- Head of research group
Publications
A Comprehensive Analysis of Tn and STn Antigen Expression in Esophageal Adenocarcinoma
Mercanoglu B, Karstens K, Giannou A, Meiners J, Lücke J, Seeger P, Brackrock V, Güngör C, Izbicki J, Bockhorn M, Hackert T, Melling N, Wolters-Eisfeld G
CANCERS. 2024;16(2):.
Potential role of the bitter taste receptor T2R14 in the prolonged survival and enhanced chemoresponsiveness induced by apigenin
Stern L, Boehme L, Goetz M, Nitschke C, Giannou A, Zhang T, Güngör C, Reeh M, Izbicki J, Fliegert R, Hausen A, Giese N, Hackert T, Niv M, Heinrich S, Gaida M, Ghadban T
INT J ONCOL. 2023;62(1):.
Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer
Tintelnot J, Xu Y, Lesker T, Schönlein M, Konczalla L, Giannou A, Pelczar P, Kylies D, Puelles V, Bielecka A, Peschka M, Cortesi F, Riecken K, Jung M, Amend L, Bröring T, Trajkovic-Arsic M, Siveke J, Renné T, Zhang D, Boeck S, Strowig T, Uzunoglu F, Güngör C, Stein A, Izbicki J, Bokemeyer C, Sinn M, Kimmelman A, Huber S, Gagliani N
NATURE. 2023;615(7950):168-174.
KDM5 family of demethylases promotes CD44-mediated chemoresistance in pancreatic adenocarcinomas
Wang D, Zhang Y, Liao Z, Ge H, Güngör C, Li Y
SCI REP-UK. 2023;13(1):18250.
Unmasking metabolic dependencies in pancreatic cancer aberrant polyamine synthesis as a promising new therapeutic target
Wolters-Eisfeld G, Hackert T, Güngör C
SIGNAL TRANSDUCT TAR. 2023;8(1):.
Effective sealing of biliary and pancreatic fistulas with a novel biodegradable polyurethane-based tissue sealant patch
Bahar A, Goetz M, Uzunoglu F, Güngör C, Reeh M, Izbicki J, Bockhorn M, Heumann A
HPB. 2022;24(5):624-634.
Prognostic factors and individualized nomograms predicting overall survival in stage IV rectal cancer patients with different metastatic status: a SEER-based study
Ge H, Zhou Z, Li Y, Wang D, Güngör C
TRANSL CANCER RES. 2022;11(9):3141-3155.
Characterization of RARRES1 Expression on Circulating Tumor Cells as Unfavorable Prognostic Marker in Resected Pancreatic Ductal Adenocarcinoma Patients
Nitschke C, Markmann B, Tölle M, Kropidlowski J, Belloum Y, Goetz M, Schlüter H, Kwiatkowski M, Sinn M, Izbicki J, Pantel K, Güngör C, Uzunoglu F, Wikman H
CANCERS. 2022;14(18):.
The Survival Effect of Radiotherapy on Stage IIB/III Pancreatic Cancer Undergone Surgery in Different Age and Tumor Site Groups: A Propensity Scores Matching Analysis Based on SEER Database
Wang D, Ge H, Tian M, Li C, Zhao L, Pei Q, Tan F, Li Y, Ling C, Güngör C
FRONT ONCOL. 2022;12:.
The Extracellular Matrix - A Key Accomplice of Cancer Stem Cell Migration, Metastasis Formation, and Drug Resistance in PDAC: The Extracellular Matrix in Pancreatic Cancer
Wang D, Li Y, Ge H, Ghadban T, Reeh M, Güngör C
CANCERS. 2022;14(16):.
The survival impact of palliative radiotherapy on synchronous metastatic pancreatic ductal adenocarcinoma: metastatic site can serve for radiotherapy-decision
Xu B, Zhou Y, Pei Q, Tan F, Zhao L, Güngör C, Wang D, Li Y, Liu W, Zhou Z
J CANCER. 2022;13(2):385-392.
