2024

The ST2+ Treg/amphiregulin axis protects from immune-mediated hepatitis
Wachtendorf S, Fitriasari J, Ochel A, Heinrich F, Westendorf A, Tiegs G, Neumann K
FRONT IMMUNOL. 2024;15:1351405.

2023

Transcriptional and Clonal Characterization of Cytotoxic T Cells in Crescentic Glomerulonephritis
Mueller A, Zhao Y, Cicek H, Paust H, Sivayoganathan A, Linke A, Wegscheid C, Wiech T, Huber T, Meyer-Schwesinger C, Bonn S, Prinz I, Panzer U, Tiegs G, Krebs C, Neumann K
J AM SOC NEPHROL. 2023;34(6):1003-1018.

2022

Antigen Cross-Presentation by Murine Proximal Tubular Epithelial Cells Induces Cytotoxic and Inflammatory CD8+ T Cells
Linke A, Cicek H, Müller A, Meyer-Schwesinger C, Melderis S, Wiech T, Wegscheid C, Ridder J, Steinmetz O, Diehl L, Tiegs G, Neumann K
CELLS-BASEL. 2022;11(9):.

The Amphiregulin/EGFR axis protects from lupus nephritis via downregulation of pathogenic CD4+ T helper cell responses
Melderis S, Warkotsch M, Dang J, Hagenstein J, Ehnold L, Herrnstadt G, Niehus C, Feindt F, Kylies D, Puelles V, Berasain C, Avila M, Neumann K, Tiegs G, Huber T, Tharaux P, Steinmetz O
J AUTOIMMUN. 2022;129:.

Conventional NK Cells and Type 1 Innate Lymphoid Cells Do Not Influence Pathogenesis of Experimental Glomerulonephritis
Rickassel C, Gnirck A, Shaikh N, Adamiak V, Waterhölter A, Tanriver Y, Neumann K, Huber T, Gasteiger G, Panzer U, Turner J
J IMMUNOL. 2022;208(7):1585-1594.

2021

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)
Cossarizza A, Chang H, Radbruch A, Abrignani S, Addo R, Akdis M, Andrä I, Andreata F, Annunziato F, Arranz E, Bacher P, Bari S, Barnaba V, Barros-Martins J, Baumjohann D, Beccaria C, Bernardo D, Boardman D, Borger J, Böttcher C, Brockmann L, Burns M, Busch D, Cameron G, Cammarata I, Cassotta A, Chang Y, Chirdo F, Christakou E, Čičin-Šain L, Cook L, Corbett A, Cornelis R, Cosmi L, Davey M, De Biasi S, De Simone G, Del Zotto G, Delacher M, Di Rosa F, Santo J, Diefenbach A, Dong J, Dörner T, Dress R, Dutertre C, Eckle S, Eede P, Evrard M, Falk C, Feuerer M, Fillatreau S, Fiz-Lopez A, Follo M, Foulds G, Fröbel J, Gagliani N, Galletti G, Gangaev A, Garbi N, Garrote J, Geginat J, Gherardin N, Gibellini L, Ginhoux F, Godfrey D, Gruarin P, Haftmann C, Hansmann L, Harpur C, Hayday A, Heine G, Hernández D, Herrmann M, Hoelsken O, Huang Q, Huber S, Huber J, Huehn J, Hundemer M, Hwang W, Iannacone M, Ivison S, Jäck H, Jani P, Keller B, Kessler N, Ketelaars S, Knop L, Knopf J, Koay H, Kobow K, Kriegsmann K, Kristyanto H, Krueger A, Kuehne J, Kunze-Schumacher H, Kvistborg P, Kwok I, Latorre D, Lenz D, Levings M, Lino A, Liotta F, Long H, Lugli E, MacDonald K, Maggi L, Maini M, Mair F, Manta C, Manz R, Mashreghi M, Mazzoni A, McCluskey J, Mei H, Melchers F, Melzer S, Mielenz D, Monin L, Moretta L, Multhoff G, Muñoz L, Muñoz-Ruiz M, Muscate F, Natalini A, Neumann K, Ng L, Niedobitek A, Niemz J, Almeida L, Notarbartolo S, Ostendorf L, Pallett L, Patel A, Percin G, Peruzzi G, Pinti M, Pockley A, Pracht K, Prinz I, Pujol-Autonell I, Pulvirenti N, Quatrini L, Quinn K, Radbruch H, Rhys H, Rodrigo M, Romagnani C, Saggau C, Sakaguchi S, Sallusto F, Sanderink L, Sandrock I, Schauer C, Scheffold A, Scherer H, Schiemann M, Schildberg F, Schober K, Schoen J, Schuh W, Schüler T, Schulz A, Schulz S, Schulze J, Simonetti S, Singh J, Sitnik K, Stark R, Starossom S, Stehle C, Szelinski F, Tan L, Tarnok A, Tornack J, Tree T, van Beek J, van de Veen W, van Gisbergen K, Vasco C, Verheyden N, von Borstel A, Ward-Hartstonge K, Warnatz K, Waskow C, Wiedemann A, Wilharm A, Wing J, Wirz O, Wittner J, Yang J, Yang J
EUR J IMMUNOL. 2021;51(12):2708-3145.

