehnert A, Gerloff C, Westphal M, Pötter-Nerger M, Hamel W, Moll C
2018. The many faces of Parkinson’s disease – Motor and non ‐ motor symptoms from prodromal to advanced disease stages. .

Best practices for the use of intracerebroventricular drug delivery devices
Slavc I, Cohen-Pfeffer J, Gururangan S, Krauser J, Lim D, Maldaun M, Schwering C, Shaywitz A, Westphal M
MOL GENET METAB. 2018;124(3):184-188.

Why Does Threshold Level Change in Transcranial Motor-evoked Potentials During Surgery for Supratentorial Lesions?
Abboud T, Huckhagel T, Stork J, Hamel W, Schwarz C, Vettorazzi E, Westphal M, Martens T
J NEUROSURG ANESTH. 2017;29(4):393-399.

Prognostic value of early S100B protein and Neuron-specific Enolase in patients with poor grade aneurysmal subarachnoid hemorrhage, a pilot study
Abboud T, Mende K, Jung R, Czorlich P, Vettorazzi E, Priefler M, Kluge S, Westphal M, Regelsberger J
WORLD NEUROSURG. 2017;108:669-675.

Morphology of Ruptured and Unruptured Intracranial Aneurysms
Abboud T, Rustom J, Bester M, Czorlich P, Vettorazzi E, Pinnschmidt H, Westphal M, Regelsberger J
WORLD NEUROSURG. 2017;99:610-617.

Adverse events in deep brain stimulation: A retrospective long-term analysis of neurological, psychiatric and other occurrences
Buhmann C, Huckhagel T, Engel K, Gulberti A, Hidding U, Poetter-Nerger M, Goerendt I, Ludewig P, Braass H, Choe C, Krajewski K, Oehlwein C, Mittmann K, Engel A, Gerloff C, Westphal M, Köppen J, Moll C, Hamel W
PLOS ONE. 2017;12(7):e0178984.

Body-Mass-Index > 35 as an Independent Predictor of Mortality in Severe Traumatic Brain Injury
Czorlich P, Dreimann M, Emami P, Westphal M, Lefering R, Hoffmann M
WORLD NEUROSURG. 2017;107:515-521.

Impact of dexamethasone in patients with aneurysmal subarachnoid haemorrhage
Czorlich P, Sauvigny T, Ricklefs F, Abboud T, Nierhaus A, Vettorazzi E, Reuter D, Regelsberger J, Westphal M, Schmidt N
EUR J NEUROL. 2017;24(4):645-651.

A 55-Year-Old Woman with Year-Long Headache and Dizziness
Dührsen L, Matschke J, Westphal M
BRAIN PATHOL. 2017;27(1):111-112.

Impact of Glasgow Coma Scale score and pupil parameters on mortality rate and outcome in pediatric and adult severe traumatic brain injury: a retrospective, multicenter cohort study
Emami P, Czorlich P, Fritzsche F, Westphal M, Rueger J, Lefering R, Hoffmann M
J NEUROSURG. 2017;126(3):760-767.

Maternal Aneurysmal Subarachnoid Hemorrhage During Pregnancy as an Interdisciplinary Task
Fritzsche F, Regelsberger J, Schmidt N, Müller J, Buhk J, Diemert A, Westphal M, Martens T
Z GEBURTSH NEONATOL. 2017;221(6):276-282.

Impact of combined subthalamic nucleus and substantia nigra stimulation on neuropsychiatric symptoms in Parkinson’s disease patients
Hidding U, Gulberti A, Horn A, Buhmann C, Hamel W, Köppen J, Westphal M, Engel A, Gerloff C, Weiss D, Moll C, Pötter-Nerger M
PARKINSONS DIS-US. 2017;2017:7306192.

PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression
Hohensee I, Chuang H, Grottke A, Werner S, Schulte A, Horn S, Lamszus K, Bartkowiak K, Witzel I, Westphal M, Matschke J, Glatzel M, Jücker M, Pukrop T, Pantel K, Wikman H
ONCOTARGET. 2017;8(4):6155-6168.

Somatosensory evoked potentials in patients with high-grade aneurysmal subarachnoid hemorrhage
Mende K, Gelderblom M, Schwarz C, Czorlich P, Schmidt N, Vettorazzi E, Regelsberger J, Westphal M, Abboud T
NEUROSURG FOCUS. 2017;43(5):E17.

Keyhole approaches to intradural pathologies
Mende K, Krätzig T, Mohme M, Westphal M, Eicker S
NEUROSURG FOCUS. 2017;43(2):E5.

Pituicytoma-An outlook on possible targeted therapies
Mende K, Matschke J, Burkhardt T, Saeger W, Buslei R, Buchfelder M, Fahlbusch R, Westphal M, Flitsch J
CNS NEUROSCI THER. 2017;23(7):620-626.

Optical Barcoding for Single-Clone Tracking to Study Tumor Heterogeneity
Mohme M, Maire C, Riecken K, Zapf S, Aranyossy T, Westphal M, Lamszus K, Fehse B
MOL THER. 2017;25(3):621-633.

Circulating Tumour Cell Release after Cement Augmentation of Vertebral Metastases
Mohme M, Riethdorf S, Dreimann M, Werner S, Maire C, Joosse S, Bludau F, Mueller V, Neves R, Stoecklein N, Lamszus K, Westphal M, Pantel K, Wikman H, Eicker S
SCI REP-UK. 2017;7(1):7196.

Irreversible Total Loss of Brain Function and Organ Donation in Patients with Aneurysmal Subarachnoid Hemorrhage
Mohme M, Sauvigny T, Grensemann J, Söffker G, Kluge S, Westphal M, Czorlich P
WORLD NEUROSURG. 2017;105:492-497.

DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis
Sahm F, Schrimpf D, Stichel D, Jones D, Hielscher T, Schefzyk S, Okonechnikov K, Koelsche C, Reuss D, Capper D, Sturm D, Wirsching H, Berghoff A, Baumgarten P, Kratz A, Huang K, Wefers A, Hovestadt V, Sill M, Ellis H, Kurian K, Okuducu A, Jungk C, Drueschler K, Schick M, Bewerunge-Hudler M, Mawrin C, Seiz-Rosenhagen M, Ketter R, Simon M, Westphal M, Lamszus K, Becker A, Koch A, Schittenhelm J, Rushing E, Collins V, Brehmer S, Chavez L, Platten M, Hänggi D, Unterberg A, Paulus W, Wick W, Pfister S, Mittelbronn M, Preusser M, Herold-Mende C, Weller M, von Deimling A
LANCET ONCOL. 2017;18(5):682-694.

