Miniproteins may have a big impact: new therapeutics for autoimmune diseases and beyond
Asada N, Krebs C, Panzer U
SIGNAL TRANSDUCT TAR. 2024;9(1):298.

Deficiency of Complement C3a and C5a receptors Does Not Prevent Angiotensin II-Induced Hypertension and Hypertensive End-Organ Damage
Bode M, Herrnstadt G, Dreher L, Ehnert N, Kirkerup P, Lindenmeyer M, Meyer-Schwesinger C, Ehmke H, Köhl J, Huber T, Krebs C, Steinmetz O, Wiech T, Wenzel U
HYPERTENSION. 2024;81(1):138-150.

Immune profiling-based targeting of pathogenic T cells with ustekinumab in ANCA-associated glomerulonephritis
Engesser J, Khatri R, Schaub D, Zhao Y, Paust H, Sultana Z, Asada N, Riedel J, Sivayoganathan V, Peters A, Kaffke A, Jauch-Speer S, Goldbeck-Strieder T, Puelles V, Wenzel U, Steinmetz O, Hoxha E, Turner J, Mittrücker H, Wiech T, Huber T, Bonn S, Krebs C, Panzer U
NAT COMMUN. 2024;15(1):8220.

Targeting T cell plasticity in kidney and gut inflammation by pooled single-cell CRISPR screening
Enk L, Hellmig M, Riecken K, Kilian C, Datlinger P, Jauch-Speer S, Neben T, Sultana Z, Sivayoganathan V, Borchers A, Paust H, Zhao Y, Asada N, Liu S, Agalioti T, Pelczar P, Wiech T, Bock C, Huber T, Huber S, Bonn S, Gagliani N, Fehse B, Panzer U, Krebs C
SCI IMMUNOL. 2024;9(96):eadd6774.

Apoptotic cell identity induces distinct functional responses to IL-4 in efferocytic macrophages
Liebold I, Al Jawazneh A, Casar C, Lanzloth C, Leyk S, Hamley M, Wong M, Kylies D, Gräfe S, Edenhofer I, Aranda-Pardos I, Kriwet M, Haas H, Krause J, Hadjilaou A, Schromm A, Richardt U, Eggert P, Tappe D, Weidemann S, Ghosh S, Krebs C, A-Gonzalez N, Worthmann A, Lohse A, Huber S, Rothlin C, Puelles V, Jacobs T, Gagliani N, Bosurgi L
SCIENCE. 2024;384(6691):eabo7027.

Diagnostic leukapheresis reveals distinct phenotypes of NSCLC circulating tumor cells
Rieckmann L, Spohn M, Ruff L, Agorku D, Becker L, Borchers A, Krause J, O'Reilly R, Hille J, Velthaus-Rusik J, Beumer N, Günther A, Willnow L, Imbusch C, Iglauer P, Simon R, Franzenburg S, Winter H, Thomas M, Bokemeyer C, Gagliani N, Krebs C, Sprick M, Hardt O, Riethdorf S, Trumpp A, Stoecklein N, Peine S, Rosenstiel P, Pantel K, Loges S, Janning M
MOL CANCER. 2024;23(1):93.

Targeting monocyte derived CCL17 attenuates murine crescentic glomerulonephritis by affecting renal CCR4+ regulatory T cell recruitment
Song N, Paust H, Asada N, Peters A, Kaffke A, Krebs C, Panzer U, Riedel J
AM J NEPHROL. 2024;55(2):214-224.

γδ T cells in immune-mediated kidney disease
Waterhölter A, Krebs C, Panzer U
EUR J IMMUNOL. 2024 [Epub ahead of print];e2451069.

Kidney-resident innate-like memory γδ T cells control chronic Staphylococcus aureus infection of mice
Bertram T, Reimers D, Lory N, Schmidt C, Schmid J, C Heinig L, Bradtke P, Rattay G, Zielinski S, Hellmig M, Bartsch P, Rohde H, Nuñez S, Rosemblatt M, Bono M, Gagliani N, Sandrock I, Panzer U, Krebs C, Meyer-Schwesinger C, Prinz I, Mittrücker H
P NATL ACAD SCI USA. 2023;120(1):e2210490120.

