Master corepressor inactivation through multivalent SLiM-induced polymerization mediated by the oncogene suppressor RAI2
Goradia N, Werner S, Mullapudi E, Greimeier S, Bergmann L, Lang A, Mertens H, Węglarz A, Sander S, Chojnowski G, Wikman H, Ohlenschläger O, von Amsberg G, Pantel K, Wilmanns M
NAT COMMUN. 2024;15(1):5241.

Detection of Multiple HPV Types in Liquid Biopsies of Cervical Neoplasia
Herbst J, Vohl V, Krajina M, Leffers M, Kropidlowski J, Prieske K, Jaeger A, Oliveira-Ferrer L, Schmalfeldt B, Goy Y, Burandt E, Pantel K, Vollmert C, Sartori A, Woelber L, Effenberger K, Wikman H
CLIN CHEM. 2024;70(1):285-296.

PIK3CA Hotspot Mutations in Saliva as a Diagnostic Marker in Oral Squamous Cell Carcinoma Patients
Krüger K, Grust A, Muallah D, Patenge A, Wikman H, Mesa M, Knust E, Sartori A, Smeets R, Kluwe L, Friedrich R, Burg S
ANTICANCER RES. 2024;44(6):2369-2376.

KRAS and GNAS mutations in cell-free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms-an observational pilot study
Nitschke C, Tölle M, Walter P, Meißner K, Goetz M, Kropidlowski J, Berger A, Izbicki J, Nickel F, Hackert T, Pantel K, Wikman H, Uzunoglu F
MOL ONCOL. 2024 [Epub ahead of print].

Frequency and Prognostic Value of Circulating Tumor Cells in Cancer of Unknown Primary
Pouyiourou M, Bochtler T, Coith C, Wikman H, Kraft B, Hielscher T, Stenzinger A, Riethdorf S, Pantel K, Krämer A
CLIN CHEM. 2024;70(1):297-306.

HERC5 downregulation in non-small cell lung cancer is associated with altered energy metabolism and metastasis
Schneegans S, Löptien J, Mojzisch A, Loreth D, Kretz O, Raschdorf C, Hanssen A, Gocke A, Siebels B, Gunasekaran K, Ding Y, Oliveira-Ferrer L, Brylka L, Schinke T, Schlüter H, Paatero I, Voß H, Werner S, Pantel K, Wikman H
J EXP CLIN CANC RES. 2024;43(1):110.

Mutation analysis in individual circulating tumor cells depicts intratumor heterogeneity in melanoma
Sementsov M, Ott L, Kött J, Sartori A, Lusque A, Degenhardt S, Segier B, Heidrich I, Volkmer B, Greinert R, Mohr P, Simon R, Stadler J, Irwin D, Koch C, Andreas A, Deitert B, Thewes V, Trumpp A, Schneeweiss A, Belloum Y, Peine S, Wikman H, Riethdorf S, Schneider S, Gebhardt C, Pantel K, Keller L
EMBO MOL MED. 2024;16(7):1560-1578.

Comparative evaluation of PD-L1 expression in cytology imprints, circulating tumour cells and tumour tissue in non-small cell lung cancer patients
Abdo M, Belloum Y, Heigener D, Welker L, von Weihe S, Schmidt M, Heuer-Olewinski N, Watermann I, Szewczyk M, Kropidlowski J, Pereira-Veiga T, Elmas H, Perner S, Steurer S, Wikman H, Pantel K, Reck M
MOL ONCOL. 2023;17(5):737-746.

Label Efficient Classification in Liquid Biopsy Data by Self-supervision
Husseini H, Nielsen M, Pantel K, Wikman H, Riethdorf S, Werner R
2023. Bildverarbeitung für die Medizin 2023. Deserno T, Handels H, Maier A, Maier-Hein K, Palm C, Tolxdorff T (Hrsg.). 1. Aufl. Springer Vieweg, 261-266.

Detection and Monitoring of Tumor-Derived Mutations in Circulating Tumor DNA Using the UltraSEEK Lung Panel on the MassARRAY System in Metastatic Non-Small Cell Lung Cancer Patients
Leest P, Janning M, Rifaela N, Azpurua M, Kropidlowski J, Loges S, Lozano N, Sartori A, Irwin D, Lamy P, Hiltermann T, Groen H, Pantel K, Kempen L, Wikman H, Schuuring E
INT J MOL SCI. 2023;24(17):.