EGFR as a Target for Glioblastoma Treatment: An Unfulfilled Promise
Westphal M, Maire C, Lamszus K
CNS DRUGS. 2017;31(9):723-735.

A novel threshold criterion in transcranial motor evoked potentials during surgery for gliomas close to the motor pathway
Abboud T, Schaper M, Dührsen L, Schwarz C, Schmidt N, Westphal M, Martens T
J NEUROSURG. 2016;125(4):795-802.

Surgical management of pituitary metastases
Burkhardt T, Henze M, Kluth L, Westphal M, Schmidt N, Flitsch J
PITUITARY. 2016;19(1):11-18.

From Abstract to Publication in a Peer-Reviewed Journal: Evaluation of the 63rd Annual Meeting of the German Society of Neurosurgery
Czorlich P, Regelsberger J, Meixensberger J, Westphal M, Eicker S
J NEUROL SURG PART A. 2016;77(1):46-51.

Terson's syndrome - Pathophysiologic considerations of an underestimated concomitant disease in aneurysmal subarachnoid hemorrhage
Czorlich P, Skevas C, Knospe V, Vettorazzi E, Westphal M, Regelsberger J
J CLIN NEUROSCI. 2016;33:182-186.

Meninigiomas of the Craniocervical Junction - A Distinctive Subgroup of Meningiomas
Dührsen L, Emami P, Matschke J, Abboud T, Westphal M, Regelsberger J
PLOS ONE. 2016;11(4):e0153405.

STN-DBS Reduces Saccadic Hypometria but Not Visuospatial Bias in Parkinson's Disease Patients
Fischer P, Ossandón J, Keyser J, Gulberti A, Wilming N, Hamel W, Köppen J, Buhmann C, Westphal M, Gerloff C, Moll C, Engel A, König P
FRONT BEHAV NEUROSCI. 2016;10:85.

Epidermal growth factor receptor overexpression is common and not correlated to gene copy number in ependymoma
Friedrich C, von Bueren A, Kolevatova L, Bernreuther C, Grob T, Sepulveda-Falla D, van den Boom L, Westphal M, Simon R, Glatzel M
CHILD NERV SYST. 2016;32(2):281-90.

Effects of levodopa, low-frequency and high-frequency STN-DBS on auditory-motor synchronization in Parkinson’s disease
Gulberti A, Schneider T, Galindo-Leon E, Pino A, Hamel W, Buhmann C, Pötter-Nerger M, Köppen J, Westphal M, Gerloff C, Engel A, Moll C
2016. International DBS Symposium Clinical Research Group KFO 247. .

Histone Deacetylase Inhibitors Resensitize EGFR/EGFRvIII-Overexpressing, Erlotinib-Resistant Glioblastoma Cells to Tyrosine Kinase Inhibition
Liffers K, Kolbe K, Westphal M, Lamszus K, Schulte A
TARGET ONCOL. 2016;11(1):29-40.

Secretory Meningiomas: Characteristic Features and Clinical Management of a Unique Subgroup
Mohme M, Emami P, Matschke J, Regelsberger J, Westphal M, Eicker S
NEUROSURG CLIN N AM. 2016;27(2):181-7.

Secretory Meningiomas: Increased Prevalence of Seizures Secondary to Edema Formation in a Rare Histologic Subtype
Mohme M, Emami P, Regelsberger J, Matschke J, Lamszus K, Westphal M, Eicker S
WORLD NEUROSURG. 2016;92:418-25.

Angioarchitectural risk factors for hemorrhage and clinical long-term outcome in pediatric patients with cerebral arteriovenous malformations
Reitz M, von Spreckelsen N, Vettorazzi E, Burkhardt T, Grzyska U, Fiehler J, Schmidt N, Westphal M, Regelsberger J
WORLD NEUROSURG. 2016;89:540-51.

Neuropsychological performance and seizure control after subsequent anteromesial temporal lobe resection following selective amygdalohippocampectomy
Sauvigny T, Brückner K, Dührsen L, Heese O, Westphal M, Stodieck S, Martens T
EPILEPSIA. 2016;57(11):1789-1797.

New Radiologic Parameters Predict Clinical Outcome after Decompressive Craniectomy
Sauvigny T, Göttsche J, Vettorazzi E, Westphal M, Regelsberger J
WORLD NEUROSURG. 2016;88:519–525.e1.

Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade
Schmidt M, Mock A, Jungk C, Sahm F, Ull A, Warta R, Lamszus K, Gousias K, Ketter R, Roesch S, Rapp C, Schefzyk S, Urbschat S, Lahrmann B, Kessler A, Löhr M, Senft C, Grabe N, Reuss D, Beckhove P, Westphal M, von Deimling A, Unterberg A, Simon M, Herold-Mende C
ONCOTARGET. 2016;7(12):14551-68.

Serum levels of nimodipine in enteral and parenteral administration in patients with aneurysmal subarachnoid hemorrhage
Abboud T, Andresen-Streichert H, Koeppen J, Czorlich P, Dührsen L, Stenzig J, Westphal M, Regelsberger J
ACTA NEUROCHIR. 2015;157(5):763-767.

Long-term vestibulocochlear functional outcome following retro-sigmoid approach to resection of vestibular schwannoma
Abboud T, Regelsberger J, Matschke J, Jowett N, Westphal M, Dalchow C
EUR ARCH OTO-RHINO-L. 2015;273(3):719-725.

Hippocampal and cerebellar atrophy in patients with Cushing's disease
Burkhardt T, Lüdecke D, Spies L, Wittmann L, Westphal M, Flitsch J
NEUROSURG FOCUS. 2015;39(5):E5.

Intraoperative Micro-Doppler in Cerebral Arteriovenous Malformations
Burkhardt T, Siasios G, Schmidt N, Reitz M, Regelsberger J, Westphal M
J NEUROL SURG PART A. 2015;76(6):451-455.

Validation of the modified Graeb score in aneurysmal subarachnoid hemorrhage
Czorlich P, Mende C, Vettorazzi E, Regelsberger J, Westphal M, Schmidt N
ACTA NEUROCHIR. 2015;157(11):1867-72.