Mucosal-associated invariant T cells contribute to suppression of inflammatory myeloid cells in immune-mediated kidney disease
Gnirck A, Philipp M, Waterhölter A, Wunderlich M, Shaikh N, Adamiak V, Henneken L, Kautz T, Xiong T, Klaus D, Tomczyk P, Al-Bahra M, Menche D, Walkenhorst M, Lantz O, Willing A, Friese M, Huber T, Krebs C, Panzer U, Kurts C, Turner J
NAT COMMUN. 2023;14(1):.

Reduction of IFN-I responses by plasmacytoid dendritic cells in a longitudinal trans men cohort
Grünhagel B, Borggrewe M, Hagen S, Ziegler S, Henseling F, Glau L, Thiele R, Pujantell M, Sivayoganathan V, Padoan B, Claussen J, Düsedau A, Hennesen J, Bunders M, Bonn S, Tolosa E, Krebs C, Dorn C, Altfeld M
ISCIENCE. 2023;26(11):108209.

The CCR6/CCL20 Axis Expands RORγt+ Tregs to Protect from Glomerulonephritis
Herrnstadt G, Niehus C, Ramcke T, Hagenstein J, Ehnold L, Nosko A, Warkotsch M, Feindt F, Melderis S, Paust H, Sivayoganathan V, Jauch-Speer S, Wong M, Indenbirken D, Krebs C, Huber T, Panzer U, Puelles V, Kluger M, Steinmetz O
KIDNEY INT. 2023;104(1):74-89.

Single-cell transcriptomics reveals a mechanosensitive injury signaling pathway in early diabetic nephropathy
Liu S, Zhao Y, Lu S, Zhang T, Lindenmeyer M, Nair V, Gies S, Wu G, Nelson R, Czogalla J, Aypek H, Zielinski S, Liao Z, Schaper M, Fermin D, Cohen C, Delic D, Krebs C, Grahammer F, Wiech T, Kretzler M, Meyer-Schwesinger C, Bonn S, Huber T
GENOME MED. 2023;15(1):2.

Transcriptional and Clonal Characterization of Cytotoxic T Cells in Crescentic Glomerulonephritis
Mueller A, Zhao Y, Cicek H, Paust H, Sivayoganathan A, Linke A, Wegscheid C, Wiech T, Huber T, Meyer-Schwesinger C, Bonn S, Prinz I, Panzer U, Tiegs G, Krebs C, Neumann K
J AM SOC NEPHROL. 2023;34(6):1003-1018.

Kidney Biopsy Findings in Patients with SARS-CoV-2 Infection or after COVID-19 Vaccination
Noriega M, Husain-Syed F, Wulf S, Csala B, Krebs C, Jabs W, Zipfel P, Gröne H, Wiech T
CLIN J AM SOC NEPHRO. 2023;18(5):613-625.

CD4+ T cells produce GM-CSF and drive immune-mediated glomerular disease by licensing monocyte-derived cells to produce MMP12
Paust H, Song N, De Feo D, Asada N, Tuzlak S, Zhao Y, Riedel J, Hellmig M, Sivayoganathan A, Peters A, Kaffke A, Borchers A, Wenzel U, Steinmetz O, Tiegs G, Meister E, Mack M, Kurts C, von Vietinghoff S, Lindenmeyer M, Hoxha E, Stahl R, Huber T, Bonn S, Meyer-Schwesinger C, Wiech T, Turner J, Becher B, Krebs C, Panzer U
SCI TRANSL MED. 2023;15(687):.

Glucocorticoids target the CXCL9/CXCL10-CXCR3 axis and confer protection against immune-mediated kidney injury
Riedel J, Robben L, Paust H, Zhao Y, Asada N, Song N, Peters A, Kaffke A, Borchers A, Tiegs G, Seifert L, Tomas N, Hoxha E, Wenzel U, Huber T, Wiech T, Turner J, Krebs C, Panzer U
JCI INSIGHT. 2023;8(1):.

