2024

Identification and development of TRPM4 antagonists to counteract neuronal excitotoxicity
Binkle-Ladisch L, Pironet A, Zaliani A, Alcouffe C, Mensching D, Haferkamp U, Willing A, Woo M, Erdmann A, Jessen T, Hess S, Gribbon P, Pless O, Vennekens R, Friese M
ISCIENCE. 2024;27(12):111425.

Fluid excess on intensive care unit after mechanical thrombectomy after acute ischemic stroke is associated with unfavorable neurological and functional outcomes: An observational cohort study
Schell M, Mayer C, Woo M, Leischner H, Fischer M, Grensemann J, Kluge S, Czorlich P, Gerloff C, Fiehler J, Thomalla G, Flottmann F, Schweingruber N
EUR STROKE J. 2024 [Epub ahead of print];23969873241271642.

Early prediction of ventricular peritoneal shunt dependency in aneurysmal subarachnoid haemorrhage patients by recurrent neural network-based machine learning using routine intensive care unit data
Schweingruber N, Bremer J, Wiehe A, Mader M, Mayer C, Woo M, Kluge S, Grensemann J, Quandt F, Gempt J, Fischer M, Thomalla G, Gerloff C, Sauvigny J, Czorlich P
J CLIN MONIT COMPUT. 2024;38(5):1175-1186.

Diagnosis of Alzheimer's disease using plasma biomarkers adjusted to clinical probability
Therriault J, Janelidze S, Benedet A, Ashton N, Arranz Martínez J, Gonzalez-Escalante A, Bellaver B, Alcolea D, Vrillon A, Karim H, Mielke M, Hyung Hong C, Roh H, Contador J, Puig Pijoan A, Algeciras-Schimnich A, Vemuri P, Graff-Radford J, Lowe V, Karikari T, Jonaitis E, Brum W, Tissot C, Servaes S, Rahmouni N, Macedo A, Stevenson J, Fernandez-Arias J, Wang Y, Woo M, Friese M, Jia W, Dumurgier J, Hourregue C, Cognat E, Ferreira P, Vitali P, Johnson S, Pascoal T, Gauthier S, Lleó A, Paquet C, Petersen R, Salmon D, Mattsson-Carlgren N, Palmqvist S, Stomrud E, Galasko D, Son S, Zetterberg H, Fortea J, Suárez-Calvet M, Jack C, Blennow K, Hansson O, Rosa-Neto P
NATURE AGING. 2024;4(11):1529-1537.

Comparison of immunoassay- with mass spectrometry-derived p-tau quantification for the detection of Alzheimer's disease pathology
Therriault J, Woo M, Salvadó G, Gobom J, Karikari T, Janelidze S, Servaes S, Rahmouni N, Tissot C, Ashton N, Benedet A, Montoliu-Gaya L, Macedo A, Lussier F, Stevenson J, Vitali P, Friese M, Massarweh G, Soucy J, Pascoal T, Stomrud E, Palmqvist S, Mattsson-Carlgren N, Gauthier S, Zetterberg H, Hansson O, Blennow K, Rosa-Neto P
MOL NEURODEGENER. 2024;19(1):2.

Protective effect of TCR-mediated MAIT cell activation during experimental autoimmune encephalomyelitis
Walkenhorst M, Sonner J, Meurs N, Engler J, Bauer S, Winschel I, Woo M, Raich L, Winkler I, Vieira V, Unger L, Salinas G, Lantz O, Friese M, Willing A
NAT COMMUN. 2024;15(1):9287.

The relation of synaptic biomarkers with Aβ, tau, glial activation, and neurodegeneration in Alzheimer's disease
Wang Y, Ashton N, Servaes S, Nilsson J, Woo M, Pascoal T, Tissot C, Rahmouni N, Therriault J, Lussier F, Chamoun M, Gauthier S, Brinkmalm A, Zetterberg H, Blennow K, Rosa-Neto P, Benedet A
TRANSL NEURODEGENER. 2024;13(1):27.