Impact of intraventricular hemorrhage measured by Graeb and LeRoux score on case fatality risk and chronic hydrocephalus in aneurysmal subarachnoid hemorrhage
Czorlich P, Ricklefs F, Reitz M, Vettorazzi E, Abboud T, Regelsberger J, Westphal M, Schmidt N
ACTA NEUROCHIR. 2015;157(3):409-15.

The simplified acute physiology score II to predict hospital mortality in aneurysmal subarachnoid hemorrhage
Czorlich P, Sauvigny T, Ricklefs F, Kluge S, Vettorazzi E, Regelsberger J, Westphal M, Schmidt N
ACTA NEUROCHIR. 2015;157(12):2051-2059.

Adverse events associated with deep brain stimulation surgery and ongoing treatment
Engel A, Köppen J, Buhmann C, Moll C, Huckhagel T, Westphal M, Hamel W
2015. 66th Annual Meeting of the German Society of Neurosurgery (DGNC). .

Predictive timing functions of cortical beta oscillations are impaired in Parkinson´s disease and influenced by L-DOPA and deep brain stimulation of the subthalamic nucleus
Gulberti A, Moll C, Hamel W, Buhmann C, Köppen J, Boelmans K, Zittel-Dirks S, Gerloff C, Westphal M, Schneider T, Engel A
NEUROIMAGE-CLIN. 2015;(9):436-449.

A 19-Year-Old Male with an Intraventricular Tumor Disseminated anaplastic hemangiopericytoma WHO grade III/solitary fibrous tumor, cellular type
Krajewski K, Matschke J, Humke N, Wolfgang B, Westphal M, Schmidt N
2015. BRAIN PATHOLOGY. 657-658. ed. .

Vascular events after transsylvian selective amygdalohippocampectomy and impact on epilepsy outcome
Martens T, Merkel M, Holst B, Brückner K, Lindenau M, Stodieck S, Fiehler J, Westphal M, Heese O
EPILEPSIA. 2015;55(5):763-769.

Printed peptide arrays identify prognostic TNC serumantibodies in glioblastoma patients
Mock A, Warta R, Geisenberger C, Bischoff R, Schulte A, Lamszus K, Stadler V, Felgenhauer T, Schichor C, Schwartz C, Matschke J, Jungk C, Ahmadi R, Sahm F, Capper D, Glass R, Tonn J, Westphal M, von Deimling A, Unterberg A, Bermejo J, Herold-Mende C
ONCOTARGET. 2015;6(15):13576-13590.

Synchronized cortico-subthalamic beta oscillations in Parkin-associated Parkinson's disease
Moll C, Buhmann C, Gulberti A, Fickel U, Poetter-Nerger M, Westphal M, Gerloff C, Hamel W, Engel A
CLIN NEUROPHYSIOL. 2015;126(11):2241-3.

Intramedullary spinal cord metastases: an increasingly common diagnosis
Payer S, Mende C, Westphal M, Eicker S
NEUROSURG FOCUS. 2015;39(2):E15.

Intramedullary spinal cavernoma: clinical presentation, microsurgical approach, and long-term outcome in a cohort of 48 patients
Reitz M, Burkhardt T, Vettorazzi E, Raimund F, Fritzsche E, Schmidt N, Regelsberger J, Westphal M, Eicker S
NEUROSURG FOCUS. 2015;39(2):E19.

Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups
Weller M, Weber R, Willscher E, Riehmer V, Hentschel B, Kreuz M, Felsberg J, Beyer U, Löffler-Wirth H, Kaulich K, Steinbach J, Hartmann C, Gramatzki D, Schramm J, Westphal M, Schackert G, Simon M, Martens T, Boström J, Hagel C, Sabel M, Krex D, Tonn J, Wick W, Noell S, Schlegel U, Radlwimmer B, Pietsch T, Loeffler M, von Deimling A, Binder H, Reifenberger G
ACTA NEUROPATHOL. 2015;129(5):679-693.

Pineal lesions: a multidisciplinary challenge
Westphal M, Emami P
Adv Tech Stand Neurosurg. 2015;42:79-102.

Circulating biomarkers for gliomas.
Westphal M, Lamszus K
NAT REV NEUROL. 2015;11(10):556-66.

Interferon-β Modulates the Innate Immune Response against Glioblastoma Initiating Cells
Wolpert F, Happold C, Reifenberger G, Florea A, Deenen R, Roth P, Neidert M, Lamszus K, Westphal M, Weller M, Eisele G
PLOS ONE. 2015;10(10):e0139603.

Identification of HERC5 and its potential role in NSCLC progression
Wrage M, Hagmann W, Kemming D, Uzunoglu F, Riethdorf S, Harms-Effenberger K, Westphal M, Lamszus K, Kim S, Becker N, Izbicki J, Sandoval J, Esteller M, Pantel K, Risch A, Wikman-Kocher H
INT J CANCER. 2015;136(10):2264-72.

Ocular ultrasound as an easy applicable tool for detection of Terson's syndrome after aneurysmal subarachnoid hemorrhage
Czorlich P, Burkhardt T, Knospe V, Richard G, Vettorazzi E, Wagenfeld L, Westphal M, Regelsberger J, Skevas C
PLOS ONE. 2014;9(12):e114907.

Terson syndrome in subarachnoid hemorrhage, intracerebral hemorrhage, and traumatic brain injury
Czorlich P, Skevas C, Knospe V, Vettorazzi E, Richard G, Wagenfeld L, Westphal M, Regelsberger J
NEUROSURG REV. 2014;38(1):129-136.

Tiefe Hirnstimulation: Neurophysiologische Therapie bei M. Parkinson und anderen neurologischen Erkrankungen. Ablauf und Ergebnisse
Goerendt I, Moll C, Fickel U, Gerloff C, Gulberti A, Hidding U, Köppen J, Pötter-Nerger M, Engel A, Westphal M, Buhmann C, Hamel W
Hamb Ärztebl. 2014;68(01):12-17.

High-frequency stimulation of the subthalamic nucleus counteracts cortical expression of major histocompatibility complex genes in a rat model of Parkinson's disease
Grieb B, Engler G, Sharott A, von Nicolai C, Streichert T, Papageorgiou I, Schulte A, Westphal M, Lamszus K, Engel A, Moll C, Hamel W
PLOS ONE. 2014;9(3):e91663.

Subthalamic deep brain stimulation improves auditory sensory gating deficit in Parkinson's disease
Gulberti A, Hamel W, Buhmann C, Boelmans K, Zittel-Dirks S, Gerloff C, Westphal M, Engel A, Schneider T, Moll C
CLIN NEUROPHYSIOL. 2014;126(3):565-574.