Retinoic acid drives intestine-specific adaptation of effector ILC2s originating from distant sites
Shaikh N, Waterhölter A, Gnirck A, Becker M, Adamiak V, Henneken L, Wunderlich M, Hartmann W, Linnemann L, Huber T, Krebs C, Panzer U, Locksley R, Wilhelm C, Breloer M, Turner J
J EXP MED. 2023;220(12):.

Tr1 Cells Emerge and Suppress Effector Th17 Cells in Glomerulonephritis
Soukou-Wargalla S, Kilian C, Velasquez L, Machicote A, Letz P, Tran H, Domanig S, Bertram F, Stumme F, Bedke T, Giannou A, Kempski J, Sabihi M, Song N, Paust H, Borchers A, Garcia Perez L, Pelczar P, Liu B, Ergen C, Steglich B, Muscate F, Huber T, Panzer U, Gagliani N, Krebs C, Huber S
J IMMUNOL. 2023;211(11):1669-1679.

Th17 cell plasticity towards a T-bet-dependent Th1 phenotype is required for bacterial control in Staphylococcus aureus infection
Bartsch P, Kilian C, Hellmig M, Paust H, Borchers A, Sivayoganathan A, Enk L, Zhao Y, Shaikh N, Büttner H, Wong M, Puelles V, Wiech T, Flavell R, Huber T, Turner J, Bonn S, Huber S, Gagliani N, Mittrücker H, Rohde H, Panzer U, Krebs C
PLOS PATHOG. 2022;18(4):e1010430.

An Interdisciplinary Diagnostic Approach to Guide Therapy in C3 Glomerulopathy
Schmidt T, Afonso S, Perie L, Heidenreich K, Wulf S, Krebs C, Zipfel P, Wiech T
FRONT IMMUNOL. 2022;13:.

An extracellular vesicle-related gene expression signature identifies high-risk patients in medulloblastoma
Albert T, Interlandi M, Sill M, Graf M, Moreno N, Menck K, Rohlmann A, Melcher V, Korbanka S, Meyer Zu Hörste G, Lautwein T, Frühwald M, Krebs C, Holdhof D, Schoof M, Bleckmann A, Missler M, Dugas M, Schüller U, Jäger N, Pfister S, Kerl K
NEURO-ONCOLOGY. 2021;23(4):586-598.

Tissue-specific therapy in immune-mediated kidney diseases: new ARGuments for targeting the IL-23/IL-17 axis
Krebs C, Turner J, Riedel J, Panzer U
J CLIN INVEST. 2021;131(12):.

Lack of Evidence for an Association between Previous HEV Genotype-3 Exposure and Glomerulonephritis in General
Pischke S, Tamanaei S, Mader M, Wiesch J, Petersen-Benz C, Haddad M, Addo M, Schmidt T, Huber T, Krebs C, Steinmetz O, Turner J, Hoxha E, Horvatits T
PATHOGENS. 2021;11(1):.

Single-cell atlas of hepatic T cells reveals expansion of liver-resident naive-like CD4+ T cells in primary sclerosing cholangitis
Poch T, Krause J, Casar C, Liwinski T, Glau L, Kaufmann M, Ahrenstorf A, Hess L, Ziegler A, Martrus G, Lunemann S, Sebode M, Li J, Schwinge D, Krebs C, Franke A, Friese M, Oldhafer K, Fischer L, Altfeld M, Lohse A, Huber S, Tolosa E, Gagliani N, Schramm C
J HEPATOL. 2021;75(2):414-423.

Kreatininanstieg, Fieber und Hämoptysen: „Double trouble“: „Double trouble“
Riedel J, Wiech T, Krebs C, Panzer U
NEPHROLOGE. 2021;16(6):386-390.