Peripheral and Portal Venous KRAS ctDNA Detection as Independent Prognostic Markers of Early Tumor Recurrence in Pancreatic Ductal Adenocarcinoma
Nitschke C, Markmann B, Walter P, Badbaran A, Tölle M, Kropidlowski J, Belloum Y, Goetz M, Bardenhagen J, Stern L, Tintelnot J, Schönlein M, Sinn M, van der Leest P, Simon R, Heumann A, Izbicki J, Pantel K, Wikman H, Uzunoglu F
CLIN CHEM. 2023;69(3):295-307.

RNF40 epigenetically modulates glycolysis to support the aggressiveness of basal-like breast cancer
Prokakis E, Jansari S, Boshnakovska A, Wiese M, Kusch K, Kramm C, Dullin C, Rehling P, Glatzel M, Pantel K, Wikman H, Johnsen S, Gallwas J, Wegwitz F
CELL DEATH DIS. 2023;14(9):641.

The role of the desmosomal protein desmocollin 2 in tumour progression in triple negative breast cancer patients
Reimer F, Bryan S, Legler K, Karn T, Eppenberger-Castori S, Matschke J, Pereira-Veiga T, Wikman H, Witzel I, Müller V, Schmalfeldt B, Milde-Langosch K, Schumacher U, Stürken C, Oliveira-Ferrer L
CANCER CELL INT. 2023;23(1):47.

Expression Patterns and Corepressor Function of Retinoic Acid-induced 2 in Prostate Cancer
Besler K, Węglarz A, Keller L, von Amsberg G, Bednarz-Knoll N, Offermann A, Stoupiec S, Eltze E, Semjonow A, Boettcher L, Schneegans S, Perner S, Hauch S, Todenhöfer T, Peine S, Pantel K, Wikman H, Werner S
CLIN CHEM. 2022;68(7):973-983.

Spine Metastases in Immunocompromised Mice after Intracardiac Injection of MDA-MB-231-SCP2 Breast Cancer Cells
Brylka L, Jähn-Rickert K, Baranowsky A, Neven M, Horn M, Yorgan T, Wikman H, Werner S, Lübke A, Amling M, Busse B, Pantel K, Schinke T
CANCERS. 2022;14(3):.

Tumor-Stroma Interaction in PDAC as a New Approach for Liquid Biopsy and its Potential Clinical Implications
Götze J, Nitschke C, Uzunoglu F, Pantel K, Sinn M, Wikman H
FRONT CELL DEV BIOL. 2022;10:.

Clinical applications and utility of cell-free DNA-based liquid biopsy analyses in cervical cancer and its precursor lesions
Herbst J, Pantel K, Effenberger K, Wikman H
BRIT J CANCER. 2022;127(8):1403-1410.

Decellularized In Vitro Capillaries for Studies of Metastatic Tendency and Selection of Treatment
Huttala O, Loreth D, Staff S, Tanner M, Wikman H, Ylikomi T
BIOMEDICINES. 2022;10(2):.

Combined Liquid Biopsy Methylation Analysis of CADM1 and MAL in Cervical Cancer Patients
Leffers M, Herbst J, Kropidlowski J, Prieske K, Bohnen A, Peine S, Jaeger A, Prieske K, Goy Y, Schmalfeldt B, Pantel K, Wölber L, Effenberger K, Wikman H
CANCERS. 2022;14(16):.

Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism
Monteiro C, Miarka L, Perea-García M, Priego N, García-Gómez P, Álvaro-Espinosa L, de Pablos-Aragoneses A, Yebra N, Retana D, Baena P, Fustero-Torre C, Graña-Castro O, Troulé K, Caleiras E, Tezanos P, Muela P, Cintado E, Trejo J, Sepúlveda J, González-León P, Jiménez-Roldán L, Moreno L, Esteban O, Pérez-Núñez Á, Hernández-Lain A, Mazarico Gallego J, Ferrer I, Suárez R, Garrido-Martín E, Paz-Ares L, Dalmasso C, Cohen-Jonathan Moyal E, Siegfried A, Hegarty A, Keelan S, Varešlija D, Young L, Mohme M, Goy Y, Wikman H, Fernández-Alén J, Blasco G, Alcázar L, Cabañuz C, Grivennikov S, Ianus A, Shemesh N, Faria C, Lee R, Lorigan P, Le Rhun E, Weller M, Soffietti R, Bertero L, Ricardi U, Bosch-Barrera J, Sais E, Teixidor E, Hernández-Martínez A, Calvo A, Aristu J, Martin S, Gonzalez A, Adler O, Erez N, Valiente M
NAT MED. 2022;28(4):752-765.