Antigen presentation, autoantibody production, and therapeutic targets in autoimmune liver disease
Horst A, Kumashie K, Neumann K, Diehl L, Tiegs G
CELL MOL IMMUNOL. 2021;18(1):92-111.

Immune regulation in renal inflammation
Neumann K, Tiegs G
CELL TISSUE RES. 2021;385(2):305-322.

2020

Glioma escape signature and clonal development under immune pressure
Maire C, Mohme M, Bockmayr M, Fita K, Riecken K, Börnigen D, Alawi M, Failla A, Kolbe K, Zapf S, Holz M, Neumann K, Dührsen L, Lange T, Fehse B, Westphal M, Lamszus K
J CLIN INVEST. 2020;130(10):5257-5271.

Amphiregulin Aggravates Glomerulonephritis via Recruitment and Activation of Myeloid Cells
Melderis S, Hagenstein J, Warkotsch M, Dang J, Herrnstadt G, Niehus C, Neumann K, Panzer U, Berasain C, Avila M, Tharaux P, Tiegs G, Steinmetz O
J AM SOC NEPHROL. 2020;31(9):1996-2012.

Hepatic ILC2 activity is regulated by liver inflammation-induced cytokines and effector CD4+ T cells
Steinmann S, Schoedsack M, Heinrich F, Breda P, Ochel A, Tiegs G, Neumann K
SCI REP-UK. 2020;10(1):1071.

2019

Deletion of tumour necrosis factor α receptor 1 elicits an increased TH17 immune response in the chronically inflamed liver
Berkhout L, Barikbin R, Schiller B, Ravichandran G, Krech T, Neumann K, Sass G, Tiegs G
SCI REP-UK. 2019;9(1):4232.

Renal proximal tubular epithelial cells exert immunomodulatory function by driving inflammatory CD4+ T cell responses
Breda P, Wiech T, Meyer-Schwesinger C, Grahammer F, Huber T, Panzer U, Tiegs G, Neumann K
AM J PHYSIOL-RENAL. 2019;317(1):F77-F89.