IL-17 receptor c signaling controls CD4⁺T_H17 immune responses and tissue injury in immune-mediated kidney diseases
Schmidt T, Luebbe J, Kilian C, Riedel J, Hiekmann S, Asada N, Ginsberg P, Robben L, Song N, Kaffke A, Peters A, Borchers A, Flavell R, Gagliani N, Pelzcar P, Huber S, Huber T, Turner J, Paust H, Krebs C, Panzer U
J AM SOC NEPHROL. 2021;32(12):3081-3098.

T cell plasticity in renal autoimmune disease
Soukou S, Huber S, Krebs C
CELL TISSUE RES. 2021;385(2):323-333.

Kidney organoid systems for studies of immune-mediated kidney diseases: challenges and opportunities
Stein M, Braun F, Krebs C, Bunders M
CELL TISSUE RES. 2021;385(2):457-473.

A fetal wave of human type 3 effector γδ cells with restricted TCR diversity persists into adulthood
Tan L, Fichtner A, Bruni E, Odak I, Sandrock I, Bubke A, Borchers A, Schultze-Florey C, Koenecke C, Förster R, Jarek M, von Kaisenberg C, Schulz A, Chu X, Zhang B, Li Y, Panzer U, Krebs C, Ravens S, Prinz I
SCI IMMUNOL. 2021;6(58):.

Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients
Zhao Y, Kilian C, Turner J, Bosurgi L, Roedl K, Bartsch P, Gnirck A, Cortesi F, Schultheiß C, Hellmig M, Enk L, Hausmann F, Borchers A, Wong M, Paust H, Siracusa F, Scheibel N, Herrmann M, Rosati E, Bacher P, Kylies D, Jarczak D, Lütgehetmann M, Pfefferle S, Steurer S, Zur Wiesch J, Puelles V, Sperhake J, Addo M, Lohse A, Binder M, Huber S, Huber T, Kluge S, Bonn S, Panzer U, Gagliani N, Krebs C
SCI IMMUNOL. 2021;6(56):.

Single-cell biology to decode the immune cellular composition of kidney inflammation.
Zhao Y, Panzer U, Bonn S, Krebs C
CELL TISSUE RES. 2021;385(2):435-443.

Deep learning-based molecular morphometrics for kidney biopsies
Zimmermann M, Klaus M, Wong M, Thebille A, Gernhold L, Kuppe C, Halder M, Kranz J, Wanner N, Braun F, Wulf S, Wiech T, Panzer U, Krebs C, Hoxha E, Kramann R, Huber T, Bonn S, Puelles V
JCI INSIGHT. 2021;6(7):e144779.

Pathogen-induced tissue-resident memory TH17 (TRM17) cells amplify autoimmune kidney disease
Krebs C, Reimers D, Zhao Y, Paust H, Bartsch P, Nuñez S, Rosemblatt M, Hellmig M, Kilian C, Borchers A, Enk L, Zinke M, Becker M, Schmid J, Klinge S, Wong M, Puelles V, Schmidt C, Bertram T, Stumpf N, Hoxha E, Meyer-Schwesinger C, Lindenmeyer M, Cohen C, Rink M, Kurts C, Franzenburg S, Koch-Nolte F, Turner J, Riedel J, Huber S, Gagliani N, Huber T, Wiech T, Rohde H, Bono M, Bonn S, Panzer U, Mittrücker H
SCI IMMUNOL. 2020;5(50):.

Drawing a single-cell landscape of the human kidney in (pseudo)-space and time
Krebs C, Schlitzer A, Kurts C
KIDNEY INT. 2020;97(5):842-844.

Realistic in silico generation and augmentation of single-cell RNA-seq data using generative adversarial networks
Marouf M, Machart P, Bansal V, Kilian C, Magruder D, Krebs C, Bonn S
NAT COMMUN. 2020;11(1):166.

Role of regulatory T cells in experimental autoimmune glomerulonephritis
Klinge S, Yan K, Reimers D, Brede K, Schmid J, Paust H, Krebs C, Panzer U, Hopfer H, Mittrücker H
AM J PHYSIOL-RENAL. 2019;316(3):F572-F581.