Circulating Cancer Associated Macrophage-like Cells as a Potential New Prognostic Marker in Pancreatic Ductal Adenocarcinoma
Nitschke C, Markmann B, Konczalla L, Kropidlowski J, Pereira-Veiga T, Scognamiglio P, Schönrock M, Sinn M, Tölle M, Izbicki J, Pantel K, Uzunoglu F, Wikman H
BIOMEDICINES. 2022;10(11):.

Characterization of RARRES1 Expression on Circulating Tumor Cells as Unfavorable Prognostic Marker in Resected Pancreatic Ductal Adenocarcinoma Patients
Nitschke C, Markmann B, Tölle M, Kropidlowski J, Belloum Y, Goetz M, Schlüter H, Kwiatkowski M, Sinn M, Izbicki J, Pantel K, Güngör C, Uzunoglu F, Wikman H
CANCERS. 2022;14(18):.

Circulating tumor cell-blood cell crosstalk: Biology and clinical relevance
Pereira-Veiga T, Schneegans S, Pantel K, Wikman H
CELL REP. 2022;40(9):.

Clinical determinants impacting overall survival of patients with operable brain metastases from non-small cell lung cancer
Piffko A, Asey B, Dührsen L, Ristow I, Salamon J, Wikman H, Maire C, Lamszus K, Westphal M, Sauvigny T, Mohme M
FRONT ONCOL. 2022;12:.

Circulating tumor cells and extracellular vesicles as liquid biopsy markers in neuro-oncology: prospects and limitations
Westphal M, Pantel K, Ricklefs F, Maire C, Riethdorf S, Mohme M, Wikman H, Lamszus K
NEURO-ONCOL ADV. 2022;4(Suppl 2):ii45-ii52.

Emerging Insights into Keratin 16 Expression during Metastatic Progression of Breast Cancer
Elazezy M, Schwentesius S, Stegat L, Wikman H, Werner S, Mansour W, Failla A, Peine S, Müller V, Thiery J, Ebrahimi Warkiani M, Pantel K, Joosse S
CANCERS. 2021;13(15):.

Clinical relevance of blood-based ctDNA analysis: mutation detection and beyond
Keller L, Belloum Y, Wikman H, Pantel K
BRIT J CANCER. 2021;124(2):345-358.

CD74 and CD44 Expression on CTCs in Cancer Patients with Brain Metastasis
Loreth D, Schuette M, Zinke J, Mohme M, Piffko A, Schneegans S, Stadler J, Janning M, Loges S, Joosse S, Lamszus K, Westphal M, Müller V, Glatzel M, Matschke J, Gebhardt C, Schneider S, Belczacka I, Volkmer B, Greinert R, Yaspo M, Harter P, Pantel K, Wikman H
INT J MOL SCI. 2021;22(13):.

P02.01 A strategy to personalize the use of radiation in patients with brain metastasis based on S100A9-mediated resistance
Miarka L, Monteiro C, Dalmasso C, Yebra N, Fustero-Torre C, Hegarty A, Keelan S, Goy Y, Mohme M, Caleiras E, Vareslija D, Young L, Soffietti R, Fernández-Alén J, Blasco G, Alcázar L, Sepúlveda J, Pérez A, Lain A, Siegfried A, Wikman H, Cohen-Jonathan Moyal E, Valiente M
NEURO-ONCOLOGY. 2021;23(Supplement_2):ii17-ii17.

Decreased PRC2 activity supports the survival of basal-like breast cancer cells to cytotoxic treatments
Mieczkowska I, Pantelaiou-Prokaki G, Prokakis E, Schmidt G, Müller-Kirschbaum L, Werner M, Sen M, Velychko T, Jannasch K, Dullin C, Napp J, Pantel K, Wikman H, Wiese M, Kramm C, Alves F, Wegwitz F
CELL DEATH DIS. 2021;12(12):.

Proficiency Testing to Assess Technical Performance for CTC-Processing and Detection Methods in CANCER-ID
Neves R, Ammerlaan W, Andree K, Bender S, Cayrefourcq L, Driemel C, Koch C, Luetke-Eversloh M, Oulhen M, Rossi E, Alix-Panabières C, Betsou F, Farace F, Riethdorf S, Schlange T, Wikman H, Zamarchi R, Pantel K, Terstappen L, Stoecklein N
CLIN CHEM. 2021;67(4):631-641.

Integrin alpha5 in human breast cancer is a mediator of bone metastasis and a therapeutic target for the treatment of osteolytic lesions
Pantano F, Croset M, Driouch K, Bednarz-Knoll N, Iuliani M, Ribelli G, Bonnelye E, Wikman H, Geraci S, Bonin F, Simonetti S, Vincenzi B, Hong S, Sousa S, Pantel K, Tonini G, Santini D, Clézardin P
ONCOGENE. 2021;40(7):1284-1299.