The survival impact of radiotherapy on synchronous metastatic rectal cancer: metastatic site can serve for radiotherapy-decision
Zhou Y, Wang D, Tan F, Zhou Z, Zhao L, Güngör C, Pei Q, Li Y, Liu W
J CANCER. 2022;13(7):2171-2178.
Survival effects of primary and metastatic surgical treatment in metastatic small intestinal tumors: A propensity score-matching study
Zhou Z, Ge H, Li Y, Wang D, Güngör C
PLOS ONE. 2022;17(6):.
Truncated O-GalNAc glycans impact on fundamental signaling pathways in pancreatic cancer
Hofmann B, Picksak A, Kwiatkowski M, Grupp K, Jücker M, Bachmann K, Mercanoglu B, Izbicki J, Kahlert C, Bockhorn M, Güngör C, Ewald F, Wolters-Eisfeld G
GLYCOBIOLOGY. 2021;2021:.
Accurate nomograms with excellent clinical value for locally advanced rectal cancer
Li Y, Liu D, Zhao L, Güngör C, Song X, Wang D, Liu W, Tan F
ANN TRANSL MED. 2021;9(4):296.
The Survival Effect of Radiotherapy on Stage II/III Rectal Cancer in Different Age Groups: Formulating Radiotherapy Decision-Making Based on Age
Li Y, Liu H, Zhou Y, Zhou Z, Liu W, Zhao L, Güngör C, Wang D, Pei Q, Pei H, Tan F
FRONT ONCOL. 2021;11:695640.
Follistatin-Like 3 Enhances Invasion and Metastasis via β-Catenin-Mediated EMT and Aerobic Glycolysis in Colorectal Cancer
Li Y, Tian M, Liu W, Wang D, Zhou Z, Pei Q, Huang Y, Tan F, Güngör C
FRONT CELL DEV BIOL. 2021;9:.
A novel risk-scoring system conducing to chemotherapy decision for patients with pancreatic ductal adenocarcinoma after pancreatectomy
Li Y, Tian M, Zhou Y, Tan F, Liu W, Zhao L, Perez D, Song X, Wang D, Nitschke C, Pei Q, Güngör C
J CANCER. 2021;12(14):4433-4442.
Serum midkine as non-invasive biomarker for detection and prognosis of non-small cell lung cancer
Stern L, Mueller E, Bellon E, Reeh M, Grotelüschen R, Guengoer C, Melling N, Goetz M, Perez D, Izbicki J, Rawnaq-Möllers T, Ghadban T
SCI REP-UK. 2021;11(1):.
Specific survival nomograms based on SEER database for small intestine adenocarcinoma
Wang D, Li C, Li Y, Liu W, Zhao L, Güngör C, Tan F, Zhou Y
ANN PALLIAT MED. 2021;10(7):7440-7457.
A Nomogram for Predicting Lymph Nodal Metastases in Patients with Appendiceal Cancers: An Analysis of SEER Database
Wang D, Liu C, Yan T, Li C, Güngör C, Yang Q, Xu Y, Zhao L, Pei Q, Tan F, Li Y
J INVEST SURG. 2021;34(8):924-930.
Neoadjuvant radiotherapy for locoregional Siewert type II gastroesophageal junction adenocarcinoma: A propensity scores matching analysis
Zhou Y, Tian M, Güngör C, Wang D
PLOS ONE. 2021;16(5):.
Biperiden and mepazine effectively inhibit MALT1 activity and tumor growth in pancreatic cancer
Konczalla L, Perez D, Wenzel N, Wolters-Eisfeld G, Klemp C, Lüddeke J, Wolski A, Landschulze D, Meier C, Buchholz A, Yao D, Hofmann B, Graß J, Spriestersbach S, Grupp K, Schumacher U, Betzel C, Kapis S, Nuguid T, Steinberg P, Püschel K, Sauter G, Bockhorn M, Uzunoglu F, Izbicki J, Güngör C, El Gammal A
INT J CANCER. 2020;146(6):1618-1630.
Nomograms predicting Overall Survival and Cancer-specific Survival for Synchronous Colorectal Liver-limited Metastasis
Li Y, Liu W, Zhao L, Güngör C, Xu Y, Song X, Wang D, Zhou Z, Zhou Y, Li C, Pei Q, Tan F, Pei H
J CANCER. 2020;11(21):6213-6225.
