Synthesis and new DNA targeting activity of 6- and 7-tert-butylfascaplysins
Dyshlovoy S, Mansour W, Ramm N, Hauschild J, Zhidkov M, Kriegs M, Zielinski A, Hoffer K, Busenbender T, Glumakova K, Spirin P, Prassolov V, Tilki D, Graefen M, Bokemeyer C, von Amsberg G
SCI REP-UK. 2024;14(1):11788.

Rhizochalinin Exhibits Anticancer Activity and Synergizes with EGFR Inhibitors in Glioblastoma In Vitro Models
Dyshlovoy S, Hauschild J, Venz S, Krisp C, Kolbe K, Zapf S, Heinemann S, Fita K, Shubina L, Makarieva T, Guzii A, Rohlfing T, Kaune M, Busenbender T, Mair T, Moritz M, Poverennaya E, Schlüter H, Serdyuk V, Stonik V, Dierlamm J, Bokemeyer C, Mohme M, Westphal M, Lamszus K, von Amsberg G, Maire C
MOL PHARMACEUT. 2023;20(10):4994-5005.

New Marine Fungal Deoxy-14,15-Dehydroisoaustamide Resensitizes Prostate Cancer Cells to Enzalutamide
Dyshlovoy S, Zhuravleva O, Hauschild J, Busenbender T, Pelageev D, Yurchenko A, Khudyakova Y, Antonov A, Graefen M, Bokemeyer C, von Amsberg G
MAR DRUGS. 2023;21(1):.

New Bioactive β-Resorcylic Acid Derivatives from the Alga-Derived Fungus Penicillium antarcticum KMM 4685
Leshchenko E, Antonov A, Borkunov G, Hauschild J, Zhuravleva O, Khudyakova Y, Menshov A, Popov R, Kim N, Graefen M, Bokemeyer C, von Amsberg G, Yurchenko A, Dyshlovoy S
MAR DRUGS. 2023;21(3):.

Anticancer Activity of the Marine Triterpene Glycoside Cucumarioside A2-2 in Human Prostate Cancer Cells
Menchinskaya E, Dyshlovoy S, Venz S, Jacobsen C, Hauschild J, Rohlfing T, Silchenko A, Avilov S, Balabanov S, Bokemeyer C, Aminin D, von Amsberg G, Honecker F
MAR DRUGS. 2023;22(1):.

Salvage Chemotherapy with Cisplatin, Ifosfamide, and Paclitaxel in Aggressive Variant of Metastatic Castration-Resistant Prostate Cancer
Amsberg G, Zilles M, Mansour W, Gild P, Alsdorf W, Kaune M, Böckelmann L, Hauschild J, Krisp C, Rohlfing T, Saygi C, Alawi M, Zielinski A, Langebrake C, Su X, Perner S, Tilki D, Schluter H, Graefen M, Dyshlovoy S, Bokemeyer C
INT J MOL SCI. 2022;23(23):.

Cytotoxic N-Methylpretrichodermamide B Reveals Anticancer Activity and Inhibits P-Glycoprotein in Drug-Resistant Prostate Cancer Cells
Dyshlovoy S, Busenbender T, Hauschild J, Girich E, Kriegs M, Hoffer K, Graefen M, Yurchenko A, Bokemeyer C, Amsberg G
MAR DRUGS. 2022;20(10):.

New Guanidine Alkaloids Batzelladines O and P from the Marine Sponge Monanchora pulchra Induce Apoptosis and Autophagy in Prostate Cancer Cells
Dyshlovoy S, Shubina L, Makarieva T, Guzii A, Hauschild J, Strewinsky N, Berdyshev D, Kudryashova E, Menshov A, Popov R, Dmitrenok P, Graefen M, Bokemeyer C, Amsberg G
MAR DRUGS. 2022;20(12):.

New diterpenes from the marine sponge Spongionella sp. overcome drug resistance in prostate cancer by inhibition of P-glycoprotein
Dyshlovoy S, Shubina L, Makarieva T, Hauschild J, Strewinsky N, Guzii A, Menshov A, Popov R, Grebnev B, Busenbender T, Oh-Hohenhorst S, Maurer T, Tilki D, Graefen M, Bokemeyer C, Stonik V, von Amsberg G
SCI REP-UK. 2022;12(1):.

Meroantarctines A-C, Meroterpenoids with Rearranged Skeletons from the Alga-Derived Fungus Penicillium antarcticum KMM 4685 with Potent p-Glycoprotein Inhibitory Activity
Leshchenko E, Antonov A, Dyshlovoy S, Berdyshev D, Hauschild J, Zhuravleva O, Menshov A, Kirichuk N, Popov R, Gerasimenko A, Udovenko A, Graefen M, Bokemeyer C, von Amsberg G, Yurchenko A
J NAT PROD. 2022;85(12):2746-2752.

Study of Structure-Activity Relationships of the Marine Alkaloid Fascaplysin and Its Derivatives as Potent Anticancer Agents
Zhidkov M, Kaune M, Kantemirov A, Smirnova P, Spirin P, Sidorova M, Stadnik S, Shyrokova E, Kaluzhny D, Tryapkin O, Busenbender T, Hauschild J, Rohlfing T, Prassolov V, Bokemeyer C, Graefen M, von Amsberg G, Dyshlovoy S
MAR DRUGS. 2022;20(3):.