Discovery of Targetable Genetic Alterations in NSCLC Patients with Different Metastatic Patterns Using a MassARRAY-Based Circulating Tumor DNA Assay
Belloum Y, Janning M, Mohme M, Simon R, Kropidlowski J, Sartori A, Irwin D, Westphal M, Lamszus K, Loges S, Riethdorf S, Pantel K, Wikman H
CELLS-BASEL. 2020;9(11):.

Multicenter Evaluation of Circulating Cell-Free DNA Extraction and Downstream Analyses for the Development of Standardized (Pre)analytical Work Flows
Lampignano R, Neumann M, Weber S, Kloten V, Herdean A, Voss T, Groelz D, Babayan A, Tibbesma M, Schlumpberger M, Chemi F, Rothwell D, Wikman H, Galizzi J, Bergheim I, Russnes H, Mussolin B, Bonin S, Voigt C, Musa H, Pinzani P, Lianidou E, Brady G, Speicher M, Pantel K, Betsou F, Schuuring E, Kubista M, Ammerlaan W, Sprenger-Haussels M, Schlange T, Heitzer E
CLIN CHEM. 2020;66(1):149-160.

Prevention of DNA Replication Stress by CHK1 Leads to Chemoresistance Despite a DNA Repair Defect in Homologous Recombination in Breast Cancer
Meyer F, Becker S, Classen S, Parplys A, Mansour W, Riepen B, Timm S, Ruebe C, Jasin M, Wikman H, Petersen C, Rothkamm K, Borgmann K
CELLS-BASEL. 2020;9(1):.

ALCAM contributes to brain metastasis formation in non-small-cell lung cancer through interaction with the vascular endothelium
Münsterberg J, Loreth D, Brylka L, Werner S, Karbanova J, Gandrass M, Schneegans S, Besler K, Hamester F, Robador J, Bauer A, Werner Schneider S, Wrage M, Lamszus K, Matschke J, Vashist Y, Uzunoglu G, Steurer S, Horst A, Oliveira-Ferrer L, Glatzel M, Schinke T, Corbeil D, Pantel K, Maire C, Wikman H
NEURO-ONCOLOGY. 2020;22(7):955-966.

Exploiting Chromosomal Instability of PTEN-Deficient Triple-Negative Breast Cancer Cell Lines for the Sensitization against PARP1 Inhibition in a Replication-Dependent Manner
Rieckhoff J, Meyer F, Classen S, Zielinski A, Riepen B, Wikman H, Petersen C, Rothkamm K, Borgmann K, Parplys A
CANCERS. 2020;12(10):.

Pre-analytical factors affecting the establishment of a single tube assay for multiparameter liquid biopsy detection in melanoma patients
Schneegans S, Lück L, Besler K, Bluhm L, Stadler J, Staub J, Greinert R, Volkmer B, Kubista M, Gebhardt C, Sartori A, Irwin D, Serkkola E, Af Hällström T, Lianidou E, Sprenger-Haussels M, Hussong M, Mohr P, Schneider S, Shaffer J, Pantel K, Wikman H
MOL ONCOL. 2020;14(5):1001-1015.

Determination of PD-L1 Expression in Circulating Tumor Cells of NSCLC Patients and Correlation with Response to PD-1/PD-L1 Inhibitors
Janning M, Kobus F, Babayan A, Wikman H, Velthaus J, Bergmann S, Schatz S, Falk M, Berger L, Böttcher L, Päsler S, Gorges T, O'Flaherty L, Hille C, Joosse S, Simon R, Tiemann M, Bokemeyer C, Reck M, Riethdorf S, Pantel K, Loges S
CANCERS. 2019;11(6):.

EPAC-lung: pooled analysis of circulating tumour cells in advanced non-small cell lung cancer
Lindsay C, Blackhall F, Carmel A, Fernandez-Gutierrez F, Gazzaniga P, Groen H, Hiltermann T, Krebs M, Loges S, López-López R, Muinelo-Romay L, Pantel K, Priest L, Riethdorf S, Rossi E, Terstappen L, Wikman H, Soria J, Farace F, Renehan A, Dive C, Besse B, Michiels S
EUR J CANCER. 2019;117:60-68.