The Main Bottleneck for Non-Metastatic Pancreatic Adenocarcinoma in Past Decades: A Population-Based Analysis
Li Y, Liu W, Zhao L, Xu Y, Yan T, Yang Q, Pei Q, Güngör C
MED SCI MONITOR. 2020;26:e921515.
Establishment and Verification of Synchronous Metastatic Nomogram for Gastrointestinal Stromal Tumors (GISTs): A Population-Based Analysis
Li Y, Zhang G, Song X, Zhao L, Güngör C, Wang D, Liu W, Huang Y, Tan F
GASTROENT RES PRACT. 2020;2020:8493707.
Systematic analysis of the human tumor cell binding to human vs. murine E- and P-selectin under static vs. dynamic conditions
Starzonek S, Maar H, Labitzky V, Wicklein D, Rossdam C, Buettner F, Wolters-Eisfeld G, Guengoer C, Wagener C, Schumacher U, Lange T
GLYCOBIOLOGY. 2020;30(9):695-709.
Effect of neoadjuvant radiotherapy on survival of non-metastatic pancreatic ductal adenocarcinoma: a SEER database analysis
Wang D, Liu C, Zhou Y, Yan T, Li C, Yang Q, Xu Y, Zhao L, Pei Q, Tan F, Güngör C, Li Y
RADIAT ONCOL. 2020;15(1):107.
Predicting pathological complete response by comparing MRI-based radiomics pre- and postneoadjuvant radiotherapy for locally advanced rectal cancer
Li Y, Liu W, Pei Q, Zhao L, Güngör C, Zhu H, Song X, Li C, Zhou Z, Xu Y, Wang D, Tan F, Yang P, Pei H
CANCER MED-US. 2019;8(17):7244-7252.
The main contributor to the upswing of survival in locally advanced colorectal cancer: an analysis of the SEER database
Li Y, Zhao L, Güngör C, Tan F, Zhou Z, Li C, Song X, Wang D, Pei Q, Liu W
THER ADV GASTROENTER. 2019;12:1756284819862154.
EXPRESSION OF TN ANTIGEN PROMOTES PANCREATIC CARCINOGENESIS IN A TRANSGENIC MOUSE MODEL
Mercanoglu B, Wolters-Eisfeld G, Güngör C, Izbicki J, Bockhorn M
UNITED EUR GASTROENT. 2018.
Loss of complex O-glycosylation impairs exocrine pancreatic function and induces MODY8-like diabetes in mice
Wolters-Eisfeld G, Mercanoglu B, Hofmann B, Wolpers T, Schnabel C, Harder S, Steffen P, Bachmann K, Steglich B, Schrader J, Gagliani N, Schlüter H, Güngör C, Izbicki J, Wagener C, Bockhorn M
EXP MOL MED. 2018;50(10):1-13.
HRG/HER2/HER3 signaling promotes AhR-mediated Memo-1 expression and migration in colorectal cancer
Bogoevska V, Wolters-Eisfeld G, Hofmann B, El Gammal A, Mercanoglu B, Gebauer F, Vashist Y, Bogoevski D, Perez D, Gagliani N, Izbicki J, Bockhorn M, Güngör C
ONCOGENE. 2017;36(17):2394-2404.
Protein S100A8/A9: A Potential New Biomarker for Pancreatic Diseases
El Gammal A, Sturm J, Pinnschmidt H, Hofmann B, Bellon E, Ghadban T, Melling N, Bachmann K, Izbicki J, Bockhorn M, Güngör C, Perez D
Int J Clin Endocrinol Metab. 2017;3(1):023-028.
HSP90 is a promising target in gemcitabine and 5-fluorouracil resistant pancreatic cancer
Ghadban T, Dibbern J, Reeh M, Miro J, Tsui T, Wellner U, Izbicki J, Güngör C, Vashist Y
APOPTOSIS. 2017;22(3):369-380.