Activity of New Synthetic (2-Chloroethylthio)-1,4-naphthoquinones in Prostate Cancer Cells
Dyshlovoy S, Pelageev D, Jakob L, Borisova K, Hauschild J, Busenbender T, Kaune M, Khmelevskaya E, Graefen M, Bokemeyer C, Anufriev V, von Amsberg G
PHARMACEUTICALS-BASE. 2021;14(10):949.

Efficacy and Mechanism of Action of Marine Alkaloid 3,10-Dibromofascaplysin in Drug-Resistant Prostate Cancer Cells
Dyshlovoy S, Kaune M, Hauschild J, Kriegs M, Hoffer K, Busenbender T, Smirnova P, Zhidkov M, Poverennaya E, Oh-Hohenhorst S, Spirin P, Prassolov V, Tilki D, Bokemeyer C, Graefen M, von Amsberg G
MAR DRUGS. 2020;18(12):.

Marine alkaloid monanchoxymycalin C: a new specific activator of JNK1/2 kinase with anticancer properties
Dyshlovoy S, Kaune M, Kriegs M, Hauschild J, Busenbender T, Shubina L, Makarieva T, Hoffer K, Bokemeyer C, Graefen M, Stonik V, von Amsberg G
SCI REP-UK. 2020;10(1):13178.

Urupocidin C: a new marine guanidine alkaloid which selectively kills prostate cancer cells via mitochondria targeting
Dyshlovoy S, Kudryashova E, Kaune M, Makarieva T, Shubina L, Busenbender T, Denisenko V, Popov R, Hauschild J, Fedorov S, Bokemeyer C, Graefen M, Stonik V, von Amsberg G
SCI REP-UK. 2020;10(1):9764.

Inspired by Sea Urchins: Warburg Effect Mediated Selectivity of Novel Synthetic Non-Glycoside 1,4-Naphthoquinone-6S-Glucose Conjugates in Prostate Cancer
Dyshlovoy S, Pelageev D, Hauschild J, Sabutskii Y, Khmelevskaya E, Krisp C, Kaune M, Venz S, Borisova K, Busenbender T, Denisenko V, Schlüter H, Bokemeyer C, Graefen M, Polonik S, Anufriev V, Amsberg G
MAR DRUGS. 2020;18(5):.

Polyphenolic Compounds from Lespedeza Bicolor Root Bark Inhibit Progression of Human Prostate Cancer Cells via Induction of Apoptosis and Cell Cycle Arrest
Dyshlovoy S, Tarbeeva D, Fedoreyev S, Busenbender T, Kaune M, Veselova M, Kalinovskiy A, Hauschild J, Grigorchuk V, Kim N, Bokemeyer C, Graefen M, Gorovoy P, von Amsberg G
BIOMOLECULES. 2020;10(3):.

Successful Targeting of the Warburg Effect in Prostate Cancer by Glucose-Conjugated 1,4-Naphthoquinones
Dyshlovoy S, Pelageev D, Hauschild J, Borisova K, Kaune M, Krisp C, Venz S, Sabutskii Y, Khmelevskaya E, Busenbender T, Denisenko V, Pokhilo N, Atopkina L, Graefen M, Schlüter H, Stonik V, Bokemeyer C, Anufriev V, von Amsberg G
CANCERS. 2019;11(11):.

Synthesis and anticancer activity of the derivatives of marine compound rhizochalin in castration resistant prostate cancer
Dyshlovoy S, Otte K, Tabakmakher K, Hauschild J, Makarieva T, Shubina L, Fedorov S, Bokemeyer C, Stonik V, von Amsberg G
ONCOTARGET. 2018;9(24):16962-16973.

The marine triterpene glycoside frondoside A induces p53-independent apoptosis and inhibits autophagy in urothelial carcinoma cells
Dyshlovoy S, Madanchi R, Hauschild J, Otte K, Alsdorf W, Schumacher U, Kalinin V, Silchenko A, Avilov S, Honecker F, Stonik V, Bokemeyer C, von Amsberg G
BMC CANCER. 2017;17(1):93.

Proteomic-based investigations on the mode of action of the marine anticancer compound rhizochalinin
Dyshlovoy S, Otte K, Venz S, Hauschild J, Junker H, Makarieva T, Balabanov S, Alsdorf W, Madanchi R, Honecker F, Bokemeyer C, Stonik V, von Amsberg G
PROTEOMICS. 2017;17(11):.

Frondoside A induces AIF-associated caspase-independent apoptosis in Burkitt lymphoma cells
Dyshlovoy S, Rast S, Hauschild J, Otte K, Alsdorf W, Madanchi R, Kalinin V, Silchenko A, Avilov S, Dierlamm J, Honecker F, Stonik V, Bokemeyer C, von Amsberg G
LEUKEMIA LYMPHOMA. 2017;58(12):2905-2915.