Clonality of circulating tumor cells in breast cancer brain metastasis patients
Riebensahm C, Joosse S, Mohme M, Hanssen A, Matschke J, Goy Y, Witzel I, Lamszus K, Kropidlowski J, Petersen C, Kolb-Kokocinski A, Sauer S, Borgmann K, Glatzel M, Müller V, Westphal M, Riethdorf S, Pantel K, Wikman H
BREAST CANCER RES. 2019;21(1):101.

EGFR and HER3 expression in circulating tumor cells and tumor tissue from non-small cell lung cancer patients
Scharpenseel H, Hanssen A, Loges S, Mohme M, Bernreuther C, Peine S, Lamszus K, Goy Y, Petersen C, Westphal M, Glatzel M, Riethdorf S, Pantel K, Wikman H
SCI REP-UK. 2019;9(1):7406.

Identification of a High-Level MET Amplification in CTCs and cfTNA of an ALK-Positive NSCLC Patient Developing Evasive Resistance to Crizotinib
Berger L, Janning M, Velthaus J, Ben-Batalla I, Schatz S, Falk M, Iglauer P, Simon R, Cao R, Forcato C, Manaresi N, Bramlett K, Buson G, Hanssen A, Tiemann M, Sauter G, Bokemeyer C, Riethdorf S, Reck M, Pantel K, Wikman H, Loges S
J THORAC ONCOL. 2018;13(12):e243-e246.

Stromal Caveolin-1 and Caveolin-2 Expression in Primary Tumors and Lymph Node Metastases
Gerstenberger W, Wrage M, Kettunen E, Pantel K, Anttila S, Steurer S, Wikman H
ANAL CELL PATHOL. 2018;2018:8651790.

Frequency of Circulating Tumor Cells (CTC) in Patients with Brain Metastases: Implications as a Risk Assessment Marker in Oligo-Metastatic Disease
Hanssen A, Riebensahm C, Mohme M, Joosse S, Velthaus J, Berger L, Bernreuther C, Glatzel M, Loges S, Lamszus K, Westphal M, Riethdorf S, Pantel K, Wikman H
CANCERS. 2018;10(12):E527.

Chromosomal Aberrations Associated with Sequential Steps of the Metastatic Cascade in Colorectal Cancer Patients
Joosse S, Souche F, Babayan A, Gasch C, Kerkhoven R, Ramos J, Fabre J, Riethdorf S, König A, Wikman H, Alix-Panabières C, Pantel K
CLIN CHEM. 2018;64(10):1505-1512.

Clinical relevance of cytoskeleton associated proteins for ovarian cancer
Schiewek J, Schumacher U, Lange T, Joosse S, Wikman H, Pantel K, Mikhaylova M, Kneussel M, Linder S, Schmalfeldt B, Oliveira-Ferrer L, Windhorst S
J CANCER RES CLIN. 2018;144(11):2195-2205.

Comparative study of whole genome amplification and next generation sequencing performance of single cancer cells
Babayan A, Alawi M, Gormley M, Müller V, Wikman H, McMullin R, Smirnov D, Li W, Geffken M, Pantel K, Joosse S
ONCOTARGET. 2017;8(34):56066-56080.

Strong fascin expression promotes metastasis independent of its F-actin bundling activity
Heinz L, Muhs S, Schiewek J, Grüb S, Nalaskowski M, Lin Y, Wikman H, Oliveira-Ferrer L, Lange T, Wellbrock J, Konietzny A, Mikhaylova M, Windhorst S
ONCOTARGET. 2017;8(66):110077-110091.

PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression
Hohensee I, Chuang H, Grottke A, Werner S, Schulte A, Horn S, Lamszus K, Bartkowiak K, Witzel I, Westphal M, Matschke J, Glatzel M, Jücker M, Pukrop T, Pantel K, Wikman H
ONCOTARGET. 2017;8(4):6155-6168.

PLA2G7 associates with hormone receptor negativity in clinical breast cancer samples and regulates epithelial-mesenchymal transition in cultured breast cancer cells
Lehtinen L, Vainio P, Wikman H, Huhtala H, Mueller V, Kallioniemi A, Pantel K, Kronqvist P, Kallioniemi O, Carpèn O, Iljin K
J PATHOL CLIN RES. 2017;3(2):123-138.

Circulating Tumour Cell Release after Cement Augmentation of Vertebral Metastases
Mohme M, Riethdorf S, Dreimann M, Werner S, Maire C, Joosse S, Bludau F, Mueller V, Neves R, Stoecklein N, Lamszus K, Westphal M, Pantel K, Wikman H, Eicker S
SCI REP-UK. 2017;7(1):7196.