TRYPTOPHAN DEGRADATION AS AN ALTERNATIVE ENERGY SOURCE IN PANCREATIC CANCER
Güngör C, Mercanoglu B, Wolters-Eisfeld G, Izbicki J, Bockhorn M
UNITED EUR GASTROENT. 2017;5: Supplement 1.
Hypoxie induzierte und HIF1A vermittelte differentielle O-Glykosylierung reguliert onkogene Signalwege im duktalen Adenokarzinom des Pankreas
Mercanoglu B, Güngör C, Bockhorn M, Wolters-Eisfeld G
Z GASTROENTEROL. 2017;55(08):KV 222.
HYPOXIA INDUCED HIF1A-MEDIATED DIFFERENTIAL O-GALNAC GLYCOSYLATION DIRECTLY REGULATES SIGNALING PATHWAYS IN PANCREATIC CANCER
Mercanoglu B, Hofmann B, Güngör C, Izbicki J, Bockhorn M, Wolters-Eisfeld G
UNITED EUR GASTROENT. 2017.
Expression of Tn Antigen Causes Chronic Pancreatitis in a Transgenic Mouse Model
Mercanoglu B, Karstens K, Güngör C, Izbicki J, Bockhorn M, Wolters-Eisfeld G
EUR SURG RES. 2017.
EXPRESSION OF TN ANTIGEN CAUSES CHRONIC PANCREATITIS IN A TRANSGENIC MOUSE MODEL
Mercanoglu B, Karstens K, Güngör C, Izbicki J, Bockhorn M, Wolters-Eisfeld G
UNITED EUR GASTROENT. 2017.
Die Expression des Tn Antigens begünstigt die pankreatische Karzinogenese in einem transgenen Mausmodell
Mercanoglu B, Wolters-Eisfeld G, Güngör C, Izbicki J, Bockhorn M
Z GASTROENTEROL. 2017.
DIFFERENTIALLY O-GLYCOSYLATED CARBOXYL ESTER LIPASE CAUSES A MODY8-LIKE PHENOTYPE IN MICE
Mercanoglu B, Wolters-Eisfeld G, Güngör C, Izbicki J, Bockhorn M
UNITED EUR GASTROENT. 2017.
Hypoxia induced HIF1a-mediated O-GalNAc glycosylation of cytosolic O-GlcNAcylated proteins to regulate signaling pathways in pancreatic cancer.
Wolters-Eisfeld G, Mercanoglu B, Güngör C, Izbicki J, Bockhorn M
J CLIN ONCOL. 2017;35(15_suppl):e15739-e15739.
In vitro study comparing the efficacy of the water-soluble HSP90 inhibitors, 17-AEPGA and 17-DMAG, with that of the non‑water-soluble HSP90 inhibitor, 17-AAG, in breast cancer cell lines
Ghadban T, Jessen A, Reeh M, Dibbern J, Mahner S, Mueller V, Wellner U, Güngör C, Izbicki J, Vashist Y
INT J MOL MED. 2016;38(4):1296-302.
Relevance of Sp Binding Site Polymorphism in WWOX for Treatment Outcome in Pancreatic Cancer
Schirmer M, Lüske C, Roppel S, Schaudinn A, Zimmer C, Pflüger R, Haubrock M, Rapp J, Güngör C, Bockhorn M, Hackert T, Hank T, Strobel O, Werner J, Izbicki J, Johnsen S, Gaedcke J, Brockmöller J, Ghadimi B
JNCI-J NATL CANCER I. 2016;108(5):djv387.
COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer
Hofmann B, Schlüter L, Lange P, Mercanoglu B, Ewald F, Fölster A, Picksak A, Harder S, El Gammal A, Grupp K, Güngör C, Drenckhan A, Schlüter H, Wagener C, Izbicki J, Jücker M, Bockhorn M, Wolters-Eisfeld G
MOL CANCER. 2015;14(1):109.
Obesity research: Status quo and future outlooks
El Gammal A, Dupree A, Wolter S, Aberle J, Izbicki J, Güngör C, Mann O
World J of Transl Med. 2014;3(3):119-132.
The role of RANK-signaling in tumor cell proliferation and migration in pancreatic adenocarcinoma.