Angiolipoma of the sellar region
Hagel C, Goebell E, Westphal M, Saeger W
PITUITARY. 2014;18(1):176-178.

Anterior nucleus of the thalamus (ANT) stimulation in epilepsy: Stereotactic targeting and localisation of effective contacts
Köppen J, Voges B, Hause P, Nahravani F, Huckhagel T, Engel A, Westphal M, Stodieck S, Kuhlmann C, Gulberti A, Moll C, Hamel W
2014. XXIst Congress of the European Society for Stereotactic and Functional Neurosurgery. Temel Y, Krauss J, Nuttin B, Régis J, Sakas D, Schuurman R (eds.). S. Karger, 1-262.

Neuropsychological assessments in patients with aneurysmal subarachnoid hemorrhage, perimesencephalic SAH, and incidental aneurysms
Krajewski K, Dombek S, Martens T, Köppen J, Westphal M, Regelsberger J
NEUROSURG REV. 2014;37(1):55-62.

Long-term follow-up and quality of life in patients with intracranial germinoma
Martens T, Rotermund R, Zu Eulenburg C, Westphal M, Flitsch J
NEUROSURG REV. 2014;37(3):445-451.

Asymmetric pallidal neuronal activity in patients with cervical dystonia
Moll C, Galindo-Leon E, Sharott A, Gulberti A, Buhmann C, Koeppen J, Biermann M, Bäumer T, Zittel S, Westphal M, Gerloff C, Hamel W, Münchau A, Engel A
Front Syst Neurosci. 2014;8:15.

Hematogenous dissemination of glioblastoma multiforme
Müller C, Holtschmidt J, Auer M, Heitzer E, Lamszus K, Schulte A, Matschke J, Langer-Freitag S, Gasch C, Stoupiec M, Mauermann O, Peine S, Glatzel M, Speicher M, Geigl J, Westphal M, Pantel K, Riethdorf S
SCI TRANSL MED. 2014;6(247):247ra101.

Molecular characterization of long-term survivors of glioblastoma using genome- and transcriptome-wide profiling
Reifenberger G, Weber R, Riehmer V, Kaulich K, Willscher E, Wirth H, Gietzelt J, Hentschel B, Westphal M, Simon M, Schackert G, Schramm J, Matschke J, Sabel M, Gramatzki D, Felsberg J, Hartmann C, Steinbach J, Schlegel U, Wick W, Radlwimmer B, Pietsch T, Tonn J, von Deimling A, Binder H, Weller M, Loeffler M
INT J CANCER. 2014;135(8):1822-31.

Activity parameters of subthalamic nucleus neurons selectively predict motor symptom severity in Parkinson's disease
Sharott A, Gulberti A, Zittel-Dirks S, Tudor Jones A, Fickel U, Münchau A, Köppen J, Gerloff C, Westphal M, Buhmann C, Hamel W, Engel A, Moll C
J NEUROSCI. 2014;34(18):6273-6285.

Terson's Syndrome-Rate and Surgical Approach in Patients with Subarachnoid Hemorrhage: A Prospective Interdisciplinary Study
Skevas C, Czorlich P, Knospe V, Stemplewitz B, Richard G, Westphal M, Regelsberger J, Wagenfeld L
OPHTHALMOLOGY. 2014;121(8):1628-1633.

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients
Wikman-Kocher H, Westphal L, Schmid F, Pollari S, Kropidlowski J, Sielaff-Frimpong B, Glatzel M, Matschke J, Westphal M, Iljin K, Huhtala H, Terracciano L, Kallioniemi A, Sauter G, Müller V, Witzel I, Lamszus K, Kemming D, Pantel K
ONCOTARGET. 2014;5(10):3076-3087.

Inhibition of intracerebral glioblastoma growth by targeting the insulin-like growth factor 1 receptor involves different context-dependent mechanisms
Zamykal M, Martens T, Matschke J, Günther H, Kathagen A, Schulte A, Peters R, Westphal M, Lamszus K
NEURO-ONCOLOGY. 2014.

Incomplete tumour control following DNA vaccination against rat gliomas expressing a model antigen.
Ginzkey C, Eicker S, Marget M, Krause J, Brecht S, Westphal M, Hugo H, Mehdorn M, Steinmann J, Hamel W
ACTA NEUROCHIR. 2013;155(1):51-59.

MGMT promoter methylation status and prognosis of patients with primary or recurrent glioblastoma treated with carmustine wafers
Gutenberg A, Bock H, Brück W, Doerner L, Mehdorn H, Roggendorf W, Westphal M, Felsberg J, Reifenberger G, Giese A
BRIT J NEUROSURG. 2013;27(6):772-8.

The combination of carmustine wafers and temozolomide for the treatment of malignant gliomas. A comprehensive review of the rationale and clinical experience
Gutenberg A, Lumenta C, Braunsdorf W, Sabel M, Mehdorn H, Westphal M, Giese A
J NEURO-ONCOL. 2013;113(2):163-74.

Long-term survival in primary glioblastoma with versus without isocitrate dehydrogenase mutations
Hartmann C, Hentschel B, Simon M, Westphal M, Schackert G, Tonn J, Loeffler M, Reifenberger G, Pietsch T, von Deimling A, Weller M
CLIN CANCER RES. 2013;19(18):5146-57.

End-of-life caregivers' perception of medical and psychological support during the final weeks of glioma patients: a questionnaire-based survey
Heese O, Vogeler E, Martens T, Schnell O, Tonn J, Simon M, Schramm J, Krex D, Schackert G, Reithmeier T, Nikkhah G, Sabel M, Steiger H, Schlegel U, Löffler M, Weller M, Westphal M
NEURO-ONCOLOGY. 2013;15(9):1251-6.

Frequent genetic alterations in EGFR- and HER2-driven pathways in breast cancer brain metastases
Hohensee I, Lamszus K, Riethdorf S, Meyer-Staeckling S, Glatzel M, Matschke J, Witzel I, Westphal M, Brandt B, Müller V, Pantel K, Wikman H
AM J PATHOL. 2013;183(1):83-95.

Hypoxia and oxygenation induce a metabolic switch between pentose phosphate pathway and glycolysis in glioma stem-like cells
Kathagen A, Schulte A, Balcke G, Phillips H, Martens T, Matschke J, Günther H, Soriano R, Modrusan Z, Sandmann T, Kuhl C, Tissier A, Holz M, Krawinkel L, Glatzel M, Westphal M, Lamszus K
ACTA NEUROPATHOL. 2013;126(5):763-80.