Single-Cell Transcriptomics Identifies the Adaptation of Scart1+ Vγ6+ T Cells to Skin Residency as Activated Effector Cells
Tan L, Sandrock I, Odak I, Aizenbud Y, Wilharm A, Barros-Martins J, Tabib Y, Borchers A, Amado T, Gangoda L, Herold M, Schmidt-Supprian M, Kisielow J, Silva-Santos B, Koenecke C, Hovav A, Krebs C, Prinz I, Ravens S
CELL REP. 2019;27(12):3657-3671.e4.

Molecular and functional heterogeneity of IL-10-producing CD4+ T cells
Brockmann L, Soukou S, Steglich B, Czarnewski P, Zhao L, Wende S, Bedke T, Ergen C, Manthey C, Agalioti T, Geffken M, Seiz O, Parigi S, Sorini C, Geginat J, Fujio K, Jacobs T, Roesch T, Izbicki J, Lohse A, Flavell R, Krebs C, Gustafsson J, Antonson P, Roncarolo M, Villablanca E, Gagliani N, Huber S
NAT COMMUN. 2018;9(1):5457.

Plasticity and heterogeneity of Th17 in immune-mediated kidney diseases
Krebs C, Panzer U
J AUTOIMMUN. 2018;87:61-68.

IL-17C/IL-17 Receptor E Signaling in CD4 T Cells Promotes T17 Cell-Driven Glomerular Inflammation
Krohn S, Nies J, Kapffer S, Schmidt T, Riedel J, Kaffke A, Peters A, Steinmetz O, Krebs C, Turner J, Brix S, Paust H, Stahl R, Panzer U
J AM SOC NEPHROL. 2018;29(4):1210-1222.

Colitis Promotes a Pathological Condition of the Liver in the Absence of Foxp3 Regulatory T Cells
Mathies F, Steffens N, Kleinschmidt D, Stuhlmann F, Huber F, Roy U, Meyer T, Luetgehetmann M, von Petersdorff M, Seiz O, Herkel J, Schramm C, Flavell R, Gagliani N, Krebs C, Panzer U, Abdullah Z, Strowig T, Bedke T, Huber S
J IMMUNOL. 2018;201(12):3558-3568.

IL-10 Receptor Signaling Is Essential for TR1 Cell Function In Vivo
Brockmann L, Gagliani N, Steglich B, Giannou A, Kempski J, Pelczar P, Geffken M, Mfarrej B, Huber F, Herkel J, Wan Y, Esplugues E, Battaglia M, Krebs C, Flavell R, Huber S
J IMMUNOL. 2017;198(3):1130-1141.

T helper type 17 cells in immune-mediated glomerular disease
Krebs C, Schmidt T, Riedel J, Panzer U
NAT REV NEPHROL. 2017;13(10):647-659.

ISN Nexus 2016 Symposia: Translational Immunology in Kidney Disease—The Berlin Roadmap
Anders H, Rovin B, Jayne D, Brunetta P, Coppo R, Davidson A, Devarapu S, de Zeeuw D, Duffield J, Eulberg D, Fierro A, Floege J, Frese S, Guillevin L, Holdsworth S, Hughes J, Kettritz R, Kluger M, Krebs C, Lapteva L, Levin A, Li J, Lightstone L, Mack M, Mansouri L, McAdoo S, McKinney E, Panzer U, Parikh S, Pusey C, Putterman C, Rabelink T, Radbruch A, Rees A, Reilly M, Reinders M, Remuzzi G, Ruggenenti P, Sacks S, Schall T, Meyer-Schwesinger C, Sharma K, Suzuki Y, Tomas N, Zhao M
KIDNEY INT REP. 2016;1(4):327-339.

Autoimmune Renal Disease Is Exacerbated by S1P-Receptor-1-Dependent Intestinal Th17 Cell Migration to the Kidney
Krebs C, Paust H, Krohn S, Koyro T, Brix S, Riedel J, Bartsch P, Wiech T, Meyer-Schwesinger C, Huang J, Fischer N, Busch C, Mittrücker H, Steinhoff U, Stockinger B, Perez L, Wenzel U, Janneck M, Steinmetz O, Gagliani N, Stahl R, Huber S, Turner J, Panzer U
IMMUNITY. 2016;45(5):1078-1092.