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)
Cossarizza A, Chang H, Radbruch A, Acs A, Adam D, Adam-Klages S, Agace W, Aghaeepour N, Akdis M, Allez M, Almeida L, Alvisi G, Anderson G, Andrä I, Annunziato F, Anselmo A, Bacher P, Baldari C, Bari S, Barnaba V, Barros-Martins J, Battistini L, Bauer W, Baumgart S, Baumgarth N, Baumjohann D, Baying B, Bebawy M, Becher B, Beisker W, Benes V, Beyaert R, Blanco A, Boardman D, Bogdan C, Borger J, Borsellino G, Boulais P, Bradford J, Brenner D, Brinkman R, Brooks A, Busch D, Büscher M, Bushnell T, Calzetti F, Cameron G, Cammarata I, Cao X, Cardell S, Casola S, Cassatella M, Cavani A, Celada A, Chatenoud L, Chattopadhyay P, Chow S, Christakou E, Čičin-Šain L, Clerici M, Colombo F, Cook L, Cooke A, Cooper A, Corbett A, Cosma A, Cosmi L, Coulie P, Cumano A, Cvetkovic L, Dang V, Dang-Heine C, Davey M, Davies D, De Biasi S, Del Zotto G, Dela Cruz G, Delacher M, Della Bella S, Dellabona P, Deniz G, Dessing M, Di Santo J, Diefenbach A, Dieli F, Dolf A, Dörner T, Dress R, Dudziak D, Dustin M, Dutertre C, Ebner F, Eckle S, Edinger M, Eede P, Ehrhardt G, Eich M, Engel P, Engelhardt B, Erdei A, Esser C, Everts B, Evrard M, Falk C, Fehniger T, Felipo-Benavent M, Ferry H, Feuerer M, Filby A, Filkor K, Fillatreau S, Follo M, Förster I, Foster J, Foulds G, Frehse B, Frenette P, Frischbutter S, Fritzsche W, Galbraith D, Gangaev A, Garbi N, Gaudilliere B, Gazzinelli R, Geginat J, Gerner W, Gherardin N, Ghoreschi K, Gibellini L, Ginhoux F, Goda K, Godfrey D, Goettlinger C, González-Navajas J, Goodyear C, Gori A, Grogan J, Grummitt D, Grützkau A, Haftmann C, Hahn J, Hammad H, Hämmerling G, Hansmann L, Hansson G, Harpur C, Hartmann S, Hauser A, Hauser A, Haviland D, Hedley D, Hernández D, Herrera G, Herrmann M, Hess C, Höfer T, Hoffmann P, Hogquist K, Holland T, Höllt T, Holmdahl R, Hombrink P, Houston J, Hoyer B, Huang B, Huang F, Huber J, Huehn J, Hundemer M, Hunter C, Hwang W, Iannone A, Ingelfinger F, Ivison S, Jäck H, Jani P, Jávega B, Jonjic S, Kaiser T, Kalina T, Kamradt T, Kaufmann S, Keller B, Ketelaars S, Khalilnezhad A, Khan S, Kisielow J, Klenerman P, Knopf J, Koay H, Kobow K, Kolls J, Kong W, Kopf M, Korn T, Kriegsmann K, Kristyanto H, Kroneis T, Krueger A, Kühne J, Kukat C, Kunkel D, Kunze-Schumacher H, Kurosaki T, Kurts C, Kvistborg P, Kwok I, Landry J, Lantz O, Lanuti P, LaRosa F, Lehuen A, LeibundGut-Landmann S, Leipold M, Leung L, Levings M, Lino A, Liotta F, Litwin V, Liu Y, Ljunggren H, Lohoff M, Lombardi G, Lopez L, López-Botet M, Lovett-Racke A, Lubberts E, Luche H, Ludewig B, Lugli E, Lunemann S, Maecker H, Maggi L, Maguire O, Mair F, Mair K, Mantovani A, Manz R, Marshall A, Martínez-Romero A, Martrus G, Marventano I, Maslinski W, Matarese G, Mattioli A, Maueröder C, Mazzoni A, McCluskey J, McGrath M, McGuire H, McInnes I, Mei H, Melchers F, Melzer S, Mielenz D, Miller S, Mills K, Minderman H, Mjösberg J, Moore J, Moran B, Moretta L, Mosmann T, Müller S, Multhoff G, Muñoz L, Münz C, Nakayama T, Nasi M, Neumann K, Ng L, Niedobitek A, Nourshargh S, Núñez G, O'Connor J, Ochel A, Oja A, Ordonez D, Orfao A, Orlowski-Oliver E, Ouyang W, Oxenius A, Palankar R, Panse I, Pattanapanyasat K, Paulsen M, Pavlinic D, Penter L, Peterson P, Peth C, Petriz J, Piancone F, Pickl W, Piconese S, Pinti M, Pockley A, Podolska M, Poon Z, Pracht K, Prinz I, Pucillo C, Quataert S, Quatrini L, Quinn K, Radbruch H, Radstake T, Rahmig S, Rahn H, Rajwa B, Ravichandran G, Raz Y, Rebhahn J, Recktenwald D, Reimer D, Reis E Sousa C, Remmerswaal E, Richter L, Rico L, Riddell A, Rieger A, Robinson J, Romagnani C, Rubartelli A, Ruland J, Saalmüller A, Saeys Y, Saito T, Sakaguchi S, Sala-de-Oyanguren F, Samstag Y, Sanderson S, Sandrock I, Santoni A, Sanz R, Saresella M, Sautes-Fridman C, Sawitzki B, Schadt L, Scheffold A, Scherer H, Schiemann M, Schildberg F, Schimisky E, Schlitzer A, Schlosser J, Schmid S, Schmitt S, Schober K, Schraivogel D, Schuh W, Schüler T, Schulte R, Schulz A, Schulz S, Scottá C, Scott-Algara D, Sester D, Shankey T, Silva-Santos B, Simon A, Sitnik K, Sozzani S, Speiser D, Spidlen J, Stahlberg A, Stall A, Stanley N, Stark R, Stehle C, Steinmetz T, Stockinger H, Takahama Y, Takeda K, Tan L, Tárnok A, Tiegs G, Toldi G, Tornack J, Traggiai E, Trebak M, Tree T, Trotter J, Trowsdale J, Tsoumakidou M, Ulrich H, Urbanczyk S, van de Veen W, van den Broek M, van der Pol E, Van Gassen S, Van Isterdael G, van Lier R, Veldhoen M, Vento-Asturias S, Vieira P, Voehringer D, Volk H, von Borstel A, von Volkmann K, Waisman A, Walker R, Wallace P, Wang S, Wang X, Ward M, Ward-Hartstonge K, Warnatz K, Warnes G, Warth S, Waskow C, Watson J, Watzl C, Wegener L, Weisenburger T, Wiedemann A, Wienands J, Wilharm A, Wilkinson R, Willimsky G, Wing J, Winkelmann R, Winkler T, Wirz O, Wong A, Wurst P, Yang J, Yang J, Yazdanbakhsh M, Yu L, Yue A, Zhang H, Zhao Y, Ziegler S, Zielinski C, Zimmermann J, Zychlinsky A
EUR J IMMUNOL. 2019;49(10):1457-1973.