Gross total but not incomplete resection of glioblastoma prolongs survival in the era of radiochemotherapy
Kreth F, Thon N, Simon M, Westphal M, Schackert G, Nikkhah G, Hentschel B, Reifenberger G, Pietsch T, Weller M, Tonn J
ANN ONCOL. 2013;24(12):3117-23.

Skeletal spread of an anaplastic astrocytoma (WHO grade III) and preservation of histopathological properties within metastases.
Martens T, Matschke J, Müller C, Riethdorf S, Balabanov S, Westphal M, Heese O
CLIN NEUROL NEUROSUR. 2013;115(3):323-328.

STN stimulation in general anaesthesia: evidence beyond 'evidence-based medicine'
Moll C, Payer S, Gulberti A, Sharott A, Zittel-Dirks S, Boelmans K, Köppen J, Gerloff C, Westphal M, Engel A, Oehlwein C, Buhmann C, Hamel W
ACTA NEUROCHIR SUPPL. 2013;117:19-25.

Growth behavior of plexiform neurofibromas after surgery
Nguyen R, Ibrahim C, Friedrich R, Westphal M, Schuhmann M, Mautner V
GENET MED. 2013;15(9):691-7.

Erlotinib resistance in EGFR-amplified glioblastoma cells is associated with upregulation of EGFRvIII and PI3Kp110δ
Schulte A, Liffers K, Kathagen A, Riethdorf S, Zapf S, Merlo A, Kolbe K, Westphal M, Lamszus K
NEURO-ONCOLOGY. 2013;15(10):1289-301.

Adenovirus-mediated gene therapy with sitimagene ceradenovec followed by intravenous ganciclovir for patients with operable high-grade glioma (ASPECT): a randomised, open-label, phase 3 trial
Westphal M, Ylä-Herttuala S, Martin J, Warnke P, Menei P, Eckland D, Kinley J, Kay R, Ram Z
LANCET ONCOL. 2013;14(9):823-33.

Prognostic or predictive value of MGMT promoter methylation in gliomas depends on IDH1 mutation
Wick W, Meisner C, Hentschel B, Platten M, Schilling A, Wiestler B, Sabel M, Koeppen S, Ketter R, Weiler M, Tabatabai G, von Deimling A, Gramatzki D, Westphal M, Schackert G, Loeffler M, Simon M, Reifenberger G, Weller M
NEUROLOGY. 2013;81(17):1515-22.

Nimotuzumab treatment of malignant gliomas.
Bode U, Massimino M, Bach F, Zimmermann M, Khuhlaeva E, Westphal M, Fleischhack G
EXPERT OPIN BIOL TH. 2012;12(12):1649-1659.

Case report: surviving a tiger attack.
Emami P, Kaiser T, Regelsberger J, Goebell E, Fiehler J, Westphal M, Heese O
NEUROSURG REV. 2012;35(4):621-624.

Patient satisfaction after anterior cervical discectomy and fusion is primarily driven by relieving pain.
Hessler C, Boysen K, Regelsberger J, Vettorazzi E, Winkler D, Westphal M
CLIN J PAIN. 2012;28(5):398-403.

Tödliche Armbrustverletzung im Jugendalter
Hessler C, Hamel W, Kluge S, Mayer U, Grzyska U, Westphal M, Püschel K
Arch Kriminol. 2012;229(3-4):90-95.

A hematogenous spread brain abscess invading the right damaged temporomandibular joint
Klatt J, Heiland M, Gröbe A, Westphal M, Schmelzle R, Pohlenz P
J CRANIO MAXILL SURG. 2012;40(8):e307-9.

Predictive impact of MGMT promoter methylation in glioblastoma of the elderly.
Reifenberger G, Hentschel B, Felsberg J, Schackert G, Simon M, Schnell O, Westphal M, Wick W, Pietsch T, Loeffler M, Weller M, Network G
INT J CANCER. 2012;131(6):1342-1350.

Intranasal delivery of neural stem/progenitor cells: a noninvasive passage to target intracerebral glioma.
Reitz M, Demestre M, Sedlacik J, Meissner H, Fiehler J, Kim S, Westphal M, Schmidt N
STEM CELL TRANSL MED. 2012;1(12):866-873.

Glioblastoma stem-like cell lines with either maintenance or loss of high-level EGFR amplification, generated via modulation of ligand concentration.
Schulte A, Günther H, Martens T, Zapf S, Riethdorf S, Wülfing C, Stoupiec M, Westphal M, Lamszus K
CLIN CANCER RES. 2012;18(7):1901-1913.

NovoTTF-100A versus physician's choice chemotherapy in recurrent glioblastoma: a randomised phase III trial of a novel treatment modality.
Stupp R, Wong E, Kanner A, Steinberg D, Engelhard H, Heidecke V, Kirson E, Taillibert S, Liebermann F, Dbalý V, Ram Z, Villano J, Rainov N, Weinberg U, Schiff D, Kunschner L, Raizer J, Honnorat J, Sloan A, Malkin M, Landolfi J, Payer F, Mehdorn M, Weil R, Pannullo S, Westphal M, Smrcka M, Chin L, Kostron H, Hofer S, Bruce J, Cosgrove R, Paleologous N, Palti Y, Gutin P
EUR J CANCER. 2012;48(14):2192-2202.

Relevance of PTEN loss in brain metastasis formation in breast cancer patients.
Wikman H, Lamszus K, Detels N, Uslar L, Wrage M, Benner C, Hohensee I, Ylstra B, Eylmann K, Zapatka M, Sauter G, Kemming D, Glatzel M, Müller V, Westphal M, Pantel K
BREAST CANCER RES. 2012;14(2):49.

Clinical relevance of loss of 11p15 in primary and metastatic breast cancer: association with loss of PRKCDBP expression in brain metastases.
Wikman H, Sielaff-Frimpong B, Kropidlowski J, Witzel I, Milde-Langosch K, Sauter G, Westphal M, Lamszus K, Pantel K
PLOS ONE. 2012;7(10):47537.

Glioblastoma in childhood – Treatment and outcome of 7 patients
Burkhardt T, Emami P, Kordes U, Matschke J, Regelsberger J, Westphal M, Kammler G
2011. 62. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC) Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgen (PNCH). .

Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas.
Felsberg J, Thon N, Eigenbrod S, Hentschel B, Sabel M, Westphal M, Schackert G, Kreth F, Pietsch T, Löffler M, Weller M, Reifenberger G, Tonn J, Network G
INT J CANCER. 2011;129(3):659-670.

Deep brain stimulation of the subthalamic nucleus normalises Parkinson‘s disease related abnormalities of auditory evoked potentials and quantitative EEG
Gulberti A, Moll C, Schneider T, Hamel W, Muenchau A, Buhmann C, Boelmans K, Zittel S, Gerloff C, Westphal M, Engel A
2011. 62nd Annual Meeting of the German Society of Neurosurgery (DGNC). .

A survey on clinical study participation and study infrastructure at non-university hospitals in Germany.
Heese O, Böger R, Westphal M
INT J CLIN PHARM TH. 2011;49(9):531-535.

[Functional and radiological outcome after ACDF in 67 cases].
Hessler C, Boysen K, Westphal M, Regelsberger J
Z ORTHOP UNFALLCHIR. 2011;149(6):683-687.

Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.
Lai A, Kharbanda S, Pope W, Tran A, Solis O, Peale F, Forrest W, Pujara K, Carrillo J, Pandita A, Ellingson B, Bowers C, Soriano R, Schmidt N, Mohan S, Yong W, Seshagiri S, Modrusan Z, Jiang Z, Aldape K, Mischel P, Liau L, Escovedo C, Chen W, Nghiemphu P, James C, Prados M, Westphal M, Lamszus K, Cloughesy T, Phillips H
J CLIN ONCOL. 2011;29(34):4482-4490.

Consensus document on European brain research.
Monica D, Baker M, Corradetti R, Kettenmann H, Mendlewicz J, Olesen J, Ragan I, Westphal M
EUR J NEUROSCI. 2011;33(5):768-818.

Effect of imaging and catheter characteristics on clinical outcome for patients in the PRECISE study.
Mueller S, Polley M, Lee B, Kunwar S, Pedain C, Wembacher-Schröder E, Mittermeyer S, Westphal M, Sampson J, Vogelbaum M, Croteau D, Chang S
J NEURO-ONCOL. 2011;101(2):267-277.

Non-Conventional Treatments Sought by Patients after Surgery for Intramedullary Spinal Cord Tumors.
Raimund F, Nickel S, Hessler C, Regelsberger J, Westphal M, Heese O
ZBL NEUROCHIR. 2011;72(2):71-74.

Training Microneurosurgery - Four Years Experiences with an in vivo Model.
Regelsberger J, Heese O, Horn P, Kirsch M, Eicker S, Sabel M, Westphal M
ZBL NEUROCHIR. 2011;72(4):192-195.

Blister-like aneurysms--a diagnostic and therapeutic challenge.
Regelsberger J, Matschke J, Grzyska U, Ries T, Fiehler J, Köppen J, Westphal M
NEUROSURG REV. 2011;34(4):409-416.

How to deal with incompletely treated AVMs: experience of 67 cases and review of the literature.
Reitz M, Schmidt N, Vukovic Z, Grzyska U, Zeumer H, Westphal M, Regelsberger J
ACTA NEUROCHIR SUPPL. 2011;112:123-129.

56-year old woman with sphenoid wing tumor.
Reitz M, Zustin J, Matschke J, Schmidt N, Westphal M
BRAIN PATHOL. 2011;21(2):225-228.

Signal intensity in T2' magnetic resonance imaging is related to brain glioma grade.
Saitta L, Heese O, Förster A, Matschke J, Siemonsen S, Castellan L, Westphal M, Fiehler J, Goebell E
EUR RADIOL. 2011;21(5):1068-1076.

Congenital cervical tethered cord in an adult: utility of spinal diffusion tensor MR imaging.
Schmidt N, Raimund F, Förster A, Matschke J, Regelsberger J, Fiehler J, Winkler D, Westphal M
ZBL NEUROCHIR. 2011;72(4):208-210.

Clinical relevance of associated aneurysms with arteriovenous malformations of the posterior fossa.
Schmidt N, Reitz M, Raimund F, Treszl A, Grzyska U, Westphal M, Regelsberger J
ACTA NEUROCHIR SUPPL. 2011;112:131-135.

A distinct subset of glioma cell lines with stem cell-like properties reflects the transcriptional phenotype of glioblastomas and overexpresses CXCR4 as therapeutic target.
Schulte A, Günther H, Phillips H, Kemming D, Martens T, Kharbanda S, Soriano R, Modrusan Z, Zapf S, Westphal M, Lamszus K
GLIA. 2011;59(4):590-602.

Cytoreductive surgery of glioblastoma as the key to successful adjuvant therapies: new arguments in an old discussion.
Stummer W, Bent v, Westphal M, Westphal M
ACTA NEUROCHIR. 2011;153(6):1211-1218.

The neurobiology of gliomas: from cell biology to the development of therapeutic approaches
Westphal M, Lamszus K
NAT REV NEUROSCI. 2011;12(9):495-508.

Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma.

NEURO-ONCOLOGY. 2010;12(8):871-881.

Proton beam therapy for loco-regional control of a recurrent mixed malignant germ cell tumor of the skull in a 22-month-old girl.
Calaminus G, Göbel U, Schrum J, Wittkugel O, Westphal M, Timmermann B
KLIN PADIATR. 2010;222(3):175-179.

A hierarchy of self-renewing tumor-initiating cell types in glioblastoma.
Chen R, Nishimura M, Bumbaca S, Kharbanda S, Forrest W, Kasman I, Greve J, Soriano R, Gilmour L, Rivers C, Modrusan Z, Nacu S, Guerrero S, Edgar K, Wallin J, Lamszus K, Westphal M, Heim S, James C, VandenBerg S, Costello J, Moorefield S, Cowdrey C, Prados M, Phillips H
CANCER CELL. 2010;17(4):362-375.

Increase in tumor size following intratumoral injection of immunostimulatory CpG-containing oligonucleotides in a rat glioma model.
Ginzkey C, Eicker S, Marget M, Krause J, Brecht S, Westphal M, Hugo H, Mehdorn H, Steinmann J, Hamel W
CANCER IMMUNOL IMMUN. 2010;59(4):541-551.

Impact of subthalamic deep brain stimulation on auditory information processing in patients with advanced Parkinson ́s disease
Gulberti A, Moll C, Schneider T, Hamel W, Muenchau A, Boelmans K, Zittel S, Gerloff C, Westphal M, Engel A
2010. IBAGS X. .