CD4⁺ T Cell Fate in Glomerulonephritis: A Tale of Th1, Th17, and Novel Treg Subtypes
Krebs C, Steinmetz O
MEDIAT INFLAMM. 2016;2016:.

Plasticity of Th17 Cells in Autoimmune Kidney Diseases
Krebs C, Turner J, Paust H, Kapffer S, Koyro T, Krohn S, Ufer F, Friese M, Flavell R, Stockinger B, Steinmetz O, Stahl R, Huber S, Panzer U
J IMMUNOL. 2016;197(2):449-57.

CXCR3+ Regulatory T Cells Control TH1 Responses in Crescentic GN
Paust H, Riedel J, Krebs C, Turner J, Brix S, Krohn S, Velden J, Wiech T, Kaffke A, Peters A, Bennstein S, Kapffer S, Meyer-Schwesinger C, Wegscheid C, Tiegs G, Thaiss F, Mittrücker H, Steinmetz O, Stahl R, Panzer U
J AM SOC NEPHROL. 2016;27(7):1933-42.

IL-17F Promotes Tissue Injury in Autoimmune Kidney Diseases
Riedel J, Paust H, Krohn S, Turner J, Kluger M, Steinmetz O, Krebs C, Stahl R, Panzer U
J AM SOC NEPHROL. 2016;27(12):3666-3677.

Immune Mechanisms in Arterial Hypertension
Wenzel U, Turner J, Krebs C, Kurts C, Harrison D, Ehmke H
J AM SOC NEPHROL. 2016;27(3):677-86.

CC Chemokine Ligand 18 in ANCA-Associated Crescentic GN
Brix S, Stege G, Disteldorf E, Hoxha E, Krebs C, Krohn S, Otto B, Klätschke K, Herden E, Heymann F, Lira S, Tacke F, Wolf G, Busch M, Jabs W, Özcan F, Keller F, Beige J, Wagner K, Helmchen U, Noriega M, Wiech T, Panzer U, Stahl R
J AM SOC NEPHROL. 2015;26(9):2105-2117.

CXCL5 drives neutrophil recruitment in TH17-mediated GN
Disteldorf E, Krebs C, Paust H, Turner J, Nouailles G, Tittel A, Meyer-Schwesinger C, Stege G, Brix S, Velden J, Wiech T, Helmchen U, Steinmetz O, Peters A, Bennstein S, Kaffke A, Llanto C, Lira S, Mittrücker H, Stahl R, Kurts C, Kaufmann S, Panzer U
J AM SOC NEPHROL. 2015;26(1):55-66.

Function of the Th17/interleukin-17A immune response in murine lupus nephritis
Schmidt T, Paust H, Krebs C, Turner J, Kaffke A, Bennstein S, Koyro T, Peters A, Velden J, Hünemörder S, Haag F, Steinmetz O, Mittrücker H, Stahl R, Panzer U
ARTHRITIS RHEUMATOL. 2015;67(2):475-87.

Deficiency of the interleukin 17/23 axis accelerates renal injury in mice with deoxycorticosterone acetate+angiotensin ii-induced hypertension
Krebs C, Lange S, Niemann G, Rosendahl A, Lehners A, Meyer-Schwesinger C, Stahl R, Benndorf R, Velden J, Paust H, Panzer U, Ehmke H, Wenzel U
HYPERTENSION. 2014;63(3):565-71.

Increased expression of (pro)renin receptor does not cause hypertension or cardiac and renal fibrosis in mice
Rosendahl A, Niemann G, Lange S, Ahadzadeh E, Krebs C, Contrepas A, van Goor H, Wiech T, Bader M, Schwake M, Peters J, Stahl R, Nguyen G, Wenzel U
LAB INVEST. 2014;94(8):863-72.