Biology and clinical significance of circulating tumor cell subpopulations in lung cancer
O'Flaherty L, Wikman H, Pantel K
TRANSL LUNG CANCER R. 2017;6(4):431-443.

Nanoplatforms for Circulating Tumor Cell Detection in Lung Cancer
Wikman H, Pantel K
CLIN CHEM. 2017;63(8):1318-1320.

Role of HYAL1 expression in primary breast cancer in the formation of brain metastases
Witzel I, Marx A, Müller V, Wikman H, Matschke J, Schumacher U, Stürken C, Prehm P, Laakmann E, Schmalfeldt B, Milde-Langosch K, Oliveira-Ferrer L
BREAST CANCER RES TR. 2017;162(3):427-438.

Potential Involvement of Jagged1 in Metastatic Progression of Human Breast Carcinomas
Bednarz-Knoll N, Efstathiou A, Gotzhein F, Wikman H, Mueller V, Kang Y, Pantel K
CLIN CHEM. 2016;62(2):378-386.

Enumeration and molecular characterization of tumor cells in lung cancer patients using a novel in vivo device for capturing circulating tumor cells
Gorges T, Penkalla N, Schalk T, Joosse S, Riethdorf S, Tucholski J, Lucke K, Wikman H, Jackson S, Brychter N, von Ahsen O, Schumann C, Krahn T, Pantel K
CLIN CANCER RES. 2016;22(9):2197-206.

Characterization of different CTC subpopulations in non-small cell lung cancer
Hanssen A, Wagner J, Gorges T, Tänzer A, Uzunoglu F, Driemel C, Stoecklein N, Knoefel W, Angenendt S, Hauch S, Atanackovic D, Loges S, Riethdorf S, Pantel K, Wikman H
SCI REP-UK. 2016;6:28010.

A novel microfluidic platform for size and deformability based separation and the subsequent molecular characterization of viable circulating tumor cells
Hvichia G, Parveen Z, Wagner C, Janning M, Quidde J, Stein A, Müller V, Loges S, Neves R, Stoecklein N, Wikman H, Riethdorf S, Pantel K, Gorges T
INT J CANCER. 2016;138(12):2894-904.

Breast cancer brain metastases:biology and new clinical perspectives
Witzel I, Oliveira-Ferrer L, Pantel K, Müller V, Wikman H
BREAST CANCER RES. 2016;18(1):8.

Disseminated Tumor Cells Persist in the Bone Marrow of Breast Cancer Patients through Sustained Activation of the Unfolded Protein Response
Bartkowiak K, Kwiatkowski M, Buck F, Gorges T, Nilse L, Assmann V, Andreas A, Müller V, Wikman H, Riethdorf S, Schlüter H, Pantel K
CANCER RES. 2015;75(24):5367-77.

Stromal expression of ALDH1 in human breast carcinomas indicates reduced tumor progression
Bednarz-Knoll N, Nastały P, Żaczek A, Stoupiec M, Riethdorf S, Wikman-Kocher H, Müller V, Skokowski J, Szade J, Sejda A, Wełnicka-Jaśkiewicz M, Pantel K
ONCOTARGET. 2015;6(29):26789-803.

Detection of Circulating Tumor Cells in Non-Small Cell Lung Cancer
Hanssen A, Loges S, Pantel K, Wikman-Kocher H
FRONT ONCOL. 2015;5:Art. 207.

Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases
Harter P, Bernatz S, Scholz A, Zeiner P, Zinke J, Kiyose M, Blasel S, Beschorner R, Senft C, Bender B, Ronellenfitsch M, Wikman-Kocher H, Glatzel M, Meinhardt M, Juratli T, Steinbach J, Plate K, Wischhusen J, Weide B, Mittelbronn M
ONCOTARGET. 2015;6(38):40836-40849.

Relevance of βGal-βGalNAc-containing glycans and the enzymes involved in their synthesis for invasion and survival in breast cancer patients
Milde-Langosch K, Schütze D, Oliveira-Ferrer L, Wikman-Kocher H, Müller V, Lebok P, Pantel K, Schröder C, Witzel I, Schumacher U
BREAST CANCER RES TR. 2015;151(3):515-28.

Suppression of early hematogenous dissemination of human breast cancer cells to bone marrow by retinoic acid induced 2
Werner S, Brors B, Eick J, Marques E, Pogenberg V, Parret A, Kemming D, Wood A, Edgren H, Neubauer H, Streichert T, Riethdorf S, Bedi U, Baccelli I, Jücker M, Eils R, Fehm T, Trumpp A, Johnsen S, Klefstrom J, Wilmanns M, Müller V, Pantel K, Wikman-Kocher H
CANCER DISCOV. 2015;5(5):506-19.