A 3-dimensional extracellular matrix as a delivery system for the transplantation of glioma-targeting neural stem/progenitor cells.
Hansen K, Müller F, Messing M, Zeigler F, Loring J, Lamszus K, Westphal M, Schmidt N
NEURO-ONCOLOGY. 2010;12(7):645-654.

Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas.
Hartmann C, Hentschel B, Wick W, Capper D, Felsberg J, Simon M, Westphal M, Schackert G, Meyermann R, Pietsch T, Reifenberger G, Weller M, Loeffler M, von Deimling A
ACTA NEUROPATHOL. 2010;120(6):707-718.

Complementary therapy use in patients with glioma: an observational study.
Heese O, Schmidt M, Nickel S, Berger H, Goldbrunner R, Tonn J, Bhär O, Steinbach J, Simon M, Schramm J, Krex D, Schackert G, Reithmeier T, Nikkhah G, Löffler M, Weller M, Westphal M
NEUROLOGY. 2010;75(24):2229-2235.

Tragödie an Silvester - Feuerwerksunfälle
Hessler C, Martens T, Westphal M, Püschel K, Stute J, Anders S
Hamb Ärztebl. 2010;64(2):32-33.

Inhibition of thromboxane synthase activity improves glioblastoma response to alkylation chemotherapy.
Schmidt N, Ziu M, Cargioli T, Westphal M, Giese A, Black P, Carroll R
TRANSL ONCOL. 2010;3(1):43-49.

Giant cell glioblastoma is associated with altered aurora b expression and concomitant p53 mutation.
Temme A, Geiger K, Wiedemuth R, Conseur K, Pietsch T, Felsberg J, Reifenberger G, Tatsuka M, Hagel C, Westphal M, Berger H, Simon M, Weller M, Schackert G
J NEUROPATH EXP NEUR. 2010;69(6):632-642.

[Local therapy of primary brain tumors].
Westphal M, Stummer W
NERVENARZT. 2010;81(8):913-914, 916-917.

RON receptor tyrosine kinase in human gliomas: expression, function, and identification of a novel soluble splice variant.
Eckerich C, Schulte A, Martens T, Zapf S, Westphal M, Lamszus K
J NEUROCHEM. 2009;109(4):969-980.

Therapeutic clues in spinal dural arteriovenous fistulas - a 30 year experience of 156 cases.
Hessler C, Regelsberger J, Grzyska U, Illies T, Zeumer H, Westphal M
ZBL NEUROCHIR. 2009.

Waking up the brain: a case study of stimulation-induced wakeful unawareness during anaesthesia.
Moll C, Sharott A, Hamel W, Münchau A, Buhmann C, Hidding U, Zittel S, Westphal M, Müller D, Engel A
PROG BRAIN RES. 2009;177:125-145.

Lumbar spinal stenosis: prognostic factors for bilateral microsurgical decompression using a unilateral approach.
Papavero L, Thiel M, Fritzsche E, Kunze C, Westphal M, Kothe R
NEUROSURGERY. 2009;65(6):182-187.

Intracranial aneurysms in childhood: report of 8 cases and review of the literature.
Regelsberger J, Heese O, Martens T, Ries T, Kunkel P, Westphal M
ZBL NEUROCHIR. 2009;70(2):79-85.

Poor drug distribution as a possible explanation for the results of the PRECISE trial.
Sampson J, Archer G, Pedain C, Wembacher-Schröder E, Westphal M, Kunwar S, Vogelbaum M, Coan A, Herndon J, Raghu R, Brady M, Reardon D, Friedman A, Friedman H, Rodríguez-Ponce M, Chang S, Mittermeyer S, Croteau D, Puri R
J NEUROSURG. 2009.

Vascular endothelial growth factor-stimulated cerebral microvascular endothelial cells mediate the recruitment of neural stem cells to the neurovascular niche.
Schmidt N, Koeder D, Messing M, Mueller F, Aboody K, Kim S, Black P, Carroll R, Westphal M, Lamszus K
BRAIN RES. 2009;1268:24-37.

Entrainment of STN neurons by cortical beta oscillations in Parkinson's disease
Sharott A, Gulberti A, Hamel W, Köppen J, Zittel S, Hidding U, Gerloff C, Westphal M, Engel A, Moll C
2009. 2009 Neuroscience Meeting Planner. .

Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network.
Weller M, Felsberg J, Hartmann C, Berger H, Steinbach J, Schramm J, Westphal M, Schackert G, Simon M, Tonn J, Heese O, Krex D, Nikkhah G, Pietsch T, Wiestler O, Reifenberger G, von Deimling A, Loeffler M
J CLIN ONCOL. 2009;27(34):5743-5750.

Other experimental therapies for glioma.
Westphal M, Lamszus K
Recent Results Cancer Res. 2009;171:155-164.

Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria.
Günther H, Schmidt N, Phillips H, Kemming D, Kharbanda S, Soriano R, Modrusan Z, Meissner H, Westphal M, Lamszus K
ONCOGENE. 2008;27(20):2897-2909.

Inhibition of glioblastoma growth in a highly invasive nude mouse model can be achieved by targeting epidermal growth factor receptor but not vascular endothelial growth factor receptor-2.
Martens T, Laabs Y, Günther H, Kemming D, Zhu Z, Witte L, Hagel C, Westphal M, Lamszus K
CLIN CANCER RES. 2008;14(17):5447-5458.

The translaminar approach to lumbar disc herniations impinging the exiting root.
Papavero L, Langer N, Fritzsche E, Emami P, Westphal M, Kothe R
NEUROSURGERY. 2008;62(3 Suppl 1):173-178.

Gene expression profiling of hypothalamic hamartomas: a search for genes associated with central precocious puberty.
Parent A, Matagne V, Westphal M, Heger S, Ojeda S, Jung H
HORM RES. 2008;69(2):114-123.

Secretory meningiomas: a benign subgroup causing life-threatening complications.
Regelsberger J, Hagel C, Emami P, Ries T, Heese O, Westphal M
NEURO-ONCOLOGY. 2008.

Hypoxia can induce c-Met expression in glioma cells and enhance SF/HGF-induced cell migration.
Eckerich C, Zapf S, Fillbrandt R, Loges S, Westphal M, Lamszus K
INT J CANCER. 2007;121(2):276-283.