The marine triterpene glycoside frondoside A exhibits activity in vitro and in vivo in prostate cancer
Dyshlovoy S, Menchinskaya E, Venz S, Rast S, Amann K, Hauschild J, Otte K, Kalinin V, Silchenko A, Avilov S, Alsdorf W, Madanchi R, Bokemeyer C, Schumacher U, Walther R, Aminin D, Fedorov S, Shubina L, Stonik V, Balabanov S, Honecker F, von Amsberg G
INT J CANCER. 2016;138(10):2450-65.

Marine compound rhizochalinin shows high in vitro and in vivo efficacy in castration resistant prostate cancer
Dyshlovoy S, Otte K, Alsdorf W, Hauschild J, Lange T, Venz S, Bauer C, Bähring R, Amann K, Mandanchi R, Schumacher U, Schröder-Schwarz J, Makarieva T, Guzii A, Tabakmakher K, Fedorov S, Shubina L, Kasheverov I, Ehmke H, Steuber T, Stonik V, Bokemeyer C, Honecker F, von Amsberg G
ONCOTARGET. 2016;7(43):69703 - 69717.

Guanidine Alkaloids from the Marine Sponge Monanchora pulchra Show Cytotoxic Properties and Prevent EGF-Induced Neoplastic Transformation in Vitro
Dyshlovoy S, Tabakmakher K, Hauschild J, Shchekaleva R, Otte K, Guzii A, Makarieva T, Kudryashova E, Fedorov S, Shubina L, Bokemeyer C, Honecker F, Stonik V, von Amsberg G
MAR DRUGS. 2016;14(7):E133.

Anti-migratory activity of marine alkaloid monanchocidin A - proteomics-based discovery and confirmation
Dyshlovoy S, Venz S, Hauschild J, Tabakmakher K, Otte K, Madanchi R, Walther R, Guzii A, Makarieva T, Shubina L, Fedorov S, Stonik V, Bokemeyer C, Balabanov S, Honecker F, von Amsberg G
PROTEOMICS. 2016;16(10):1590-603.

Cabazitaxel overcomes cisplatin resistance in germ cell tumour cells
Gerwing M, Jacobsen C, Dyshlovoy S, Hauschild J, Rohlfing T, Oing C, Venz S, Oldenburg J, Oechsle K, Bokemeyer C, von Amsberg G, Honecker F
J CANCER RES CLIN. 2016;142(9):1979-94.

Activity of nintedanib in germ cell tumors
Steinemann G, Jacobsen C, Gerwing M, Hauschild J, Amsberg G, Höpfner M, Nitzsche B, Honecker F
ANTI-CANCER DRUG. 2016;27(2):89-98.

Marine alkaloid Monanchocidin a overcomes drug resistance by induction of autophagy and lysosomal membrane permeabilization
Dyshlovoy S, Hauschild J, Amann K, Tabakmakher K, Venz S, Walther R, Guzii A, Makarieva T, Shubina L, Fedorov S, Stonik V, Bokemeyer C, Balabanov S, Honecker F, Amsberg G
ONCOTARGET. 2015;6(19):17328-41.

Regulation of tissue factor in NT2 germ cell tumor cells by cisplatin chemotherapy
Jacobsen C, Oechsle K, Hauschild J, Steinemann G, Spath B, Bokemeyer C, Ruf W, Honecker F, Langer F
THROMB RES. 2015;136(3):673-81.

Combination therapy targeting integrins reduces glioblastoma tumor growth through antiangiogenic and direct antitumor activity and leads to activation of the pro-proliferative prolactin pathway
Oliveira Ferrer L, Wellbrock J, Bartsch U, Penas E, Hauschild J, Klokow M, Bokemeyer C, Fiedler W, Schuch G
MOL CANCER. 2013;12(1):144.

The metabolite 3-hydroxiglutaric acid effectively reduces glioblastoma growth in vivo by affecting the structural integrity of tumor vasculature.
Oliveira-Ferrer L, Wellbrock J, Balabanov M, Klockow M, Hauschild J, Bokemeyer C, Fiedler W, Ergun S, Schuch G
CANCER LETT. 2012;326(2):161-167.

LINE-1 retrotransposition events affect endothelial proliferation and migration
Banaz-Yaşar F, Steffen G, Hauschild J, Bongartz B, Schumann G, Ergün S
HISTOCHEM CELL BIOL. 2010;134(6):581-9.

Smoothing and passivation of special Si(111) substrates: studied by SPV, PL, AFM and SEM measurements.
Angermann H, Rappich J, Sieber I, Hübener K, Hauschild J
ANAL BIOANAL CHEM. 2008;390(6):1463-1470.

Cilengitide induces cellular detachment and apoptosis in endothelial and glioma cells mediated by inhibition of FAK/src/AKT pathway.
Oliveira-Ferrer L, Hauschild J, Fiedler W, Bokemeyer C, Nippgen J, Celik I, Schuch G
J EXP CLIN CANC RES. 2008;27:86.

Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion
Arakawa H, Hauschild J, Buerstedde J
SCIENCE. 2002;295(5558):1301-6.

Letzte Aktualisierung aus dem FIS: 23.12.2024 - 23:36 Uhr