Sex- and species-specific contribution of CD99 to T cell costimulation during multiple sclerosis
Winschel I, Willing A, Engler J, Walkenhorst M, Meurs N, Binkle-Ladisch L, Woo M, Pfeffer L, Sonner J, Borgmeyer U, Hagen S, Grünhagel B, Claussen J, Altfeld M, Friese M
BIOL SEX DIFFER. 2024;15(1):41.

Astrocytic uptake of posttranslationally modified amyloid-β leads to endolysosomal system disruption and induction of pro-inflammatory signaling
Wirth S, Schlößer A, Beiersdorfer A, Schweizer M, Woo M, Friese M, Lohr C, Grochowska K
GLIA. 2024;72(8):1451-1468.

The NR4A2/VGF pathway fuels inflammation-induced neurodegeneration via promoting neuronal glycolysis
Woo M, Bal L, Winschel I, Manca E, Walkenhorst M, Sevgili B, Sonner J, Di Liberto G, Mayer C, Binkle-Ladisch L, Rothammer N, Unger L, Raich L, Hadjilaou A, Noli B, Manai A, Vieira V, Meurs N, Wagner I, Pless O, Cocco C, Stephens S, Glatzel M, Merkler D, Friese M
J CLIN INVEST. 2024;134(16):.

The neuropathobiology of multiple sclerosis
Woo M, Engler J, Friese M
NAT REV NEUROSCI. 2024;25(7):493-513.

STING orchestrates the neuronal inflammatory stress response in multiple sclerosis
Woo M, Mayer C, Binkle-Ladisch L, Sonner J, Rosenkranz S, Shaposhnykov A, Rothammer N, Tsvilovskyy V, Lorenz S, Raich L, Bal L, Vieira V, Wagner I, Bauer S, Glatzel M, Conrad M, Merkler D, Freichel M, Friese M
CELL. 2024;187(15):4043-4060.e30.

Identification of late-stage tau accumulation using plasma phospho-tau217
Woo M, Therriault J, Jonaitis E, Wilson R, Langhough R, Rahmouni N, Benedet A, Ashton N, Tissot C, Lantero-Rodriguez J, Macedo A, Servaes S, Wang Y, Arias J, Hosseini S, Betthauser T, Lussier F, Hopewell R, Triana-Baltzer G, Kolb H, Jeromin A, Kobayashi E, Massarweh G, Friese M, Klostranec J, Vilali P, Pascoal T, Gauthier S, Zetterberg H, Blennow K, Johnson S, Rosa-Neto P
EBIOMEDICINE. 2024;109:105413.

Plasma pTau-217 and N-terminal tau (NTA) enhance sensitivity to identify tau PET positivity in amyloid-β positive individuals
Woo M, Tissot C, Lantero-Rodriguez J, Snellman A, Therriault J, Rahmouni N, Macedo A, Servaes S, Wang Y, Arias J, Hosseini S, Chamoun M, Lussier F, Benedet A, Ashton N, Karikari T, Triana-Baltzer G, Kolb H, Stevenson J, Mayer C, Kobayashi E, Massarweh G, Friese M, Pascoal T, Gauthier S, Zetterberg H, Blennow K, Rosa-Neto P
ALZHEIMERS DEMENT. 2024;20(2):1166-1174.

2023

Comparative analysis of characteristics and outcomes in hospitalized COVID-19 patients infected with different SARS-CoV-2 variants between January 2020 and April 2022 - A retrospective single-center cohort study
Brehm T, Heyer A, Woo M, Fischer M, van der Meirschen M, Wichmann D, Jarczak D, Roedl K, Schmiedel S, Addo M, Lütgehetmann M, Christner M, Huber S, Lohse A, Kluge S, Schulze Zur Wiesch J
J INFECT PUBLIC HEAL. 2023;16(11):1806-1812.