The co-inhibitory molecule PD-L1 contributes to regulatory T cell-mediated protection in murine crescentic glomerulonephritis
Neumann K, Ostmann A, Breda P, Ochel A, Tacke F, Paust H, Panzer U, Tiegs G
SCI REP-UK. 2019;9:2038.

Type 2 Innate Lymphoid Cells in Liver and Gut: From Current Knowledge to Future Perspectives
Ochel A, Tiegs G, Neumann K
INT J MOL SCI. 2019;20(8):.

Interferon-γ-dependent immune responses contribute to the pathogenesis of sclerosing cholangitis in mice
Ravichandran G, Neumann K, Berkhout L, Weidemann S, Langeneckert A, Schwinge D, Poch T, Huber S, Schiller B, Hess L, Ziegler A, Oldhafer K, Barikbin R, Schramm C, Altfeld M, Tiegs G
J HEPATOL. 2019;71(4):773-782.

2018

Carcinoembryonic antigen-related cell adhesion molecule 1 controls IL-2-dependent regulatory T-cell induction in immune-mediated hepatitis in mice
Horst A, Wegscheid C, Schaefers C, Schiller B, Neumann K, Lunemann S, Langeneckert A, Oldhafer K, Weiler-Normann C, Lang K, Singer B, Altfeld M, Diehl L, Tiegs G
HEPATOLOGY. 2018;68(1):200-214.

NLRP3 Inflammasome and IL-33: Novel Players in Sterile Liver Inflammation
Neumann K, Schiller B, Tiegs G
INT J MOL SCI. 2018;19(9):2732.

2017

A Proinflammatory Role of Type 2 Innate Lymphoid Cells in Murine Immune-Mediated Hepatitis
Neumann K, Karimi K, Meiners J, Voetlause R, Steinmann S, Dammermann W, Lüth S, Asghari F, Wegscheid C, Horst A, Tiegs G
J IMMUNOL. 2017;198(1):128-137.

2016

Modulation of liver tolerance by conventional and nonconventional antigen-presenting cells and regulatory immune cells
Horst A, Neumann K, Diehl L, Tiegs G
CELL MOL IMMUNOL. 2016;13(3):277-292.

2015

Chemokine Transfer by Liver Sinusoidal Endothelial Cells Contributes to the Recruitment of CD4+ T Cells into the Murine Liver
Neumann K, Erben U, Kruse N, Wechsung K, Schumann M, Klugewitz K, Scheffold A, Kühl A
PLOS ONE. 2015;10(6):Art. e0123867.

Liver sinusoidal endothelial cells induce immunosuppressive IL-10-producing Th1 cells via the Notch pathway
Neumann K, Rudolph C, Neumann C, Janke M, Amsen D, Scheffold A
EUR J IMMUNOL. 2015;45(7):2008-16.

2014

Role of Blimp-1 in programing Th effector cells into IL-10 producers
Neumann C, Heinrich F, Neumann K, Junghans V, Mashreghi M, Ahlers J, Janke M, Rudolph C, Mockel-Tenbrinck N, Kühl A, Heimesaat M, Esser C, Im S, Radbruch A, Rutz S, Scheffold A
J EXP MED. 2014;211(9):1807-19.

2012

Connecting liver and gut: murine liver sinusoidal endothelium induces gut tropism of CD4+ T cells via retinoic acid
Neumann K, Kruse N, Szilagyi B, Erben U, Rudolph C, Flach A, Zeitz M, Hamann A, Klugewitz K
HEPATOLOGY. 2012;55(6):1976-84.

2011

Accumulation and local proliferation of antigen-specific CD4+ T cells in antigen-bearing tissue
Doebis C, Menning A, Neumann K, Ghani S, Schlawe K, Lauer U, Hamann A, Huehn J, Syrbe U
IMMUNOL CELL BIOL. 2011;89(4):566-72.

2009

Priming of CD4+ T cells by liver sinusoidal endothelial cells induces CD25low forkhead box protein 3- regulatory T cells suppressing autoimmune hepatitis
Kruse N, Neumann K, Schrage A, Derkow K, Schott E, Erben U, Kühl A, Loddenkemper C, Zeitz M, Hamann A, Klugewitz K
HEPATOLOGY. 2009;50(6):1904-13.

2008

Enhanced T cell transmigration across the murine liver sinusoidal endothelium is mediated by transcytosis and surface presentation of chemokines
Schrage A, Wechsung K, Neumann K, Schumann M, Schulzke J, Engelhardt B, Zeitz M, Hamann A, Klugewitz K
HEPATOLOGY. 2008;48(4):1262-72.

Letzte Aktualisierung aus dem FIS: 23.12.2024 - 23:35 Uhr