MicroRNA-155 drives TH17 immune response and tissue injury in experimental crescentic GN
Krebs C, Kapffer S, Paust H, Schmidt T, Bennstein S, Peters A, Stege G, Brix S, Meyer-Schwesinger C, Müller R, Turner J, Steinmetz O, Wolf G, Stahl R, Panzer U
J AM SOC NEPHROL. 2013;24(12):1955-65.

AT1 antagonism and renin inhibition in mice: pivotal role of targeting angiotensin II in chronic kidney disease.
Fraune C, Lange S, Krebs C, Hölzel A, Baucke J, Divac N, Schwedhelm E, Streichert T, Velden J, Garrelds I, Danser A, Frenay A, van Goor H, Jankowski V, Stahl R, Nguyen G, Wenzel U
AM J PHYSIOL-RENAL. 2012;303(7):1037-1048.

CCR5 deficiency does not reduce hypertensive end-organ damage in mice
Krebs C, Fraune C, Schmidt-Haupt R, Turner J, Panzer U, Quang M, Tannapfel A, Velden J, Stahl R, Wenzel U
AM J HYPERTENS. 2012;25(4):479-486.

Glomerulonephritiden – Genetische Aspekte
Krebs C, Panzer U
Dialyse aktuell. 2012;16(9):523-527.

Chemokines play a critical role in the cross-regulation of Th1 and Th17 immune responses in murine crescentic glomerulonephritis.
Paust H, Turner J, Riedel J, Disteldorf E, Peters A, Schmidt T, Krebs C, Velden J, Mittrücker H, Steinmetz O, Stahl R, Panzer U
KIDNEY INT. 2012;82(1):72-83.

Immature renal dendritic cells recruit regulatory CXCR6(+) invariant natural killer T cells to attenuate crescentic GN.
Riedel J, Paust H, Turner J, Tittel A, Krebs C, Disteldorf E, Wegscheid C, Tiegs G, Velden J, Mittrücker H, Garbi N, Stahl R, Steinmetz O, Kurts C, Panzer U
J AM SOC NEPHROL. 2012;23(12):1987-2000.

Dimethylarginine dimethylaminohydrolase1 is an organ-specific mediator of end organ damage in a murine model of hypertension.
Sydow K, Schmitz C, von Leitner E, von Leitner R, Klinke A, Atzler D, Krebs C, Wieboldt H, Ehmke H, Schwedhelm E, Meinertz T, Blankenberg S, Böger R, Magnus T, Baldus S, Wenzel U
PLOS ONE. 2012;7(10):48150.

IL-17A production by renal γδ T cells promotes kidney injury in crescentic GN.
Turner J, Krebs C, Tittel A, Paust H, Meyer-Schwesinger C, Bennstein S, Steinmetz O, Prinz I, Magnus T, Korn T, Stahl R, Kurts C, Panzer U
J AM SOC NEPHROL. 2012;23(9):1486-1495.

Protective role for CCR5 in murine lupus nephritis.
Turner J, Paust H, Mathey S, Bramke P, Krebs C, Steinmetz O, Velden J, Haag F, Stahl R, Panzer U
AM J PHYSIOL-RENAL. 2012;302(11):1503-1515.

Podocytes of AT2 receptor knockout mice are protected from angiotensin II-mediated RAGE induction
Rüster C, Franke S, Wenzel U, Schmidthaupt R, Fraune C, Krebs C, Wolf G
AM J NEPHROL. 2011;34(4):309-317.

Characterisation of a novel glycosylphosphatidylinositol-anchored mono-ADP-ribosyltransferase isoform in ovary cells.
Stilla A, Simone D, Dani N, Krebs C, Arrizza A, Corda D, Haag F, Koch Nolte F, Maria D
EUR J CELL BIOL. 2011;90(8):665-677.

The angiotensin II type 2 receptor in renal disease.
Wenzel U, Krebs C, Benndorf R
J RENIN-ANGIO-ALDO S. 2010;11(1):37-41.