Iroquois homeobox 2 suppresses cellular motility and chemokine expression in breast cancer cells
Werner S, Stamm H, Pandjaitan M, Kemming D, Brors B, Pantel K, Wikman H
BMC CANCER. 2015;15(1):896.

Identification of HERC5 and its potential role in NSCLC progression
Wrage M, Hagmann W, Kemming D, Uzunoglu F, Riethdorf S, Harms-Effenberger K, Westphal M, Lamszus K, Kim S, Becker N, Izbicki J, Sandoval J, Esteller M, Pantel K, Risch A, Wikman-Kocher H
INT J CANCER. 2015;136(10):2264-72.

Increased serum levels of circulating exosomal microRNA-373 in receptor-negative breast cancer patients
Eichelser C, Stückrath I, Müller V, Milde-Langosch K, Wikman-Kocher H, Pantel K, Schwarzenbach H
ONCOTARGET. 2014;5(20):9650-63.

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis
LeBleu V, O'Connell J, Gonzalez Herrera K, Wikman-Kocher H, Pantel K, Haigis M, de Carvalho F, Damascena A, Domingos Chinen L, Rocha R, Asara J, Kalluri R
NAT CELL BIOL. 2014;16(10):992-1003.

Loss of 4q21.23-22.1 is a Prognostic Marker for Disease Free and Overall Survival in Non-Small Cell Lung Cancer
Uzunoglu F, Dethlefsen E, Hanssen A, Wrage M, Deutsch L, Harms-Effenberger K, Vashist Y, Reeh M, Sauter G, Simon R, Bockhorn M, Pantel K, Izbicki J, Wikman-Kocher H
PLOS ONE. 2014;9(12):e113315.

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients
Wikman-Kocher H, Westphal L, Schmid F, Pollari S, Kropidlowski J, Sielaff-Frimpong B, Glatzel M, Matschke J, Westphal M, Iljin K, Huhtala H, Terracciano L, Kallioniemi A, Sauter G, Müller V, Witzel I, Lamszus K, Kemming D, Pantel K
ONCOTARGET. 2014;5(10):3076-3087.

Frequent genetic alterations in EGFR- and HER2-driven pathways in breast cancer brain metastases
Hohensee I, Lamszus K, Riethdorf S, Meyer-Staeckling S, Glatzel M, Matschke J, Witzel I, Westphal M, Brandt B, Müller V, Pantel K, Wikman H
AM J PATHOL. 2013;183(1):83-95.

Accumulation of genomic alterations in 2p16, 9q33.1 and 19p13 in lung tumours of asbestos-exposed patients
Nymark P, Aavikko M, Mäkilä J, Ruosaari S, Hienonen-Kempas T, Wikman H, Salmenkivi K, Pirinen R, Karjalainen A, Vanhala E, Kuosma E, Anttila S, Kettunen E
MOL ONCOL. 2013;7(1):29-40.

VEGFR-2, CXCR-2 and PAR-1 germline polymorphisms as predictors of survival in pancreatic carcinoma
Uzunoglu F, Kolbe J, Wikman H, Güngör C, Bohn B, Nentwich M, Reeh M, König A, Bockhorn M, Kutup A, Mann O, Izbicki J, Vashist Y
ANN ONCOL. 2013;24(5):1282-90.

C-X-C motif receptor 2, endostatin and proteinase-activated receptor 1 polymorphisms as prognostic factors in NSCLC
Uzunoglu F, Yavari N, Bohn B, Nentwich M, Reeh M, Pantel K, Perez D, Tsui T, Bockhorn M, Mann O, Izbicki J, Wikman H, Vashist Y
LUNG CANCER. 2013;81(1):123-9.

Opposite roles of FOXA1 and NKX2-1 in lung cancer progression.
Deutsch L, Wrage M, Koops S, Glatzel M, Uzunoglu F, Kutup A, Hinsch A, Sauter G, Izbicki J, Pantel K, Wikman H
GENE CHROMOSOME CANC. 2012;51(6):618-629.

15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells.
Lehtinen L, Vainio P, Wikman H, Reemts J, Hilvo M, Issa R, Pollari S, Brandt B, Oresic M, Pantel K, Kallioniemi O, Iljin K
J PATHOL. 2012;226(4):674-686.

Circulating tumor-derived biomarkers in lung cancer.
Tänzer A, Alix-Panabières C, Wikman H, Pantel K
J THORAC DIS. 2012;4(5):448-449.