Jacob-induced transcriptional inactivation of CREB promotes Aβ-induced synapse loss in Alzheimer's disease
Grochowska K, Gomes G, Raman R, Kaushik R, Sosulina L, Kaneko H, Oelschlegel A, Yuanxiang P, Reyes-Resina I, Bayraktar G, Samer S, Spilker C, Woo M, Morawski M, Goldschmidt J, Friese M, Rossner S, Navarro G, Remy S, Reissner C, Karpova A, Kreutz M
EMBO J. 2023;42(4):.

History of cerebrovascular disease but not dementia increases the risk for secondary vascular events during SARS-CoV-2 infection with presumed Omicron variant: a retrospective observational study
Mayer C, Woo M, Brehm T, Heyer A, Fischer M, Fischbach F, Bal L, Addo M, Kluge S, Thomalla G, Schweingruber N, Wiesch J
EUR J NEUROL. 2023;30(8):2297-2304.

Sotrovimab in Hospitalized Patients with SARS-CoV-2 Omicron Variant Infection: a Propensity Score-Matched Retrospective Cohort Study
Woo M, Brehm T, Fischer M, Heyer A, Wichmann D, Jordan S, Nörz D, Lütgehetmann M, Addo M, Lohse A, Schmiedel S, Kluge S, Schulze Zur Wiesch J
MICROBIOL SPECTR. 2023;11(1):.

Atraumatic spinal needle indicates correct CSF opening pressure
Woo M, Kessner S, Schlemm E, Gerloff C
SCI REP-UK. 2023;12(1):21089.

Absence of self-reported neuropsychiatric and somatic symptoms after Omicron variant SARS-CoV-2 breakthrough infections
Woo M, Mayer C, Brehm T, Andersen G, Weigel A, Löwe B, Lohse A, Addo M, Gerloff C, Knobloch J, Schulze Zur Wiesch J, Friese M
BRAIN COMMUN. 2023;5(2):fcad092.

Clinical surrogates of dysautonomia predict lethal outcome in COVID-19 on intensive care unit
Woo M, Mayer C, Fischer M, Kluge S, Roedl K, Gerloff C, Czorlich P, Thomalla G, Schulze Zur Wiesch J, Schweingruber N
NEUROL RES PRACT. 2023;5(1):17.

14-3-3 ζ/δ-reported early synaptic injury in Alzheimer’s disease is independently mediated by sTREM2
Woo M, Nilsson J, Therriault J, Rahmouni N, Brinkmalm A, Benedet A, Ashton N, Macedo A, Servaes S, Wang Y, Tissot C, Arias J, Hosseini S, Chamoun M, Lussier F, Karikari T, Stevenson J, Mayer C, Ferrari-Souza J, Kobayashi E, Massarweh G, Friese M, Pascoal T, Gauthier S, Zetterberg H, Blennow K, Rosa-Neto P
J NEUROINFLAMM. 2023;20(1):278.

Vagus nerve inflammation contributes to dysautonomia in COVID-19
Woo M, Shafiq M, Fitzek A, Dottermusch M, Altmeppen H, Mohammadi B, Mayer C, Bal L, Raich L, Matschke J, Krasemann S, Pfefferle S, Brehm T, Lütgehetmann M, Schädler J, Addo M, Schulze Zur Wiesch J, Ondruschka B, Friese M, Glatzel M
ACTA NEUROPATHOL. 2023;146(3):387-394.

Calcium channel β3 subunit regulates ATP-dependent migration of dendritic cells
Woo M, Ufer F, Sonner J, Belkacemi A, Tintelnot J, Sáez P, Krieg P, Mayer C, Binkle-Ladisch L, Engler J, Bauer S, Kursawe N, Vieira V, Mannebach S, Freichel M, Flockerzi V, Vargas P, Friese M
SCI ADV. 2023;9(38):.

2022

The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2
Krasemann S, Haferkamp U, Pfefferle S, Woo M, Heinrich F, Schweizer M, Appelt-Menzel A, Cubukova A, Barenberg J, Leu J, Hartmann K, Thies E, Littau J, Sepulveda-Falla D, Zhang L, Ton K, Liang Y, Matschke J, Ricklefs F, Sauvigny T, Sperhake J, Fitzek A, Gerhartl A, Brachner A, Geiger N, König E, Bodem J, Franzenburg S, Franke A, Moese S, Müller F, Geisslinger G, Claussen C, Kannt A, Zaliani A, Gribbon P, Ondruschka B, Neuhaus W, Friese M, Glatzel M, Pless O
STEM CELL REP. 2022;17(2):307-320.