El Gammal A, Sander N, Aljonna F, Friedenberger H, Leonie K, Güngör C, Wolters-Eisfeld G, Hofmann B, Bockhorn M, Izbicki J, Perez D
2014. J Clin Oncol. suppl; abstr e15193.
Pancreatic cancer
Güngör C, Hofmann B, Wolters-Eisfeld G, Bockhorn M
BRIT J PHARMACOL. 2014;171(4):849-858.
ABO blood group IgM isoagglutinins interact with tumor-associated O-glycan structures in pancreatic cancer
Hofmann B, Stehr A, Dohrmann T, Güngör C, Herich L, Hiller J, Harder S, Ewald F, Gebauer F, Tachezy M, Precht C, Izbicki J, Bockhorn M, Wagener C, Wolters-Eisfeld G
CLIN CANCER RES. 2014;20(23):6117-26.
The multifunctional growth factor midkine promotes proliferation and migration in pancreatic cancer
Rawnaq T, Dietrich L, Wolters-Eisfeld G, Uzunoglu F, Vashist Y, Bachmann K, Simon R, Izbicki J, Bockhorn M, Güngör C
MOL CANCER RES. 2014;12(5):670-80.
EGFR intron-1 CA repeat polymorphism is a predictor of relapse and survival in complete resected only surgically treated esophageal cancer
Vashist Y, Trump F, Gebauer F, Kutup A, Güngör C, Kalinin V, Muddasar R, Vettorazzi E, Yekebas E, Brandt B, Pantel K, Izbicki J
TARGET ONCOL. 2014;9(1):43-52.
Functional activity of RLIM/Rnf12 is regulated by phosphorylation-dependent nucleocytoplasmic shuttling
Jiao B, Taniguchi-Ishigaki N, Güngör C, Peters M, Chen Y, Riethdorf S, Drung A, Ahronian L, Shin J, Pagnis R, Pantel K, Tachibana T, Lewis B, Johnsen S, Bach I
MOL BIOL CELL. 2013;24(19):3085-96.
VEGFR-2, CXCR-2 and PAR-1 germline polymorphisms as predictors of survival in pancreatic carcinoma
Uzunoglu F, Kolbe J, Wikman H, Güngör C, Bohn B, Nentwich M, Reeh M, König A, Bockhorn M, Kutup A, Mann O, Izbicki J, Vashist Y
ANN ONCOL. 2013;24(5):1282-90.
Vascular endothelial growth factor receptor 2 gene polymorphisms as predictors for tumor recurrence and overall survival in non-small-cell lung cancer.
Uzunoglu F, Kaufmann C, Wikman H, Güngör C, Bohn B, Nentwich M, Reeh M, Pantel K, Bockhorn M, Kutup A, Mann O, Izbicki J, Vashist Y
ANN SURG ONCOL. 2012;19(7):2159-2168.
Notch signaling activated by replication stress-induced expression of midkine drives epithelial-mesenchymal transition and chemoresistance in pancreatic cancer.
Güngör C, Zander H, Harms-Effenberger K, Vashist Y, Kalinina T, Izbicki J, Yekebas E, Bockhorn M
CANCER RES. 2011;71(14):5009-5019.
Insulin-like growth factor-1 receptor as a novel prognostic marker and its implication as a cotarget in the treatment of human adenocarcinoma of the esophagus.
Kalinina T, Bockhorn M, Kaifi J, Thieltges S, Güngör C, Harms-Effenberger K, Strelow A, Reichelt U, Sauter G, Pantel K, Izbicki J, Yekebas E
INT J CANCER. 2010;127(8):1931-1940.
Establishment and characterization of a new human pancreatic adenocarcinoma cell line with high metastatic potential to the lung.
Kalinina T, Güngör C, Thieltges S, Möller-Krull M, Murga-Penas E, Wicklein D, Streichert T, Schumacher U, Kalinin V, Simon R, Otto B, Dierlamm J, Schwarzenbach H, Harms-Effenberger K, Bockhorn M, Izbicki J, Yekebas E
BMC CANCER. 2010;10:295.
Letzte Aktualisierung aus dem FIS: 25.12.2024 - 04:04 Uhr