Pallidal neuronal activity in myoclonus-dystonia syndrome
Gulberti A, Moll C, Sharott A, Hamel W, Muenchau A, Buhmann C, Hidding U, Zittel S, Gerloff C, Westphal M, Müller D, Engel A
2007. IBAGS IX. .

Autophagic cell death induced by TrkA receptor activation in human glioblastoma cells.
Hansen K, Wagner B, Hamel W, Schweizer M, Haag F, Westphal M, Lamszus K
J NEUROCHEM. 2007;103(1):259-275.

arousal reaction due to electrical stimulation of the globus pallidus
Moll C, Sharrott A, Buhmann C, Hidding U, Zittel S, Westphal M, Hamel W, Engel A
ACTA PHYSIOL. 2007;189.

The impact of esophagus retraction on early dysphagia after anterior cervical surgery: does a correlation exist?
Papavero L, Heese O, Klotz-Regener V, Buchalla R, Schröder F, Westphal M
SPINE. 2007;32(10):1089-1093.

Combined 1p/19q loss in oligodendroglial tumors: predictive or prognostic biomarker?
Weller M, Berger H, Hartmann C, Schramm J, Westphal M, Simon M, Goldbrunner R, Krex D, Steinbach J, Ostertag C, Loeffler M, Pietsch T, von Deimling A
CLIN CANCER RES. 2007;13(23):6933-6937.

Contactin is expressed in human astrocytic gliomas and mediates repulsive effects.
Eckerich C, Zapf S, Ulbricht U, Müller S, Fillbrandt R, Westphal M, Lamszus K
GLIA. 2006;53(1):1-12.

Terlipressin for haemodynamic support in septic shock: less may be more.
Ertmer C, Bone H, Hugo V, Westphal M
RESUSCITATION. 2006;70(2):292-293.

Diagnosis and treatment of an intramedullary cavernoma in a young male with an implanted cardiac pacemaker.
Fritzsche E, Flitsch J, Kucinski T, Lund G, Papavero L, Westphal M
ACTA NEUROCHIR. 2006;148(11):1213-1215.

Disarrangement of fiber tracts and decline of neuronal density correlate in glioma patients--a combined diffusion tensor imaging and 1H-MR spectroscopy study.
Goebell E, Fiehler J, Ding X, Paustenbach S, Nietz S, Heese O, Kucinski T, Hagel C, Westphal M, Zeumer H
AM J NEURORADIOL. 2006;27(7):1426-1431.

Low-grade and anaplastic gliomas: differences in architecture evaluated with diffusion-tensor MR imaging.
Goebell E, Paustenbach S, Vaeterlein O, Ding X, Heese O, Fiehler J, Kucinski T, Hagel C, Westphal M, Zeumer H
RADIOLOGY. 2006;239(1):217-222.

Intraoperative measurement of pharynx/esophagus retraction during anterior cervical surgery. Part II: perfusion.
Heese O, Fritzsche E, Heiland M, Westphal M, Papavero L
EUR SPINE J. 2006;15(12):1839-1843.

Intraoperative measurement of pharynx/esophagus retraction during anterior cervical surgery. Part I: pressure.
Heese O, Schröder F, Westphal M, Papavero L
EUR SPINE J. 2006;15(12):1833-1837.

Outcome prediction of third ventriculostomy: a proposed hydrocephalus grading system.
Kehler U, Regelsberger J, Gliemroth J, Westphal M
MINIM INVAS NEUROSUR. 2006;49(4):238-243.

A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo.
Martens T, Schmidt N, Eckerich C, Fillbrandt R, Merchant M, Schwall R, Westphal M, Lamszus K
CLIN CANCER RES. 2006;12(20 Pt 1):6144-6152.

Consensus document on European brain research.
Olesen J, Baker M, Freund T, Monica D, Mendlewicz J, Ragan I, Westphal M
J NEUROL NEUROSUR PS. 2006;77(1):1-49.

Ultrasound in the diagnosis of craniosynostosis.
Regelsberger J, Delling G, Helmke K, Tsokos M, Kammler G, Kränzlein H, Westphal M
J CRANIOFAC SURG. 2006;17(4):623-628.

High-frequency ultrasound confirmation of positional plagiocephaly.
Regelsberger J, Delling G, Tsokos M, Helmke K, Kammler G, Kränzlein H, Westphal M
J NEUROSURG. 2006;105(5):413-417.

RNA interference targeting protein tyrosine phosphatase zeta/receptor-type protein tyrosine phosphatase beta suppresses glioblastoma growth in vitro and in vivo.
Ulbricht U, Eckerich C, Fillbrandt R, Westphal M, Lamszus K
J NEUROCHEM. 2006;98(5):1497-1506.

Gliadel wafer in initial surgery for malignant glioma: long-term follow-up of a multicenter controlled trial.
Westphal M, Ram Z, Riddle V, Hilt D, Bortey E
ACTA NEUROCHIR. 2006;148(3):269-275.

Well-differentiated neurocytoma: what is the best available treatment?
Rades D, Fehlauer F, Lamszus K, Schild S, Hagel C, Westphal M, Alberti W
NEURO-ONCOLOGY. 2005;7(1):77-83.

Cyclo-oxygenase inhibitors and thromboxane synthase inhibitors differentially regulate migration arrest, growth inhibition and apoptosis in human glioma cells
Kürzel F, Hagel C, Zapf S, Meissner H, Westphal M, Giese A
ACTA NEUROCHIR. 2002;144(1):71-87.

Thromboxane synthase regulates the migratory phenotype of human glioma cells
Giese A, Hagel C, Kim E, Zapf S, Djawaheri J, Berens M, Westphal M
NEURO-ONCOLOGY. 1999;1(1):3-13.

Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angiogenesis
Schmidt N, Westphal M, Hagel C, Ergün S, Stavrou D, Rosen E, Lamszus K
INT J CANCER. 1999;84(1):10-18.

Trk A, B, and C are commonly expressed in human astrocytes and astrocytic gliomas but not by human oligodendrocytes and oligodendroglioma
Wang Y, Hagel C, Hamel W, Müller S, Kluwe L, Westphal M
ACTA NEUROPATHOL. 1998;96(4):357-64.

Primary spinal malignant schwannoma: clinical, histological and cytogenetic findings
Valdueza J, Hagel C, Westphal M, Hänsel M, Herrmann H
NEUROSURG REV. 1991;14(4):283-91.

Letzte Aktualisierung aus dem FIS: 21.11.2024 - 03:53 Uhr