Vascular endothelial growth factor receptor 2 gene polymorphisms as predictors for tumor recurrence and overall survival in non-small-cell lung cancer.
Uzunoglu F, Kaufmann C, Wikman H, Güngör C, Bohn B, Nentwich M, Reeh M, Pantel K, Bockhorn M, Kutup A, Mann O, Izbicki J, Vashist Y
ANN SURG ONCOL. 2012;19(7):2159-2168.

Relevance of PTEN loss in brain metastasis formation in breast cancer patients.
Wikman H, Lamszus K, Detels N, Uslar L, Wrage M, Benner C, Hohensee I, Ylstra B, Eylmann K, Zapatka M, Sauter G, Kemming D, Glatzel M, Müller V, Westphal M, Pantel K
BREAST CANCER RES. 2012;14(2):49.

Clinical relevance of loss of 11p15 in primary and metastatic breast cancer: association with loss of PRKCDBP expression in brain metastases.
Wikman H, Sielaff-Frimpong B, Kropidlowski J, Witzel I, Milde-Langosch K, Sauter G, Westphal M, Lamszus K, Pantel K
PLOS ONE. 2012;7(10):47537.

Biologic role of activated leukocyte cell adhesion molecule overexpression in breast cancer cell lines and clinical tumor tissue.
Hein S, Müller V, Köhler N, Wikman H, Krenkel S, Streichert T, Schweizer M, Riethdorf S, Assmann V, Henningsen M, Beck K, Issa R, Jänicke F, Pantel K, Milde-Langosch K
BREAST CANCER RES TR. 2011;129(2):347-360.

Meta- and pooled analysis of GSTP1 polymorphism and lung cancer: a HuGE-GSEC review.
Cote M, Chen W, Smith D, Benhamou S, Bouchardy C, Butkiewicz D, Fong K, Gené M, Hirvonen A, Kiyohara C, Larsen J, Lin P, Raaschou-Nielsen O, Povey A, Reszka E, Risch A, Schneider J, Schwartz A, Sorensen M, Figueras J, Tokudome S, Pu Y, Yang P, Wenzlaff A, Wikman H, Taioli E
AM J EPIDEMIOL. 2009;169(7):802-814.

DNA copy number loss and allelic imbalance at 2p16 in lung cancer associated with asbestos exposure.
Kettunen E, Aavikko M, Nymark P, Ruosaari S, Wikman H, Vanhala E, Salmenkivi K, Pirinen R, Karjalainen A, Kuosma E, Anttila S
BRIT J CANCER. 2009;100(8):1336-1342.

Molecular alterations at 9q33.1 and polyploidy in asbestos-related lung cancer.
Nymark P, Kettunen E, Aavikko M, Ruosaari S, Kuosma E, Vanhala E, Salmenkivi K, Pirinen R, Karjalainen A, Knuutila S, Wikman H, Anttila S
CLIN CANCER RES. 2009;15(2):468-475.

Genomic profiles associated with early micrometastasis in lung cancer: relevance of 4q deletion.
Wrage M, Ruosaari S, Eijk P, Kaifi J, Hollmén J, Yekebas E, Izbicki J, Brakenhoff R, Streichert T, Riethdorf S, Glatzel M, Ylstra B, Pantel K, Wikman H
CLIN CANCER RES. 2009;15(5):1566-1574.

Molecular and genetic changes in asbestos-related lung cancer.
Nymark P, Wikman H, Hienonen-Kempas T, Anttila S
CANCER LETT. 2008;265(1):1-15.

Review: Biological relevance of disseminated tumor cells in cancer patients.
Riethdorf S, Wikman H, Pantel K
INT J CANCER. 2008;123(9):1991-2006.

Pathways affected by asbestos exposure in normal and tumour tissue of lung cancer patients.
Ruosaari S, Hienonen-Kempas T, Puustinen A, Sarhadi V, Hollmén J, Knuutila S, Saharinen J, Wikman H, Anttila S
BMC MED GENOMICS. 2008;1:55.

Cancer micrometastasis and tumour dormancy.
Wikman H, Vessella R, Pantel K
APMIS. 2008;116(7-8):754-770.

Gene expression and copy number profiling suggests the importance of allelic imbalance in 19p in asbestos-associated lung cancer.
Wikman H, Ruosaari S, Nymark P, Sarhadi V, Saharinen J, Vanhala E, Karjalainen A, Hollmén J, Knuutila S, Anttila S
ONCOGENE. 2007;26(32):4730-4737.

Letzte Aktualisierung aus dem FIS: 23.12.2024 - 23:36 Uhr