Angiotensin II type 2 receptor deficiency aggravates renal injury and reduces survival in chronic kidney disease in mice.
Benndorf R, Krebs C, Hirsch-Hoffmann B, Schwedhelm E, Cieslar G, Schmidt-Haupt R, Steinmetz O, Meyer-Schwesinger C, Thaiss F, Haddad M, Fehr S, Heilmann A, Helmchen U, Hein L, Ehmke H, Stahl R, Böger R, Wenzel U
KIDNEY INT. 2009;75(10):1039-1049.

NAD+ and ATP released from injured cells induce P2X7-dependent shedding of CD62L and externalization of phosphatidylserine by murine T cells.
Scheuplein F, Schwarz N, Adriouch S, Krebs C, Bannas P, Rissiek B, Seman M, Haag F, Koch Nolte F
J IMMUNOL. 2009;182(5):2898-2908.

Rapid development of severe end-organ damage in C57BL/6 mice by combining DOCA salt and angiotensin II.
Kirchhoff F, Krebs C, Abdulhag U, Meyer-Schwesinger C, Maas R, Helmchen U, Hilgers K, Wolf G, Stahl R, Wenzel U
KIDNEY INT. 2008;73(5):643-650.

Effect of (pro)renin receptor inhibition by a decoy peptide on renal damage in the clipped kidney of Goldblatt rats.
Krebs C, Weber M, Steinmetz O, Meyer-Schwesinger C, Stahl R, Danser A, Garrelds I, van Goor H, Nguyen G, Müller D, Wenzel U
KIDNEY INT. 2008;74(6):823-824.

[Quality of life under antihypertensive therapy: essentially for compliance]
Wenzel U, Krebs C
MMW Fortschr Med. 2008;150(24):30-32.

Antihypertensive therapy upregulates renin and (pro)renin receptor in the clipped kidney of Goldblatt hypertensive rats.
Krebs C, Hamming I, Sadaghiani S, Steinmetz O, Meyer-Schwesinger C, Fehr S, Stahl R, Garrelds I, Danser A, van Goor H, Contrepas A, Nguyen G, Wenzel U
KIDNEY INT. 2007;72(6):725-730.

Antihypertensive therapy induces compartment-specific chemokine expression and a Th1 immune response in the clipped kidney of Goldblatt hypertensive rats.
Steinmetz O, Sadaghiani S, Panzer U, Krebs C, Meyer-Schwesinger C, Streichert T, Fehr S, Hamming I, van Goor H, Stahl R, Wenzel U
AM J PHYSIOL-RENAL. 2007;292(2):876-887.

Management of arterial hypertension in obese patients.
Wenzel U, Krebs C
CURR HYPERTENS REP. 2007;9(6):491-497.

ADP-ribosylation of membrane proteins: unveiling the secrets of a crucial regulatory mechanism in mammalian cells.
Koch-Nolte F, Adriouch S, Bannas P, Krebs C, Scheuplein F, Seman M, Haag F
ANN MED. 2006;38(3):188-199.

CD38 controls ADP-ribosyltransferase-2-catalyzed ADP-ribosylation of T cell surface proteins
Krebs C, Adriouch S, Braasch F, Koestner W, Leiter E, Seman M, Lund F, Oppenheimer N, Haag F, Koch-Nolte F
J IMMUNOL. 2005;174(6):3298-305.

Flow cytometric and immunoblot assays for cell surface ADP-ribosylation using a monoclonal antibody specific for ethenoadenosine
Krebs C, Koestner W, Nissen M, Welge V, Parusel I, Malavasi F, Leiter E, Santella R, Haag F, Koch-Nolte F
ANAL BIOCHEM. 2003;314(1):108-15.

NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor
Seman M, Adriouch S, Scheuplein F, Krebs C, Freese D, Glowacki G, Deterre P, Haag F, Koch-Nolte F
IMMUNITY. 2003;19(4):571-82.

Letzte Aktualisierung aus dem FIS: 20.11.2024 - 23:32 Uhr