G9a dictates neuronal vulnerability to inflammatory stress via transcriptional control of ferroptosis
Rothammer N, Woo M, Bauer S, Binkle-Ladisch L, Di Liberto G, Egervari K, Wagner I, Haferkamp U, Pless O, Merkler D, Engler J, Friese M
SCI ADV. 2022;8(31):.

2021

Multi-dimensional and longitudinal systems profiling reveals predictive pattern of severe COVID-19
Woo M, Haag F, Nierhaus A, Jarczak D, Roedl K, Mayer C, Brehm T, van der Meirschen M, Hennigs A, Christopeit M, Fiedler W, Karagiannis P, Burdelski C, Schultze A, Huber S, Addo M, Schmiedel S, Friese M, Kluge S, Schulze Zur Wiesch J
ISCIENCE. 2021;24(7):102752.

Control of SARS-CoV-2 infection in rituximab-treated neuroimmunological patients
Woo M, Steins D, Häußler V, Kohsar M, Haag F, Elias-Hamp B, Heesen C, Lütgehetmann M, Schulze Zur Wiesch J, Friese M
J NEUROL. 2021;268(1):5-7.

Neuronal metabotropic glutamate receptor 8 protects against neurodegeneration in CNS inflammation
Woo M, Ufer F, Rothammer N, Di Liberto G, Binkle L, Haferkamp U, Sonner J, Engler J, Hornig S, Bauer S, Wagner I, Egervari K, Raber J, Duvoisin R, Pless O, Merkler D, Friese M
J EXP MED. 2021;218(5):.

Activity-regulated cytoskeleton-associated protein/activity-regulated gene 3.1 (Arc/Arg3.1) enhances dendritic cell vaccination in experimental melanoma
Zhang X, Huck K, Jähne K, Cichon F, Sonner J, Ufer F, Bauer S, Woo M, Green E, Lu K, Kilian M, Friese M, Platten M, Sahm K
ONCOIMMUNOLOGY. 2021;10(1):1920739.

2020

Contribution of NAADP to Glutamate-Evoked Changes in Ca2+ Homeostasis in Mouse Hippocampal Neurons
Hermann J, Bender M, Schumacher D, Woo M, Shaposhnykov A, Rosenkranz S, Kuryshev V, Meier C, Guse A, Friese M, Freichel M, Tsvilovskyy V
FRONT CELL DEV BIOL. 2020;8:496.

Voltage-Gated Proton Channel Hv1 Controls TLR9 Activation in Plasmacytoid Dendritic Cells
Montes-Cobos E, Huscher B, Engler J, Woo M, Binkle L, Bauer S, Kursawe N, Moles M, Friese M, Ufer F
J IMMUNOL. 2020;205(11):3001-3010.

Frequent neurocognitive deficits after recovery from mild COVID-19
Woo M, Malsy J, Pöttgen J, Seddiq Zai S, Ufer F, Hadjilaou A, Schmiedel S, Addo M, Gerloff C, Heesen C, Schulze zur Wiesch J, Friese M
BRAIN COMMUN. 2020;2(2):fcaa205.

2019

Bassoon proteinopathy drives neurodegeneration in multiple sclerosis
Schattling B, Engler J, Volkmann C, Rothammer N, Woo M, Petersen M, Winkler I, Kaufmann M, Rosenkranz S, Fejtova A, Thomas U, Bose A, Bauer S, Träger S, Miller K, Brück W, Duncan K, Salinas G, Soba P, Gundelfinger E, Merkler D, Friese M
NAT NEUROSCI. 2019;22(6):887-896.

Letzte Aktualisierung aus dem FIS: 24.12.2024 - 03:47 Uhr